Reducing blood pressure in mid-life adults who binge drink

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers compared to alcohol abstainers and moderate drinkers. In the first phase, baseline assessments will be conducted to gather data on these parameters. The second phase involves an 8-week aerobic exercise training program specifically for binge drinkers, with follow-up measurements to evaluate the impact of the intervention on their health metrics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women (50-64 years of age) who do not drink alcohol, who drink at moderate levels, or who binge drink
* Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
* Subjects who can speak and understand English.

Exclusion Criteria:

* a history of diabetes, cardiovascular disease, liver, or renal disease
* current or history of smoking and illicit drug use
* blood pressure ≥160/100 mm Hg
* other known traditional cardiovascular disease risks: obesity (BMI≥35 kg/m2), or hyperlipidemia (total cholesterol\>230 mg/dl and/or LDL cholesterol\>160 mg/dl)
* active infection (in the past 2 months)
* a history of seizures, cancer, or inflammatory disease (i.e., gout or rheumatoid)
* unstable body weight (\>5% change during the past 6 months)
* regular aerobic exercise training (i.e., they engage in 30 min of structured aerobic exercise at least 3 times per week)
* current use of hormone replacement therapy (i.e., estrogen, progesterone, and testosterone)

Where it's running

• University of Texas at Arlington
  Arlington, Texas, United States Recruiting

Study contacts

• Principal investigator: Chueh-Lung Hwang, PhD — University of Texas at Arlington
• Study coordinator: Chueh-Lung Hwang, PhD
• Email: chuehlung.hwang@uta.edu
• Phone: 8172729722

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Reset Challenge: See if 30 days without alcohol reduces high-risk drinking

  This 30-day mobile program tests whether people who drink heavily can cut back or stop drinking for a month, with a focus on those in Oklahoma.

  Recruiting University of Oklahoma · Tulsa, Oklahoma · NCT07591428

• Microbiota Interventions for Accelerated Aging in People with HIV on Alcohol

  This study tests whether two safe dietary supplements—Limosilactobacillus reuteri and blueberry extract—can affect immune aging markers in people with HIV who recently used alcohol.

  Recruiting Phase 1/2 Louisiana State University Health Sciences Center in New Orleans · New Orleans, Louisiana · NCT07462767

• Reducing alcohol and trying a probiotic to improve thinking and brain glucose use in older high-risk drinkers

  This study will test whether reducing alcohol with motivational interviewing plus taking a blinded probiotic or placebo can improve thinking and brain glucose metabolism in people ages 65–84 who drink heavily.

  Recruiting University of Miami · Miami, Florida · NCT07415707

• How alcohol changes the social brain during paired interactions

  This study tests whether drinking alcohol changes brain activity and social bonding during conversations between pairs of regular social drinkers aged 21–30.

  Recruiting University of Illinois at Urbana-Champaign · Champaign, Illinois and 1 other locations · NCT07125534

• Lifestyle for Brain Health — Time-Restricted Eating and Mindfulness

  This 9-month program tests whether combining yoga-based mindfulness with time-restricted eating improves cognition, physical fitness, metabolism, and plasma tau levels in adults 60–80 with subjective or mild cognitive impairment and positive pTau217.

  Recruiting St. Anne's University Hospital Brno, Czech Republic · Brno · NCT07042087

• A large-scale digital health study using Apple devices

  This study is trying to see how data from Apple devices can help us understand and manage different health issues like mental health, sleep, and exercise for a wide range of people.

  Recruiting at 2 sites Apple Inc. · Washington D.C., District of Columbia and 1 other locations · NCT06958523

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.