How COVID-19 affected fitness, sleep, diet, and blood pressure
COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise
This project will see if past COVID-19 or long COVID is linked to changes in fitness, physical activity, blood pressure, sleep, and mental stress in adults aged 18 to 75.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Bloomington, Indiana) |
| Trial ID | NCT07128095 on ClinicalTrials.gov |
What this trial studies
Adults will attend two visits at the Neurovascular Physiology Laboratory at Indiana University Bloomington and complete questionnaires about health behaviors, sleep, diet, and mental stress. After the first visit participants will wear devices to track sleep and physical activity for about 14 days, complete diet logs for at least three days, undergo 24-hour ambulatory blood pressure monitoring, and collect a 24-hour urine sample for kidney biomarkers. At the second visit participants return devices and undergo physiological testing including body composition, cardiorespiratory fitness, and measures of blood pressure regulation. Data will be used to relate prior COVID-19 severity or PASC status to objective measurements of activity, sleep, blood pressure control, and stress.
Who should consider this trial
Good fit: Adults aged 18–75 with BMI under 35 kg/m2, resting blood pressure at or below 150/90 mmHg, no major metabolic, pulmonary, or cardiovascular disease, and who can safely exercise and provide blood/urine samples are ideal candidates.
Not a fit: People under 18 or over 75, with BMI >35 or <18, resting blood pressure >150/90, major metabolic/pulmonary/cardiovascular disease, or medical issues that prevent safe exercise or blood draws are unlikely to be eligible or benefit from this protocol.
Why it matters
Potential benefit: If successful, this work could clarify how prior COVID-19 or long COVID affects fitness, blood pressure, sleep, and stress and help guide follow-up care and lifestyle recommendations.
How similar studies have performed: Other observational studies have reported links between COVID-19 or PASC and reduced activity, sleep problems, and cardiovascular changes, but comprehensive multimodal assessments combining wearables, 24-hour BP, urine biomarkers, and exercise testing are less common.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Male and female participants. Are between the ages of 18-75. Have a resting blood pressure no higher than 150/90 (stage 2 hypertension). Have a BMI below 35 kg/m2 (otherwise healthy). Free from metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, and cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular). Do not have any precluding medical issues that prevent participants from exercising (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis) or giving blood (e.g., blood thinners). Exclusion Criteria: Younger than 18 or older than 30. Have a resting blood pressure \> 150/90. Have a BMI \> 35 Kg/m2 or \< 18 Kg/m2. History of metabolic disease (diabetes or renal disease), pulmonary disorders (e.g., COPD, severe asthma, and cystic fibrosis), and cardiovascular disease (peripheral vascular, cardiac, or cerebrovascular). Medical issues that prevent safe exercise (i.e., cardiovascular issues, or muscle/joint issues including painful arthritis). Medical issues that prevent giving blood (e.g., blood thinners). Currently pregnant.
Where this trial is running
Bloomington, Indiana
- Indiana University School of Public Health — Bloomington, Indiana, United States (Recruiting)
Study contacts
- Principal investigator: Austin T Robinson, PhD — Indiana University
- Study coordinator: Sofia Sanchez
- Email: sofosanc@iu.edu
- Phone: 8126226405
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.