Condition

Kidney Transplant clinical trials and research

• 64Clinical trials
• 69NIH research projects
• 32Countries

Newest Kidney Transplant clinical trials

All recruiting trials (64)

• Omnisol-preserved kidneys before transplant (hypothermic machine perfusion)

  This study tests whether using Omnisol during hypothermic machine perfusion before kidney transplant can improve early graft function compared with standard preservation.

  Recruiting Vivalyx GmbH · Rotterdam · NCT07792317

• How Propofol and Sevoflurane Affect miRNA in Living Kidney Donors

  This study tests whether using propofol or sevoflurane during donor nephrectomy changes levels of miRNAs in living kidney donors.

  Recruiting University of Gaziantep · Gaziantep, Sahinbey · NCT07760402

• Effects of general vs spinal-epidural anesthesia on kidney transplant biomarkers

  This study tests whether sevoflurane general anesthesia or combined spinal-epidural anesthesia changes markers of cellular stress and protective peptides in adults undergoing kidney transplantation.

  Recruiting University of Gaziantep · Gaziantep, State/Province · NCT07678073

• How kidney transplant patients feel about using artificial intelligence in medicine

  This international survey asks adults who have had a kidney transplant how they feel about AI tools that predict graft loss and what it might mean for their daily care.

  Recruiting at 2 sites Paris Translational Research Center for Organ Transplantation · Paris, Île-de-France Region and 1 other locations · NCT07600541

• Personalized therapeutic stories for children after kidney transplant.

  We will test whether clinician-supervised AI can create age-appropriate, personalized therapeutic stories for children aged 5–12 who have received a kidney transplant and their families.

  Recruiting Paris Translational Research Center for Organ Transplantation · Paris, Île-de-France Region · NCT07532382

• Treating blood vessel problems after a kidney transplant

  This effort will try catheter-based angioplasty and advanced imaging to see if they help kidney transplant recipients with graft dysfunction or stubborn high blood pressure from possible transplant blood‑vessel problems.

  Recruiting at 3 sites University of Aarhus · Aarhus and 2 other locations · NCT07531966

• AIC263029 in kidney transplant recipients with BK virus infection

  This trial tests whether AIC263029 is safe and tolerable and can lower BK virus levels in adults who recently had a kidney transplant and have BK viremia, compared with placebo.

  Recruiting at 14 sites Phase 2 AiCuris Anti-infective Cures AG · Birmingham, Alabama and 13 other locations · NCT07503561

• IDO-1 inhibitor safety in EBV-seronegative kidney transplant recipients getting EBV-positive donor kidneys

  This trial tests whether adding an IDO-1 inhibitor to standard care is safe for adults receiving a kidney from an EBV-infected donor who are EBV seronegative.

  Recruiting Phase 2 University Hospital, Basel, Switzerland · Bern, Canton of Bern and 3 other locations · NCT07368153

• Kidney Protective Jacket to keep donated kidneys cool during transplant

  This project will test a device called the Kidney Protective Jacket to help keep donated kidneys cooler during implantation for adults having their first or second kidney transplant.

  Recruiting iiShield · Westmead, New South Wales · NCT07348458

• Non-contrast MRI tracking of kidney transplant function using donor baselines

  This study will test whether non-contrast MRI scans can track kidney transplant health over time by using donor scans as personalized baselines and by applying the technique to recipients without donor data, for adults who have had or will receive a kidney transplant.

  Recruiting Tongji Hospital · Shiyan, Hubei and 2 other locations · NCT07333495

• Doctor counseling plus smartphone apps to support healthy eating and activity after liver or kidney transplant

  This program tries whether doctor-delivered lifestyle counseling combined with two smartphone apps can help people aged 60 and older who had a liver or kidney transplant eat healthier and be more active.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT07305012

• Long-term health of children born to mothers who had a solid organ transplant

  This project will look for long-term heart, kidney, and immune system problems in people aged 16 and older who were born to mothers who had a kidney, liver, pancreas, heart, or lung transplant.

