Potato-rich diet for cardiometabolic health in adults with type 2 diabetes risk

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants aged 50–70 with stable weight and sedentary to recreational activity will follow either a potato-rich healthy dietary pattern or a typical Western-style diet for 14 weeks, while consuming foods provided to them. The trial aims to see if the potato-based pattern improves factors related to type 2 diabetes risk and cardiovascular health compared with a standard Western diet. Eligible individuals must have no diabetes and meet several health and lifestyle criteria, including a measurable risk score and willingness to adhere to the food plan. The study is conducted at Virginia Tech, led by VT Institute researchers, with no listed collaborators outside the institution. No results are available yet, and the trial design emphasizes dietary modification as the primary intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 50-70 years
* Weight stable for previous 3 months (±5% body weight)
* Sedentary to recreationally active
* ADA-Risk Screener questionnaire score of at least 5
* No plans to gain or lose weight or change physical activity level
* Willing to pick up food daily and consume foods provided for a 14-week period
* Verbal and written informed consent
* Estrogen or testosterone use, lipid-lowering or blood pressure medication and thyroid replacement medication is acceptable, if on stable dose for \>6 months

Exclusion Criteria:

* Body mass index \>40 m2/kg
* Diabetes or diabetes medication
* Weight loss medication or medication influencing glucose metabolism
* Antibiotic, prebiotic or probiotic use in prior 3 months
* TCHOL \>6.2 mmol/L; TG \>4.5 mmol/L
* Blood pressure (BP) \> 159/99 mmHg
* Diagnosed inflammatory bowel disease
* Past or current heart diseases, stroke, respiratory disease, endocrine or metabolic disease, or hematological-oncological disease
* Vegetarian or vegan
* Pregnant or plans to become pregnant
* Food allergies or aversions to diet foods provided
* Estrogen or testosterone usage, lipid-lowering medication, blood pressure medication usage \<6 months

Where it's running

• Virginia Polytechnic Institute and State University
  Blacksburg, Virginia, United States Recruiting

Study contacts

• Principal investigator: Dennis Cladis, PhD — Virginia Polytechnic Institute and State University
• Study coordinator: Dennis Cladis, PhD
• Email: dcladis@vt.edu
• Phone: 540-231-5208

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.