NIH-funded research R03 grant

PFAS in drinking water and blood pressure in adults and kids

Official title: Assessing effects of PFAS exposure from drinking water on hypertension and blood pressure among adults and children using measured and historically reconstructed PFAS blood levels

Funded at Silent Spring Institute · NIH-11453182 · Data updated 2026-11-12

This project looks at how chemical PFAS in drinking water may be linked to high blood pressure in both adults and children.

More Hypertension research and trials

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionSilent Spring Institute
NIH-funded
Lab location1 site (Newton, United States)
Project startAugust 28, 2026
Project endAugust 27, 2028
Funding year2026
Award (this year)$154,700
NIH project number1R03ES038312-01A1
Project IDNIH-11453182 on NIH RePORTER

Who could benefit from this research

Could help

Adults and children aged 4 and older who have experienced PFAS exposure in communities with drinking water contamination and have blood pressure data.

Less likely to help

Individuals without PFAS exposure or without available blood pressure data may not directly benefit from this study.

What this research studies

Researchers will analyze measured and historical PFAS blood levels to see how exposure relates to blood pressure and hypertension in a diverse group of people, from children as young as 4 to adults over 21. The study builds on existing data from thousands of participants across eight states to examine PFAS mixtures and exposure over time. By using already collected data, the project aims to clarify potential connections between PFAS exposure and cardiovascular risk from childhood into adulthood.

Why it matters

Potential benefit: If successful, findings could inform safer drinking water standards and public health guidance to reduce PFAS-related blood pressure risks.

How similar studies have gone: Prior research suggests PFAS may be linked to hypertension, but this study will address gaps with measured and historical exposure data.

Where this research is happening

  • Silent Spring Institute
    Newton, United States
    Active

Researchers

  • Principal investigator: Schaider, Laurel — Silent Spring Institute
  • Study coordinator: Schaider, Laurel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.