  Recruiting University Medical Center Groningen · Groningen, Provincie Groningen · NCT07291258

• Letermovir versus valganciclovir to prevent CMV in kidney transplant recipients

  This trial tests whether letermovir works as well as valganciclovir to prevent CMV infection and disease in adults within a week after a kidney transplant.

  Recruiting Phase 4 First Affiliated Hospital Xi'an Jiaotong University · Xi'an, Shaanxi · NCT07266467

• How kidney transplant affects blood flow in the heart's tiny vessels in people with advanced CKD

  This study will try to see if getting a kidney transplant improves blood flow in the small vessels of the heart for people with advanced chronic kidney disease who are on the transplant waitlist.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07222683

• Health and heart risk after a kidney transplant

  This project will follow adults who received a kidney transplant at Royal Derby Hospital to see how cardiovascular risk factors and other health conditions change over the first year.

  Recruiting University Hospitals of Derby and Burton NHS Foundation Trust · Derby, Derbyshire · NCT07205692

• Preventing CMV with CMVIG after conversion to belatacept in kidney transplant recipients

  This will try CMVIG infusions to prevent CMV infection in adult kidney transplant recipients who are CMV‑seronegative and are switching to or already on belatacept.

  Recruiting Phase 1/2 University of Minnesota · Minneapolis, Minnesota · NCT07096453

• Cardiovascular health in children and young adults with chronic conditions

  This project will see if children and young adults (ages 6-25) with chronic health conditions show early signs of aging in large and small blood vessels using noninvasive imaging and clinical tests.

  Recruiting Semmelweis University · Budapest and 2 other locations · NCT07086989

• Predicting diabetes after kidney transplant using microRNA

  We will test whether specific microRNA patterns measured three months after a kidney transplant can predict which adult transplant recipients will develop diabetes in the following one to two years.

  Recruiting at 2 sites University Hospital, Martin · Martin and 1 other locations · NCT07055984

• Short-term effects of once-daily Advagraf plus sirolimus after kidney transplant

  This test tries once-daily extended-release tacrolimus (Advagraf) with sirolimus (Rapamune) in people after kidney transplant to see if it protects the new kidney, improves adherence, and lowers late cytomegalovirus risk.

  Recruiting Shahid Beheshti University of Medical Sciences · Tehran · NCT07033858

• Memory B cells and anti-HLA sensitization in kidney transplant candidates

  This project will test whether analyzing memory B cells in adults with anti-HLA antibodies who are waiting for a kidney transplant can help predict their risk of antibody-related rejection.

  Recruiting University Hospital, Rouen · Rouen · NCT07011238

• Prospective blood collection to detect donor-derived cell-free DNA after kidney transplant

  This project will collect blood from adults who had a kidney transplant to try a blood test that detects donor-derived cell-free DNA to check the transplanted organ.

  Recruiting at 6 sites Devyser Inc. · San Diego, California and 6 other locations · NCT07006831

• CytoGam immunoglobulin to prevent late CMV disease after liver or kidney transplant

  This trial will try giving monthly CytoGam infusions after standard antiviral pills end to see if it lowers the chance of late CMV disease in high-risk liver, kidney, or combined liver-kidney transplant patients (donor positive, recipient negative).

  Recruiting at 2 sites Phase 4 Massachusetts General Hospital · Boston, Massachusetts and 1 other locations · NCT06958796

• Single intragraft injection of C1 esterase inhibitor to improve deceased-donor kidney transplant outcomes

  This trial will test whether injecting Berinert into deceased-donor kidneys before transplant helps adults on dialysis who are receiving high-risk deceased-donor kidney transplants have better kidney function over the first year.

  Recruiting at 4 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Los Angeles, California and 3 other locations · NCT06919003

• Tacrolimus effects on blood sugar after kidney transplant

  This study tests whether how quickly adults break down tacrolimus affects their risk of developing prediabetes or diabetes after a kidney transplant.

  Recruiting at 4 sites Chiesi Poland Sp. z o.o. · Gdansk and 5 other locations · NCT06833463

• Evaluating VX-880 for Type 1 Diabetes in Kidney Transplant Patients

  This study is testing if a new treatment called VX-880 can help people with Type 1 Diabetes who have had a kidney transplant manage their blood sugar better.

