Investigating the link between blood pressure levels and hospital complications

Association of Inpatient Blood Pressure Levels With In-hospital Adverse Events(APPLE Study)

Observational Guangdong Provincial People's Hospital · NCT04226612

This study looks at how blood pressure levels in hospitalized patients might be linked to complications and deaths while they are in the hospital.

Quick facts

Study typeObservational
Enrollment100000 (estimated)
SexAll
SponsorGuangdong Provincial People's Hospital Academic / other
Locations1 site (Guangzhou, Guangdong)
Trial IDNCT04226612 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore how inpatient blood pressure levels correlate with adverse events occurring during hospitalization. It includes a diverse population of hospitalized patients of all ages and races, focusing on the primary outcome of all-cause mortality within the hospital setting. By analyzing blood pressure data collected from these patients, the study seeks to identify potential risks associated with varying blood pressure levels during inpatient care.

Who should consider this trial

Good fit: Ideal candidates for this study are hospitalized patients of any age or race who have recorded blood pressure data.

Not a fit: Patients who are not hospitalized or have missing blood pressure data will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help improve patient monitoring and management strategies in hospitals, potentially reducing adverse outcomes.

How similar studies have performed: While there have been studies examining blood pressure and hospital outcomes, this specific observational approach focusing on all-cause mortality is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inpatient with all age or race;
* Have blood pressure data.

Exclusion Criteria:

* Non-patients;
* Death outside the hospital;
* Missing blood pressure data.

Where this trial is running

Guangzhou, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Blood PressureInpatientAdverse EventsAll-cause mortality
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.