NIH-funded research R01 grant

ASPIRE: Making self-measured blood pressure work for primary care patients

Official title: ASPIRE: Evaluating Implementation and Effectiveness of Self-Measured Blood Pressure in Primary Care Settings

Funded at Wake Forest University Health Sciences · NIH-11448754 · Data updated 2026-11-12

A practical plan to help adults manage high blood pressure by using home blood pressure readings in regular clinic care.

More Primary Care research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences
NIH-funded
Lab location1 site (Winston-Salem, United States)
Project startSeptember 1, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$665,254
NIH project number1R01HL183999-01A1
Project IDNIH-11448754 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 and older with hypertension or at risk for high blood pressure who receive primary care.

Less likely to help

Patients not using or able to access home blood pressure monitoring devices may see limited benefit.

What this research studies

This project develops and tests a practical toolkit that clinics can use to collect and act on patient self-measured blood pressure readings. It focuses on real-world primary care and uses clinic staff and existing systems to make SMBP data flow into the patient’s health record so providers can adjust treatment promptly. The team designed the toolkit with input from users and follows implementation science to overcome common barriers in under-resourced settings. A small randomized test previously showed higher SMBP engagement and better blood pressure control when the toolkit was used. The current grant aims to expand and sustain this approach across routine care.

Why it matters

Potential benefit: If successful, patients could experience better blood pressure control with fewer clinic visits and more timely treatment adjustments.

How similar studies have gone: Earlier pilot data showed higher SMBP engagement and improved systolic BP with the ASPIRE toolkit.

Where this research is happening

  • Wake Forest University Health Sciences
    Winston-Salem, United States
    Active

Researchers

  • Principal investigator: Alkhatib, Rasha — Wake Forest University Health Sciences
  • Study coordinator: Alkhatib, Rasha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.