  Recruiting at 7 sites Phase 3 Vertex Pharmaceuticals Incorporated · Philadelphia, Pennsylvania and 6 other locations · NCT06832410

• Evaluating Ravulizumab for Reducing Delayed Graft Function After Kidney Transplant

  This study is testing if a new drug called ravulizumab can help kidney transplant patients avoid delayed graft function and reduce the need for dialysis.

  Recruiting at 113 sites Phase 3 Alexion Pharmaceuticals, Inc. · Phoenix, Arizona and 129 other locations · NCT06830798

• Observational study on kidney transplant rejection predictors in Scotland

  This study looks at kidney transplant patients in Scotland to see if certain markers in their urine can help predict if their new kidney might be rejected.

  Recruiting at 2 sites University of Edinburgh · Edinburgh and 1 other locations · NCT06830473

• Immunological reset to help highly sensitized kidney transplant candidates receive transplants

  This study is testing a new treatment to help people who have been waiting a long time for a kidney transplant because of high sensitization levels, to see if it can make it easier for them to get a compatible kidney.

  Recruiting Hospital Universitari Vall d'Hebron Research Institute · Barcelona · NCT06809075

• New method for diagnosing acute rejection in kidney transplants

  This study is testing a new way to diagnose acute rejection in kidney transplants by using a special test on urine to help tailor treatments for better recovery.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06801262

• Preventing CMV after receiving a CMV-positive donor kidney using daily antiviral pills or weekly blood monitoring

  This study will test whether taking daily antiviral pills for 200 days or doing weekly blood checks and treating only if the virus appears is better at preventing CMV disease in adults who get a kidney from a CMV-positive donor and are themselves CMV-negative.

  Recruiting at 6 sites Phase 3 University of California, San Francisco · San Francisco, California and 7 other locations · NCT06798909

• Study on chronic active humoral rejection in kidney transplant patients

  This study looks at how chronic active humoral rejection affects kidney transplant patients' survival and kidney function over time.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06794970

• Investigating how hyperthyroidism affects kidney transplant outcomes

  This study looks at how changes in thyroid function right after a kidney transplant can affect recovery and overall health for patients.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06794203

• Evaluating outcomes of kidney transplant patients with thrombotic microangiopathy

  This study looks at how common a condition called post-transplant thrombotic microangiopathy is in kidney transplant patients and how it affects their recovery and overall health.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, BO · NCT06759961

• Using stem cells to treat chronic kidney disease

  This study is testing whether a single infusion of stem cells can be safely given to people with chronic kidney disease to see how well they tolerate it.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT06752577

• Using MRI to study kidney disease and its complications

  This study is testing if a special type of MRI can help find out more about kidney problems and their effects on heart health in people with acute kidney injury and chronic kidney disease.

  Recruiting University of Edinburgh · Edinburgh · NCT06698614

• Preparing patients for kidney transplantation with endovascular techniques

  This study is testing a new way to prepare the blood vessels of patients with kidney failure so they can safely receive a kidney transplant.

  Recruiting Hospices Civils de Lyon · Bron · NCT06677437

• Lifestyle intervention for weight management in kidney transplant recipients

  This study is testing if a lifestyle program that includes diet and exercise can help kidney transplant recipients avoid gaining weight compared to just getting regular medical care.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT06640179

• Registry for understanding BK virus in kidney transplant patients

  This study is trying to understand how the immune system responds to BK virus infections in kidney transplant patients to see how different treatments can help manage the virus and prevent complications.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06538961

• Non-invasive assessment of kidney transplant condition using advanced imaging techniques

  This study is testing new imaging techniques to see if they can help check the health of kidney transplants in adults without needing to do invasive biopsies.

  Recruiting University of Erlangen-Nürnberg Medical School · Erlangen, Bavaria · NCT06472947

• Home-based training program for kidney transplant recipients

  This study tests whether a home-based training program can help kidney transplant recipients improve their physical strength and function after their surgery.

