Condition

Hypotension clinical trials and research

• 31Clinical trials
• 7NIH research projects
• 1New in 30 days
• 16Countries

Newest Hypotension clinical trials

All recruiting trials (31)

• Cardiac Arrest: Using Ultrasound to Find Hidden Blood Flow

  This study tests whether patients who have out-of-hospital cardiac arrest but no pulse still show some blood flow on ultrasound and whether that finding relates to survival.

  Recruiting University of Massachusetts, Worcester · Denver, Colorado and 7 other locations · NCT07897370

• Perfusion Index as a Predictor of Spinal Anesthesia–Induced Hypotension in Day-Case Knee Arthroscopy

  This study looks to see if a baseline perfusion index can predict low blood pressure after spinal anesthesia in healthy adults having knee arthroscopy.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle\Ankara · NCT07747441

• Pupil light reflex to predict low blood pressure after spinal anesthesia in cesarean deliveries

  Doctors want to see if a quick eye-pupil test done before spinal anesthesia can predict who might develop low blood pressure after a cesarean delivery.

  Recruiting Al-Azhar University · Damietta · NCT07678723

• Pulse palpation vs arterial blood pressure in circulatory shock

  This study tests how well feeling for a pulse at typical sites matches the actual arterial blood pressure in adults with circulatory shock or risk of failure.

  Recruiting Region Stockholm · Stockholm, Stockholm County · NCT07609095

• Predicting low blood pressure from spinal anesthesia during cesarean section

  This study will test whether body-shape measures (body roundness index and waist circumference) and simple heart/blood pressure indexes can help predict which full-term women having a cesarean with spinal anesthesia will develop low blood pressure.

  Recruiting TC Erciyes University · Kayseri · NCT07499947

• Mindfulness-based breathing before spinal anesthesia for elective cesarean delivery

  This trial will test whether a 5-minute mindfulness slow-breathing exercise just before spinal anesthesia can reduce blood pressure drops and anxiety in pregnant women having elective cesarean delivery.

  Recruiting Ataturk University · Erzurum · NCT07494955

• Skin conductance to predict low blood pressure after spinal anesthesia in older urologic cancer patients

  This project will try to see if skin conductance monitoring can predict which patients aged 65 and older having urologic cancer surgery with spinal anesthesia will develop low blood pressure.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Ankara, Yenimahalle · NCT07481851

• Dexmedetomidine versus dexamethasone added to ropivacaine for supraclavicular nerve block in upper‑limb surgery

  This test compares two medicines added to ropivacaine to see which gives faster onset and longer pain relief for adults having upper‑limb surgery with an ultrasound‑guided supraclavicular nerve block.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sāhīwāl, Punjab Province · NCT07290595

• Noninvasive blood pressure monitoring in newborns using a new device

  This study is testing a new device that uses light to measure blood pressure in newborns to see if it works better than traditional methods.

  Recruiting at 2 sites Massachusetts General Hospital · Boston, Massachusetts and 1 other locations · NCT06994494

• Comparing general anesthesia to combined anesthesia during pancreatic surgery

  This study is testing whether using general anesthesia alone or combined with an epidural is better for people having pancreatic surgery, focusing on how it affects blood pressure and other related issues during and after the operation.

  Recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Mexico City, Mexico City · NCT06953193

• Personalized blood pressure management for high-risk patients undergoing major non-cardiac surgery

  This trial will test whether tailoring blood pressure targets during major non‑cardiac surgery reduces postoperative heart and kidney injury and death in older, high‑risk adults.

  Recruiting at 2 sites Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong and 6 other locations · NCT06952387

• Comparing two types of nerve blocks for pain relief in femur fracture surgery

  This study is testing which of two types of nerve blocks can provide better pain relief for patients having surgery for femur fractures.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sahiwal, Punjab Province · NCT06568770

• Validating the CART BP ring cuffless blood pressure monitor

  This study will test whether the CART BP ring gives blood pressure readings that match the standard cuff method in adults with suspected high or low blood pressure.

  Recruiting Sky Labs · Seoul · NCT06513975

• Effect of phosphocreatine on patients treated by medical emergency teams

  This study tests if giving phosphocreatine to hospitalized patients with serious conditions can help them recover faster and shorten their hospital stays compared to those who receive a placebo.

  Recruiting Phase 3 Università Vita-Salute San Raffaele · Milan · NCT06503016

• Midodrine in heart failure with reduced ejection fraction and low blood pressure

  This study tests whether adding midodrine helps patients with HFrEF and hypotension when standard heart failure therapy is limited by low blood pressure.

  Recruiting Phase 2/3 Ottawa Heart Institute Research Corporation · Ottawa, Ontario · NCT06405555

• Norepinephrine Bolus to Tackle Post-Induction Hypotension in Heart Failure Patients Under General Anesthesia

  A diluted norepinephrine bolus is tested to see if it improves cardiac output in adults with chronic heart failure who develop arterial hypotension after anesthesia is started.

  Recruiting University Hospital, Toulouse · Toulouse · NCT06350929

• Comparing Norepinephrine and Phenylephrine for Blood Pressure Control During Cesarean Delivery

  This study is testing whether using norepinephrine instead of phenylephrine can better control blood pressure during cesarean deliveries with spinal anesthesia.

  Recruiting Phase 4 Hassan II University · Fes and 1 other locations · NCT06248593

• Assessing fluid responsiveness in patients with impaired consciousness

  This study tests different ways to see how well patients with low blood pressure and impaired consciousness respond to fluid treatment in order to improve their care in the ICU.

  Recruiting Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology · Moscow · NCT06180902

• Compare two norepinephrine doses to prevent low blood pressure after spinal anesthesia for C-section

  This study will see if two different infusion rates of norepinephrine can prevent low blood pressure in women having a planned cesarean delivery with spinal anesthesia.

