Clinical trial Recruiting at 1 site Interventional Ages 50 to 80

Mapping blood pressure and brain blood flow during anesthesia

Official title: The Effects of Induced Hypertension on Cerebrovascular Hemodynamics During General Anaesthesia

Run by Umeå University · NCT06855407 · Data updated 2026-11-12

This study tests how blood pressure affects blood flow to the brain during anesthesia to help keep patients safe during surgery.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment30 (estimated)
SponsorUmeå University
Academic / other
Locations1 site (Umeå)
StatusRecruiting
StartedDecember 6, 2024
Main results expectedDecember 6, 2026
Study endsJune 1, 2027
Registry record updatedMarch 13, 2025
Trial IDNCT06855407 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients classified as ASA 1-3, with a BMI between 18.5 and 29.9, and a Mini-Mental State Examination score greater than 23, who are scheduled for elective surgery.

Probably not a fit

Patients with pacemakers or other contraindications for MRI will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates the relationship between blood pressure and cerebral blood flow in patients undergoing general anesthesia. Participants will undergo an MRI scan to assess brain blood flow while awake before their planned surgery. The study aims to identify optimal blood pressure levels that ensure adequate brain oxygenation and perfusion during anesthesia. By understanding this relationship, the research seeks to improve management strategies for maintaining cerebral blood flow during surgical procedures.

Why it matters

Potential benefit: If successful, this study could lead to better management of blood pressure during anesthesia, enhancing patient safety and outcomes during surgery.

How similar studies have gone: While the relationship between blood pressure and cerebral blood flow is complex, this approach is novel and has not been extensively tested in similar studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA classification 1-3
* BMI 18,5-29.9
* MMSE \> 23
* Elective surgery planned.

Exclusion Criteria:

\- Pacemaker or other contraindications for MRI.

Where it's running

  • Umeå University Hospital
    Umeå, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.