  Recruiting Oslo University Hospital · Oslo · NCT06379009

• Detecting kidney DNA in transplant patients with potential rejection

  This study is testing a new way to check for kidney transplant rejection by looking at DNA in the blood of patients instead of doing a traditional biopsy.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris and 2 other locations · NCT06351488

• Thiosulfate-enhanced kidney preservation for deceased-donor transplants

  This trial will test whether adding sodium thiosulfate to the solution used to preserve deceased-donor kidneys helps reduce transplant-related injury and improve early kidney function in adults with end-stage renal disease.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06288152

• Assessing heart disease risk in kidney transplant patients using CT scans

  This study is testing if a special type of CT scan can help find out which kidney transplant patients are at higher risk for heart disease before their surgery.

  Recruiting at 5 sites University of Edinburgh · Edinburgh, Lothian and 4 other locations · NCT06234410

• Counseling intervention for kidney transplant candidates

  This study is testing whether group education and counseling for kidney transplant candidates can improve their support and well-being compared to those who only fill out a survey.

  Recruiting Hennepin Healthcare Research Institute · Minneapolis, Minnesota · NCT06147076

• Using dapagliflozin to improve kidney and heart health in kidney transplant recipients

  This study is testing if a diabetes medication called dapagliflozin can help improve kidney and heart health in adults who have had a kidney transplant.

  Recruiting Phase 4 University of Colorado, Denver · Aurora, Colorado · NCT06140537

• Using MR-proADM to predict complications after kidney and liver transplants

  This study is testing if measuring a specific protein can help doctors predict complications like delayed graft function and acute rejection in people who have received kidney or liver transplants.

  Recruiting University of Rome Tor Vergata · Rome · NCT06130046

• Assessing older patients for kidney transplantation

  This study looks at how health and mental well-being assessments can help improve kidney transplant outcomes for older patients.

  Recruiting Institute for Clinical and Experimental Medicine · Prague · NCT06104696

• Comparing empagliflozin and linagliptin for diabetes management in kidney transplant recipients

  This study is testing whether the diabetes medications empagliflozin and linagliptin can help kidney transplant recipients manage their blood sugar and improve their overall health.

  Recruiting Medanta, The Medicity, India · Gurgaon, Haryana · NCT06095492

• Effect of Finerenone on Kidney Transplant Recipients

  This study is testing if a new medication called finerenone can help kidney transplant recipients stay healthy and avoid complications related to their kidneys and heart.

  Recruiting Phase 2 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06059664

• CAR-T cell therapy to help highly sensitized patients receive kidney transplants

  This study is testing if CAR T cell therapy can help highly sensitized patients who have been waiting for a kidney transplant by reducing their antibodies and making it easier for them to receive a transplant.

  Recruiting at 3 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Boston, Massachusetts and 2 other locations · NCT06056102

• Improving kidney transplant outcomes in children

  This study is testing a new combination of medications to see if it can help kids and teens who have had a kidney transplant do better and avoid organ rejection compared to the usual treatment.

  Recruiting at 19 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Birmingham, Alabama and 20 other locations · NCT06055608

• Using Empagliflozin to Improve Outcomes in Kidney Transplant Recipients

  This study is testing if the medication Empagliflozin can help improve kidney function and heart health in veterans who have received kidney transplants.

  Recruiting at 5 sites Phase 4 VA Office of Research and Development · Hines, Illinois and 4 other locations · NCT06013865

• Using biomarkers to guide kidney transplant treatment

  This study is testing if a new way to measure genetic differences can help improve treatment and outcomes for adults getting their first kidney transplant.

  Recruiting at 13 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Birmingham, Alabama and 14 other locations · NCT05917522

• Bone marrow transplant to improve kidney transplant outcomes

  This study is testing if a bone marrow transplant can help kidney transplant patients keep their new kidney healthy without needing as much medication to suppress their immune system.

  Recruiting Phase 1/2 Massachusetts General Hospital · Boston, Massachusetts · NCT05900401

• Warm machine perfusion for older deceased-donor kidneys before transplant

  This study will test whether giving kidneys from deceased donors aged 50 or older six hours of warm machine perfusion before transplant improves kidney function at 12 months for adults getting their first or second kidney transplant.

