Micronutrient Enhancement for Development and Health in Adolescent Girls

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a three-arm, randomized, open-label trial enrolling about 3,000 adolescent girls aged 10–18 in rural Bangladesh to compare UNIMMAP-based MMS, MMS+ (UNIMMAP plus calcium, choline, DHA, and higher vitamin D), and standard weekly iron-folic acid for 12 months. The study will assess neurodevelopment, linear growth (height-for-age z-score), bone health, biochemical nutrient status, and functional outcomes, with in-depth clinical assessments and biospecimen collection for future analyses. Primary outcomes include school achievement and height-for-age, with secondary outcomes covering neurocognitive function, bone health, and nutrient biomarkers. The trial is conducted under an individually randomized, open-label design at multiple sites, led by Johns Hopkins Bloomberg School of Public Health, with collaboration from ICDDR,B and the Gates Foundation, and plans to inform nutrition policies for adolescents.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Unmarried 10-18 year old females
* living in their parental home in the study area

Exclusion Criteria:

* Married females under 18 years old;
* those with a history or diagnosis of chronic or congenital heart disease, chronic kidney or lung disease, cancer, and epilepsy

Where it's running

• JiVitA Project Head Quarters
  Rangpur City, Bangladesh Recruiting

Study contacts

• Principal investigator: Parul Christian, DrPH — Johns Hopkins University
• Study coordinator: Parul Christian, DrPH
• Email: pchrist1@jhu.edu
• Phone: 14109552061

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.