A multidimensional sleep health program to improve blood pressure and cardiometabolic risk
Addressing Sleep Duration, Regularity, and Efficiency: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health (The DREAM Study)
This program tests whether a multi-part sleep health intervention can lower blood pressure and improve blood sugar, body measures, and lifestyle in adults aged 30–65 with elevated systolic blood pressure and poor sleep.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 30 Years to 65 Years |
| Sex | All |
| Sponsor | Columbia University Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT06285968 on ClinicalTrials.gov |
What this trial studies
Adults with systolic blood pressure ≥120 mmHg and sub‑optimal sleep are randomized to a control arm that receives standard Life's Essential 8 cardiovascular health materials or to an intervention arm that adds a multidimensional sleep health program. The intervention combines evidence-based sleep hygiene education, personalized sleep feedback, goal setting and a sleep plan, coaching, self-monitoring, and strategies to reduce light and noise in the sleep environment. Outcomes include blood pressure, glycemic control markers, anthropometric adiposity measures, and lifestyle behaviors, and mixed methods are used to study implementation processes and determinants. The approach is pragmatic and designed to be scalable if effective.
Who should consider this trial
Good fit: Adults aged 30–65 who speak English or Spanish, have systolic blood pressure ≥120 mmHg, report sub‑optimal sleep, and have no history of cardiovascular disease or cancer are ideal candidates.
Not a fit: People with already optimal sleep health, a history of cardiovascular disease or cancer, severe psychiatric disorders, cognitive impairment, or who cannot consent are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the intervention could lower blood pressure and improve blood sugar, weight-related measures, and other cardiometabolic risk factors through scalable sleep-focused behavior changes.
How similar studies have performed: Prior research shows sleep affects cardiometabolic health and some behavioral sleep interventions improved sleep and metabolic markers, but multidimensional sleep programs specifically targeting blood pressure are relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 30-65 years * English or Spanish speaking * Systolic blood pressure greater than or equal to 120 mmHg * Sub-optimal sleep health * No history of overt cardiovascular disease * No history of cancer Exclusion Criteria: * Optimal sleep health * History of cardiovascular disease or cancer * Non-English or non-Spanish speaking * Not cognitively able to complete study requirements * Severe psychiatric disorders * Inability to provide informed consent
Where this trial is running
New York, New York
- Columbia University Irving Medical Center, Mailman School of Public Health — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Nour Makarem, PhD — Columbia University
- Study coordinator: Research Project Coordinator
- Email: dream@cumc.columbia.edu
- Phone: 212-305-3317
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.