NIH-funded research R01 grant

Cuffless blood pressure monitoring using fast wearable optical sensing

Official title: High speed and wearable speckle contrast optical spectroscopy for cuffless blood pressure measurements

Funded at Boston University (Charles River Campus) · NIH-11403911 · Data updated 2026-11-12

A new wearable device using high-speed optical sensing aims to measure blood pressure without a cuff, making BP tracking easier and more comfortable for adults.

More Blood Pressure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University (Charles River Campus)
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 2, 2025
Project endMay 31, 2029
Funding year2026
Award (this year)$625,312
NIH project number5R01HL177304-02
Project IDNIH-11403911 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older who may benefit from frequent BP monitoring and improved hypertension management.

Less likely to help

Individuals with conditions that preclude wearing a wearable device or who do not require regular BP monitoring may see limited benefit.

What this research studies

This project explores a cuffless, non-invasive method to estimate blood pressure by measuring blood flow in the arm with fast speckle contrast optical spectroscopy. The approach builds on prior work showing accurate BP estimates in healthy individuals during exercise and adds blood flow information to improve accuracy. If successful, it could lead to more comfortable, 24/7 BP monitoring that fits into daily life and improves cardiovascular risk assessment. The research will move from benchtop testing toward wearable implementations in real-world settings.

Why it matters

Potential benefit: If successful, patients could monitor their BP more conveniently and frequently without cuffs, potentially improving hypertension management.

How similar studies have gone: Preliminary results with cuffless BP estimates using SCOS have met accuracy standards in healthy subjects, suggesting potential for broader use.

Where this research is happening

  • Boston University (Charles River Campus)
    Boston, United States
    Active

Researchers

  • Principal investigator: Roblyer, Darren Michael — Boston University (Charles River Campus)
  • Study coordinator: Roblyer, Darren Michael

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.