Assessing personalized blood pressure targets using advanced monitoring
Official title: Assessing for Personalized Blood Pressure Targets During Cardiopulmonary Bypass With the Proprietary Cerebral Adaptive Index: A Pilot Investigation
Run by Becton, Dickinson and Company · NCT06492746 · Data updated 2026-11-12
This study is testing a new way to set personalized blood pressure goals for high-risk patients during heart surgery to see if it can improve their recovery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years and up |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Becton, Dickinson and Company Industry-sponsored |
| Locations | 1 site (Evanston, Illinois) |
| Status | Recruiting |
| Started | June 3, 2024 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT06492746 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 45 and older who are scheduled for cardiac surgery and have a high risk for cerebral vascular disease.
✕Probably not a fit
Patients who are non-English speaking, pregnant, or undergoing surgery for congenital heart defects may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study aims to evaluate the Cerebral Adaptive Index for determining personalized blood pressure targets in patients undergoing cardiac surgery with cardiopulmonary bypass. It involves the use of the HemoSphere Advanced Monitoring Platform equipped with Acumen IQ sensors and Tissue Oximetry Monitoring to gather data. The study is observational and focuses on high-risk patients to improve blood pressure management during surgery. By analyzing individual responses, the study seeks to tailor blood pressure targets to enhance patient outcomes.
Why it matters
Potential benefit: If successful, this approach could lead to more effective blood pressure management during cardiac surgeries, potentially reducing complications.
How similar studies have gone: While this approach is innovative, similar studies focusing on personalized monitoring in surgical settings have shown promise, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Signed informed consent 2. Age ≥ 45 years 3. Planned cardiac surgery with Cardiopulmonary Bypass (CPB) 4. Planned monitoring with ForeSight sensor and HemoSphere monitor 5. Planned arterial catheterization for blood pressure monitoring 6. High risk for cerebral vascular disease, defined as: a history of hypertension, pulse pressure \> 60 mmHg, diabetes, stroke, transient ischemic attack, carotid bruit, tobacco smoking, or peripheral vascular disease Exclusion Criteria: 1. Non-English speaking 2. Confirmed to be pregnant 3. Surgery for congenital heart defect 4. Non-availability of HemoSphere with laptop CAI interface
Where it's running
-
Northwestern University Hospital
Evanston, Illinois, United States Recruiting
Study contacts
- Study coordinator: Cristina Johnson
- Email: cc_clinical_affairs@edwards.com
- Phone: 888-713-1564
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.