Condition

Orthostatic Hypotension clinical trials and research

• 11Clinical trials
• 3NIH research projects
• 6Countries

Newest Orthostatic Hypotension clinical trials

All recruiting trials (11)

• Breathing retraining for pregnant women with POTS

  This trial will test whether diaphragmatic breathing exercises help pregnant women with POTS reduce dizziness, rapid heart rate, and other orthostatic symptoms.

  Recruiting Riphah International University · Sialkot, Punjab Province · NCT07579026

• Fainting Detection and Early Warning Using a Wearable Monitor

  This study tests whether signals from a wearable Holter monitor can reflect the severity of orthostatic intolerance in people with fainting disorders.

  Recruiting Boston Scientific Corporation · Rochester, Minnesota · NCT07502599

• How blood pressure and heart rate respond to standing and exercise in healthy people and those with high blood pressure

  See if blood pressure, heart rate, and arterial stiffness during standing and graded bike exercise differ between healthy young adults and older adults with controlled high blood pressure, including those with orthostatic problems or diabetes.

  Recruiting University Medical Centre Ljubljana · Ljubljana · NCT07482462

• Polish registry of heart nerve–targeting treatments (cardioneuroablation and cardioneuromodulation)

  This registry collects information to see how nerve-targeting heart procedures work for adults with fainting, abnormal heart rhythms, or orthostatic problems.

  Recruiting SABAMED Medical Center Ltd. · Rzeszów · NCT07196397

• Using blood pressure and oxygen measurements to predict fall risk in older adults

  This study is trying to see if measuring blood pressure and oxygen levels can help predict fall risks in older adults who have fallen in the past year.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam · NCT06714565

• Transcutaneous spinal stimulation to improve blood pressure after a recent spinal cord injury

  We will try a noninvasive spinal stimulation to see if it raises and steadies blood pressure in people 7–30 days after a thoracic spinal cord injury who have low blood pressure or dizziness when sitting up.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05731986

• Transcutaneous spinal stimulation to stabilize blood pressure after spinal cord injury

  This will test whether noninvasive transcutaneous spinal cord stimulation can raise and stabilize blood pressure in people with chronic high-level spinal cord injuries who experience orthostatic hypotension.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05725499

• Investigating how carbonated water affects blood pressure when standing

  This study is testing if drinking carbonated water can help healthy people maintain their blood pressure better when standing up.

  Recruiting Simon Fraser University · Burnaby, British Columbia · NCT05621460

• Effects of Blood Pressure on Thinking and Brain Blood Flow in Parkinson's Disease

  This study is testing how low blood pressure affects thinking and blood flow in the brains of people with Parkinson's disease who have trouble standing up.

  Recruiting University of California, San Diego · San Diego, California · NCT05400174

• Non-invasive spinal cord stimulation to restore autonomic function after spinal cord injury

  This trial tests whether transcutaneous spinal cord stimulation can help adults with chronic spinal cord injury improve blood pressure control, bladder, bowel, or sexual problems.

  Recruiting at 2 sites University of British Columbia · Vancouver, British Columbia and 1 other locations · NCT05369520

• Breathing carbon dioxide to help with low blood pressure when standing

  This study tests if breathing in carbon dioxide can help people with Neurogenic Orthostatic Hypotension feel better and manage their blood pressure when standing.

  Recruiting University of Calgary · Calgary, Alberta · NCT05295810

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Nighttime CPAP to lower high blood pressure when lying down and reduce daytime dizziness

  This work uses nighttime CPAP for people with neurogenic orthostatic hypotension and supine hypertension to lower blood pressure while lying down and help reduce nighttime urination and daytime lightheadedness.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11241120

• Using positive airway pressure to manage blood pressure issues in older adults

  This study is looking at how using a CPAP machine, which helps with breathing during sleep, might lower high blood pressure that some older adults experience when lying down, and it hopes to make them feel better when they stand up during the day.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10986079

• A device to help manage low blood pressure when standing in older adults

  This study is testing a special belt that helps older adults with neurogenic orthostatic hypotension, a condition that makes them feel dizzy or faint when they stand up, by giving gentle support to improve their blood flow and keep their blood pressure steady.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10753526

Related topics

Quick answers

How many Orthostatic Hypotension clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), Canada (3 trials), Netherlands (1 trial), Pakistan (1 trial), Slovenia (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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