Exploring the link between blood pressure and cognitive decline after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between blood pressure levels and cognitive impairment in patients who have experienced a stroke. It includes patients who have been monitored for over three months post-stroke, collecting data on various factors that may influence cognitive outcomes. The study employs univariate and multivariate regression analyses to assess how blood pressure correlates with the risk of cognitive decline, with subgroup analyses to evaluate effects across different patient demographics.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Patient diagnosed with stroke by CT or MRI,
2. Patients completed the MMSE scale at least once during hospitalization
3. The follow-up time was more than three months after the stroke occurred;

Exclusion criteria:

1. Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months,
2. Patients with pre-existing cognitive impairment before stroke according to their medical records,
3. patients failed to complete MMSE assessment because of aphasia or any other reasons,
4. Patients combined with malignant tumors, patients combined with psychiatric disorders.

Where it's running

• First Affiliated Hospital of Chongqing Medical University
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: Dingqun Bai
• Email: baidingqun@hospital.cqmu.edu.cn
• Phone: 13808380876

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Deep phenotyping to explore recovery in young adults after stroke

  This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.

  Recruiting The Florey Institute of Neuroscience and Mental Health · Heidelberg, Victoria and 1 other locations · NCT07019493

• Stem cell therapy for chronic stroke recovery

  This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.

  Recruiting Phase 2 Hokkaido University Hospital · Sapporo, Hokkaido · NCT06752720

• Investigating brain activation in stroke patients using virtual reality tasks

  This study is testing how virtual reality tasks can help us understand brain activity in stroke patients compared to healthy people, to see if it can aid in their cognitive recovery.

  Recruiting First Affiliated Hospital of Chongqing Medical University · Chongqing, Chongqing Municipality · NCT06703320

• Identifying biomarkers for cognitive impairment after stroke using fNIRS

  This study is trying to find brain signals that can help us understand cognitive problems after a stroke by comparing stroke patients with healthy people while they do thinking tasks.

  Recruiting First Affiliated Hospital of Chongqing Medical University · Chongqing, Chongqing Municipality · NCT06703307

• Using a polypill and lifestyle changes to prevent stroke and cognitive decline

  This study is testing whether a combination of a polypill and lifestyle changes can help people aged 50-75 in Brazil lower their risk of stroke and memory problems.

  Recruiting at 2 sites Phase 3 Hospital Moinhos de Vento · Porto Alegre, Rio Grande do Sul and 1 other locations · NCT05155137

• Reducing blood pressure to prevent cognitive decline in older adults

  This study is testing if better blood pressure management can help older adults with high blood pressure avoid memory problems and dementia.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT05106036

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.