A multidimensional sleep health program to improve blood pressure and cardiometabolic risk
Official title: Addressing Sleep Duration, Regularity, and Efficiency: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health (The DREAM Study)
Run by Columbia University · NCT06285968 · Data updated 2026-11-12
This program tests whether a multi-part sleep health intervention can lower blood pressure and improve blood sugar, body measures, and lifestyle in adults aged 30–65 with elevated systolic blood pressure and poor sleep.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Columbia University Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | March 12, 2024 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | May 29, 2026 |
| Trial ID | NCT06285968 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 30–65 who speak English or Spanish, have systolic blood pressure ≥120 mmHg, report sub‑optimal sleep, and have no history of cardiovascular disease or cancer are ideal candidates.
✕Probably not a fit
People with already optimal sleep health, a history of cardiovascular disease or cancer, severe psychiatric disorders, cognitive impairment, or who cannot consent are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with systolic blood pressure ≥120 mmHg and sub‑optimal sleep are randomized to a control arm that receives standard Life's Essential 8 cardiovascular health materials or to an intervention arm that adds a multidimensional sleep health program. The intervention combines evidence-based sleep hygiene education, personalized sleep feedback, goal setting and a sleep plan, coaching, self-monitoring, and strategies to reduce light and noise in the sleep environment. Outcomes include blood pressure, glycemic control markers, anthropometric adiposity measures, and lifestyle behaviors, and mixed methods are used to study implementation processes and determinants. The approach is pragmatic and designed to be scalable if effective.
Why it matters
Potential benefit: If successful, the intervention could lower blood pressure and improve blood sugar, weight-related measures, and other cardiometabolic risk factors through scalable sleep-focused behavior changes.
How similar studies have gone: Prior research shows sleep affects cardiometabolic health and some behavioral sleep interventions improved sleep and metabolic markers, but multidimensional sleep programs specifically targeting blood pressure are relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 30+ years * English or Spanish speaking * Systolic blood pressure greater than or equal to 120 mmHg * Sub-optimal sleep health * No history of overt cardiovascular disease * No history of cancer Exclusion Criteria: * Optimal sleep health * History of cardiovascular disease or cancer * Non-English or non-Spanish speaking * Not cognitively able to complete study requirements * Severe psychiatric disorders * Inability to provide informed consent
Where it's running
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Columbia University Irving Medical Center, Mailman School of Public Health
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Nour Makarem, PhD — Columbia University
- Study coordinator: Research Project Coordinator
- Email: dream@cumc.columbia.edu
- Phone: 212-305-3317
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.