Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Examining blood pressure treatment in ICU patients with brain hemorrhage

Official title: Blood Pressure Treatment in ICU Patients with Subarachniodal Haemorrhage. -Can Blood Pressure Be Used As a Surrogate Marker for Blood Flow

Run by Umeå University · NCT06033378 · Data updated 2026-11-12

This study tests how changing blood pressure affects blood flow in the brains of ICU patients who have had a brain hemorrhage.

More Blood Pressure trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorUmeå University
Academic / other
Locations1 site (Umeå)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedSeptember 1, 2027
Study endsSeptember 1, 2028
Registry record updatedMarch 13, 2025
Trial IDNCT06033378 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with a coiled or clipped aneurysm and suspected or confirmed vasospasm.

Probably not a fit

Patients with a BMI over 30, pregnancy, or severe cardiac or respiratory conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between blood pressure and cerebral blood flow in patients with subarachnoid hemorrhage (SAH) who may experience vasospasm. Using MRI techniques, the study aims to measure cerebral blood flow at baseline blood pressure and after increasing mean arterial pressure with norepinephrine. The goal is to understand how changes in blood pressure affect cerebral blood flow in this critical patient population. The findings could help optimize blood pressure management in ICU settings for patients with SAH.

Why it matters

Potential benefit: If successful, this study could lead to improved blood pressure management strategies that enhance cerebral blood flow and reduce mortality in patients with subarachnoid hemorrhage.

How similar studies have gone: Other studies have explored blood pressure management in similar contexts, but this specific approach using MRI to correlate blood pressure and cerebral blood flow in SAH patients is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Coiled or clipped aneurysm
* Suspected or confirmed vasospasm

Exclusion Criteria:

* BMI \>30
* Pregnancy
* Pacemaker or other MRI contraindications
* Severe congestive heart failure (NYHA III-IV) or cardiac arrhythmia.
* Severe respiratory failure or FiO2 \>0.6
* Severe kidney failure

Where it's running

  • Umeå University Hospital
    Umeå, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.