Examining blood pressure treatment in ICU patients with brain hemorrhage
Official title: Blood Pressure Treatment in ICU Patients with Subarachniodal Haemorrhage. -Can Blood Pressure Be Used As a Surrogate Marker for Blood Flow
Run by Umeå University · NCT06033378 · Data updated 2026-11-12
This study tests how changing blood pressure affects blood flow in the brains of ICU patients who have had a brain hemorrhage.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Umeå University Academic / other |
| Locations | 1 site (Umeå) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | September 1, 2027 |
| Study ends | September 1, 2028 |
| Registry record updated | March 13, 2025 |
| Trial ID | NCT06033378 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with a coiled or clipped aneurysm and suspected or confirmed vasospasm.
✕Probably not a fit
Patients with a BMI over 30, pregnancy, or severe cardiac or respiratory conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the relationship between blood pressure and cerebral blood flow in patients with subarachnoid hemorrhage (SAH) who may experience vasospasm. Using MRI techniques, the study aims to measure cerebral blood flow at baseline blood pressure and after increasing mean arterial pressure with norepinephrine. The goal is to understand how changes in blood pressure affect cerebral blood flow in this critical patient population. The findings could help optimize blood pressure management in ICU settings for patients with SAH.
Why it matters
Potential benefit: If successful, this study could lead to improved blood pressure management strategies that enhance cerebral blood flow and reduce mortality in patients with subarachnoid hemorrhage.
How similar studies have gone: Other studies have explored blood pressure management in similar contexts, but this specific approach using MRI to correlate blood pressure and cerebral blood flow in SAH patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Coiled or clipped aneurysm * Suspected or confirmed vasospasm Exclusion Criteria: * BMI \>30 * Pregnancy * Pacemaker or other MRI contraindications * Severe congestive heart failure (NYHA III-IV) or cardiac arrhythmia. * Severe respiratory failure or FiO2 \>0.6 * Severe kidney failure
Where it's running
-
Umeå University Hospital
Umeå, Sweden Recruiting
Study contacts
- Principal investigator: Laleh Zarrinkoob — Region Västerbotten
- Study coordinator: Laleh Zarrinkoob, MD, PhD
- Email: laleh.zarrinkoob@umu.se
- Phone: +46707567067
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.