NeoMayor: a smartphone-guided lifestyle program to improve heart health in older adults in Chile

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter randomized trial tests NeoMayor, a mobile health intervention, in adults aged 55–75 at elevated cardiovascular risk in Chile. Participants are randomized 2:1 to the NeoMayor program or standard health information for four months, with primary outcome being the Life’s Essential 8 Cardiovascular Health Index. The study also explores how to sustain engagement and implementation in real-world settings. A hybrid Type 1 design combines a confirmatory effectiveness assessment with exploratory implementation analyses. Wearable device support and human health coach elements are included alongside the app to support lifestyle changes.

Why it matters

Who can join: the full rules

Inclusion criteria

* Age between 55 and 75 years
* Able to read and understand written instructions
* Ownership of a smartphone and ability to use it independently
* Physically inactive, defined as performing less than 30 minutes of daily physical activity or less than 2,5 h a week.
* Intermediate or high cardiovascular risk, defined as the presence of at least three of the following: Hypertension (history diagnosed by specialist or general practitioner or ≥ 140 mmHg systolic or ≥90 mm Hg diastolic blood pressure at baseline or current antihypertensive treatment);Diabetes Mellitus (history diagnosed by specialist or general practitioner or fasting blood glucose ≥126 mg/dL or current pharmacologic treatment);Obesity (BMI ≥30 kg/m²); Dyslipidaemia (history diagnosed by specialist or general practitioner or lipid-lowering drugs or baseline total cholesterol ≥ 200 mg/dL or LDL cholesterol ≥100 mg/dL).

Exclusion Criteria

* Dementia defined as a score in the MEFO \< 9
* Significant limitations for independent mobility, including use of assistive devices, frailty, gait instability, or lower-limb painful conditions limiting physical activity
* Uncorrected hearing or visual impairment preventing adequate use of a smartphone
* Chronic neurological, psychiatric, or psychological disorders without regular treatment or follow-up.
* Present severe alcohol or illicit drug use.
* Severe or terminal illness

Where it's running

• Hospital clinico Universidad de Chile. Carlos Lorca Tobar 999
  Santiago, Independencia, Chile Recruiting
• Hospital de Til til Daniel Moya #100
  Tiltil, Chile Recruiting

Study contacts

• Study coordinator: General coordinator
• Email: coordinacionmayores@gmail.com
• Phone: +56977492730

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.