  Recruiting Assiut University · Asyut · NCT06102382

• Comparing noradrenaline and phenylephrine effects on blood flow during brain surgery

  This study is testing whether noradrenaline or phenylephrine is better at keeping blood flow and oxygen levels stable during brain surgery for people with brain tumors.

  Recruiting Phase 2/3 University of Aarhus · Aarhus · NCT06083948

• Evaluating hemodynamic parameters in hypertensive patients during surgery

  This study is testing how well the heart works in people with high blood pressure during major surgeries to see if it can help predict and prevent low blood pressure during anesthesia.

  Recruiting at 4 sites Recep Tayyip Erdogan University · Ankara and 4 other locations · NCT05960604

• Early treatment with noradrenaline for shock in emergency departments

  This study tests if giving noradrenaline right away helps people in shock feel better and recover faster than just using standard fluids.

  Recruiting at 3 sites Phase 3 Odense University Hospital · Copenhagen and 7 other locations · NCT05931601

• Treatment options for low blood pressure in individuals with spinal cord injury

  This study is testing whether different treatments, including a medication called Midodrine, can help people with spinal cord injuries who have low blood pressure feel better and improve their quality of life.

  Recruiting at 2 sites Phase 4 James J. Peters Veterans Affairs Medical Center · West Orange, New Jersey and 1 other locations · NCT05839652

• Optimizing hydrocortisone therapy for newborns undergoing hypothermia treatment after asphyxia

  This study is testing how to best use hydrocortisone treatment for newborns who have had trouble breathing at birth and are being cooled to help their recovery.

  Recruiting Phase 4 Semmelweis University · Budapest, Pest County · NCT05836610

• Hypotension Prediction Index for free-flap reconstruction in head and neck surgery

  This will test whether using the Hypotension Prediction Index reduces episodes of low blood pressure during free-flap reconstruction for people having head and neck cancer surgery.

  Recruiting Poznan University of Medical Sciences · Poznan, Poznań · NCT05738603

• Transcutaneous spinal stimulation to improve blood pressure after a recent spinal cord injury

  We will try a noninvasive spinal stimulation to see if it raises and steadies blood pressure in people 7–30 days after a thoracic spinal cord injury who have low blood pressure or dizziness when sitting up.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05731986

• Transcutaneous spinal stimulation to stabilize blood pressure after spinal cord injury

  This will test whether noninvasive transcutaneous spinal cord stimulation can raise and stabilize blood pressure in people with chronic high-level spinal cord injuries who experience orthostatic hypotension.

  Recruiting Kessler Foundation · West Orange, New Jersey · NCT05725499

• Using Transcutaneous Spinal Cord Stimulation to stabilize blood pressure after spinal cord injury

  This study is testing whether a new method using Transcutaneous Spinal Cord Stimulation can help stabilize blood pressure in people with recent spinal cord injuries during their rehab.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05305118

• Using a glucose measurement system in intensive care for patients with shock

  This study is testing a new glucose monitoring system to see if it can help make checking blood sugar easier and more comfortable for patients in intensive care who are dealing with septic shock.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice · NCT04910841

• Using albumin to improve recovery in critically ill patients with acute kidney injury

  This study is testing whether giving critically ill patients with acute kidney injury a special type of albumin instead of regular saline can help them recover better and need less kidney treatment.

  Recruiting at 9 sites Phase 4 Ottawa Hospital Research Institute · Calgary, Alberta and 15 other locations · NCT04705896

• Effects of different medications on uterine and umbilical vessel function during cesarean deliveries

  This study is testing how different medications used during cesarean deliveries affect blood flow in the uterus and umbilical cord to see which ones are best for keeping mothers and babies healthy.

  Recruiting Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Toronto, Ontario · NCT04053478

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Vascular Triggers of Anesthesia-Related Low Blood Pressure in the Old and Very Young

  This NIH grant explores why people at the youngest and oldest ages are more likely to have dangerously low blood pressure during general anesthesia and how to prevent it.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11360616

• Nighttime CPAP to lower high blood pressure when lying down and reduce daytime dizziness

  This work uses nighttime CPAP for people with neurogenic orthostatic hypotension and supine hypertension to lower blood pressure while lying down and help reduce nighttime urination and daytime lightheadedness.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11241120

• Understanding Blood Pressure Drops During Anesthesia in Very Young and Older Patients

  This work explores why very young children and older adults often experience low blood pressure during surgery and how their blood vessels play a role.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11117114

• Using positive airway pressure to manage blood pressure issues in older adults

  This study is looking at how using a CPAP machine, which helps with breathing during sleep, might lower high blood pressure that some older adults experience when lying down, and it hopes to make them feel better when they stand up during the day.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10986079

• How blood vessel properties affect anesthesia-related low blood pressure in very young and older patients

  This study is looking into why babies and older adults often have low blood pressure when they are put under anesthesia, so we can find better ways to keep them safe during surgery.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10898716

• Wearable device to monitor blood pressure after surgery

  This study is testing a comfortable wearable device that keeps an eye on your blood pressure after surgery, helping to quickly alert caregivers if it drops too low, so you can stay safe and recover better.

  NIH research Vena Vitals, INC. · Irvine, United States · NIH-10760370

• A device to help manage low blood pressure when standing in older adults

  This study is testing a special belt that helps older adults with neurogenic orthostatic hypotension, a condition that makes them feel dizzy or faint when they stand up, by giving gentle support to improve their blood flow and keep their blood pressure steady.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10753526

Related topics

Quick answers

How many Hypotension clinical trials are recruiting right now?

31, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (6 trials), Turkey (Türkiye) (5 trials), Canada (3 trials), Egypt (2 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 2/3: 4, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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