Antihypertensive self-titration to improve blood pressure control
Official title: Antihypertensive self-titration to improve US blood pressure control
Funded at Brigham and Women's Hospital · NIH-11402581 · Data updated 2026-11-12
A patient-friendly plan to allow adults with high blood pressure to safely adjust their blood pressure medications at home using a provided algorithm.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 20, 2025 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $263,576 |
| NIH project number | 5R34HL178960-02 |
| Project ID | NIH-11402581 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older with hypertension who are willing to use home blood pressure monitoring and follow a self-titration algorithm.
✕Less likely to help
Patients who cannot or prefer not to perform home monitoring or self-titration may not benefit.
What this research studies
This project explores whether patients can self-manage their blood pressure by regularly checking readings and following a pre-set medication-titration plan with their doctor. It builds on evidence that home monitoring and guided self-adjustment can improve control while reducing clinic visits. The study will test how this approach works in real US primary care settings, considering patient preferences, clinician workflows, and regulatory factors before a larger trial. If successful, it could simplify care and help more patients reach their blood pressure goals.
Why it matters
Potential benefit: If successful, patients may achieve better and more consistent blood pressure control with a simpler, at-home management plan.
How similar studies have gone: Previous self-titration approaches have shown safety and potential effectiveness in selected groups, but requires US-context adaptation and larger trials.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Haff, Nancy — Brigham and Women's Hospital
- Study coordinator: Haff, Nancy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.