How COVID-19 affected fitness, sleep, diet, and blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults will attend two visits at the Neurovascular Physiology Laboratory at Indiana University Bloomington and complete questionnaires about health behaviors, sleep, diet, and mental stress. After the first visit participants will wear devices to track sleep and physical activity for about 14 days, complete diet logs for at least three days, undergo 24-hour ambulatory blood pressure monitoring, and collect a 24-hour urine sample for kidney biomarkers. At the second visit participants return devices and undergo physiological testing including body composition, cardiorespiratory fitness, and measures of blood pressure regulation. Data will be used to relate prior COVID-19 severity or PASC status to objective measurements of activity, sleep, blood pressure control, and stress.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Male and female participants. Are between the ages of 18-75. Have a resting blood pressure no higher than 150/90 (stage 2 hypertension). Have a BMI below 35 kg/m2 (otherwise healthy). Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, and cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular).

Do not have any precluding medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) or giving blood (e.g., blood thinners).

Exclusion Criteria:

Younger than 18 or older than 30. Have a resting blood pressure \> 150/90. Have a BMI \> 35 Kg/m2 or \< 18 Kg/m2. History of metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, and cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular).

Medical issues that prevent safe exercise (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis).

Medical issues that prevent giving blood (e.g., blood thinners). Currently pregnant.

Where it's running

• Indiana University School of Public Health
  Bloomington, Indiana, United States Recruiting

Study contacts

• Principal investigator: Austin T Robinson, PhD — Indiana University
• Study coordinator: Sofia Sanchez
• Email: sofosanc@iu.edu
• Phone: 8126226405

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) in Adults

  This study tests and compares the immune responses and tolerability of the latest COVID-19 vaccines from Novavax and Pfizer/BioNTech in adults at risk for severe COVID-19.

  Recruiting Phase 4 Henry M. Jackson Foundation for the Advancement of Military Medicine · Bethesda, Maryland · NCT07287137

• Reconstructing schoolyards to boost children's physical activity and address climate change

  This study is testing if making schoolyards greener can help kids in Stockholm be more active and improve their health over three years.

  Recruiting Karolinska Institutet · Stockholm · NCT05865782

• Omicron-based COVID-19 vaccine with Matrix-M given as a single dose in older adults and high-risk individuals

  A single-dose Omicron-subvariant vaccine with Matrix-M is tested to see if it is safe and can induce an immune response in adults 65+ and in younger adults with conditions that raise the risk of severe COVID-19, who were previously vaccinated.

  Recruiting at 20 sites Phase 4 Sanofi · Fair Oaks, California and 19 other locations · NCT07861542

• Overnight Temperature Regulation to Test Gut Health, Inflammation, and Circadian Rhythms

  This study tests whether two weeks of using the Eight Sleep Pod at night can improve gut bacteria balance, lower inflammation, and strengthen daily temperature and blood pressure rhythms in postmenopausal women and age-matched men with poor sleep.

  Recruiting Eight Sleep Inc. · Newton Center, Massachusetts · NCT07848594

• Heat therapy during reduced activity to protect heart and muscle health

  A randomized trial tests whether daily Finnish dry sauna help preserves cardiovascular and muscle health when daily activity is reduced for seven days in healthy adults.

  Recruiting Brigham Young University · Provo, Utah · NCT07847424

• Automated Non-Invasive Blood Pressure: Tracking Blood Pressure Changes Using SpO2 Data

  This study tests an algorithm that estimates blood pressure changes using data from an SpO2 sensor in patients in the OR, PACU, or ICU who already have invasive BP measured as part of standard care.

  Recruiting GE Healthcare · Helsinki and 1 other locations · NCT07790458

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.