Non-invasive, continuous blood pressure monitoring for prenatal maternal health
Funded at Pyrames, INC. · NIH-11610448 · Data updated 2026-11-12
A wearable device from PyrAmes uses comfortable, non-invasive sensors and smart software to constantly monitor a pregnant person’s blood pressure and heart health so doctors can protect both mom and baby.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pyrames, INC. NIH-funded |
| Lab location | 1 site (Cupertino, United States) |
| Project start | June 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $246,530 |
| NIH project number | 4R33HL168741-03 |
| Project ID | NIH-11610448 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant people in late gestation at risk for hypertensive disorders who would benefit from continuous BP monitoring.
✕Less likely to help
Patients without pregnancy-related hypertension or late-pregnancy monitoring needs may not directly benefit.
What this research studies
This project aims to give pregnant people at risk for high blood pressure a way to continuously track their blood pressure in real time with a comfortable wearable. It combines capacitive pulse sensing and machine learning to estimate systolic, diastolic, and mean blood pressure, plus heart rate and variability. The goal is to enable timely clinical actions during late pregnancy when risk is highest, without the challenges of traditional cuff-based monitoring. The device is designed to be easy to wear and to provide data similar in quality to arterial line monitoring, but with far less risk. By collecting continuous waveform data, clinicians may better prevent complications such as preeclampsia and adverse outcomes for mother and child.
Why it matters
Potential benefit: If successful, the device could allow earlier detection and management of hypertensive disorders in pregnancy, reducing maternal and neonatal complications.
How similar studies have gone: Previous wearable BP monitoring approaches show promise, but this project advances real-time continuous monitoring with a breakthrough device and arterial waveform analysis.
Where this research is happening
-
Pyrames, INC.
Cupertino, United States Active
Researchers
- Principal investigator: Quan, Xina — Pyrames, INC.
- Study coordinator: Quan, Xina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.