Mapping blood pressure and brain blood flow during anesthesia
Official title: The Effects of Induced Hypertension on Cerebrovascular Hemodynamics During General Anaesthesia
Run by Umeå University · NCT06855407 · Data updated 2026-11-12
This study tests how blood pressure affects blood flow to the brain during anesthesia to help keep patients safe during surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Umeå University Academic / other |
| Locations | 1 site (Umeå) |
| Status | Recruiting |
| Started | December 6, 2024 |
| Main results expected | December 6, 2026 |
| Study ends | June 1, 2027 |
| Registry record updated | March 13, 2025 |
| Trial ID | NCT06855407 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients classified as ASA 1-3, with a BMI between 18.5 and 29.9, and a Mini-Mental State Examination score greater than 23, who are scheduled for elective surgery.
✕Probably not a fit
Patients with pacemakers or other contraindications for MRI will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates the relationship between blood pressure and cerebral blood flow in patients undergoing general anesthesia. Participants will undergo an MRI scan to assess brain blood flow while awake before their planned surgery. The study aims to identify optimal blood pressure levels that ensure adequate brain oxygenation and perfusion during anesthesia. By understanding this relationship, the research seeks to improve management strategies for maintaining cerebral blood flow during surgical procedures.
Why it matters
Potential benefit: If successful, this study could lead to better management of blood pressure during anesthesia, enhancing patient safety and outcomes during surgery.
How similar studies have gone: While the relationship between blood pressure and cerebral blood flow is complex, this approach is novel and has not been extensively tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA classification 1-3 * BMI 18,5-29.9 * MMSE \> 23 * Elective surgery planned. Exclusion Criteria: \- Pacemaker or other contraindications for MRI.
Where it's running
-
Umeå University Hospital
Umeå, Sweden Recruiting
Study contacts
- Study coordinator: Laleh Zarrinkoob, MD, PhD
- Email: laleh.zarrinkoob@umu.se
- Phone: +46707567067
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.