  Recruiting at 2 sites University Medical Center Groningen · Groningen, Provincie Groningen and 2 other locations · NCT05782543

• Evaluating double voiding to reduce urinary tract infections in kidney transplant recipients

  This study is testing if a technique called double voiding can help kidney transplant recipients reduce their risk of urinary tract infections.

  Recruiting Weill Medical College of Cornell University · New York, New York · NCT05711446

• Using apixaban to prevent strokes in patients with severe kidney disease and atrial fibrillation

  This study is testing if the blood thinner apixaban can help prevent strokes in people with severe kidney disease and atrial fibrillation.

  Recruiting at 29 sites Phase 3 Region Stockholm · Helsinki and 33 other locations · NCT05679024

• A nationwide registry for chronic kidney disease patients

  This study is creating a detailed registry for people with chronic kidney disease, including those on dialysis or who have had a transplant, to help improve their care and support.

  Recruiting Tufts Medical Center · Danville, Pennsylvania · NCT05497518

• Alkali therapy for improving kidney transplant outcomes

  This study is testing if sodium bicarbonate therapy can help improve kidney function and heart health in kidney transplant recipients who have low bicarbonate levels.

  Recruiting Phase 4 University of Colorado, Denver · Aurora, Colorado · NCT05005793

• Exercise program for kidney transplant recipients

  This study is testing whether a structured exercise program can help older patients waiting for a kidney transplant improve their physical function and walking ability compared to those who just receive regular care.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04954690

• Using continuous glucose monitoring in kidney transplant recipients with diabetes

  This study is testing if using a continuous glucose monitor can help kidney transplant recipients with Type 2 diabetes keep their blood sugar levels more stable.

  Recruiting University of California, Davis · Sacramento, California · NCT04783441

• Evaluating bone density and vascular calcifications after kidney transplant

  This study is looking at how bone and blood vessel health change over time in people who have recently had a kidney transplant to help improve their recovery.

  Recruiting University of Liege · Liège · NCT04713774

• Using PET scans to diagnose subclinical rejection in kidney transplant patients

  This study is testing if a special type of scan can safely spot early signs of kidney rejection in transplant patients without needing a painful biopsy.

  Recruiting University of Liege · Liège, Liège · NCT04702022

• Combined kidney and blood stem cell transplant from a sibling donor

  This study is testing a new treatment for kidney transplant recipients to see if using a sibling's blood stem cells can help them accept their new kidney without needing lifelong medications to prevent rejection.

  Recruiting Phase 1/2 University of California, Los Angeles · Los Angeles, California · NCT03707262

NIH-funded research (newest 40 of 69)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Microbial clues to diagnose and predict infections in kidney transplant patients

  A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11471530

• Immunological mechanisms behind treatment-resistant kidney transplant rejection

  This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11449432

• Complement-Bound Exosomes and Kidney Transplant Immunity

  This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11442411

• Blood vessel signals predicting heart problems after kidney transplant

  This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.

  NIH research Yale University · New Haven, United States · NIH-11441506

• Understanding how BK virus links infection to kidney transplant rejection

  This project looks at how BK polyomavirus reactivation affects kidney transplant patients and aims to use pre-transplant T cell information to tailor immunosuppression and monitoring.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11436797

• Characterization of a LILRB3 SNP cluster and its link to kidney transplant outcomes

  A study in kidney transplant recipients looks at genetic factors that may be tied to higher risk of graft failure.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11434426

• Optimizing a prehabilitation program for kidney transplant candidates on dialysis

  A program to improve physical function and readiness for kidney transplant in people on dialysis is being developed and tested to help candidates stay healthier while they wait.

  NIH research New York University School of Medicine · New York, United States · NIH-11421433

• Remote home-based rehab to improve fitness before kidney transplant

  A home-based rehabilitation program is being tested to help adults awaiting kidney transplants become fitter and stronger while they wait.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11419006

• Interventions to Promote Kidney Transplant Empowerment

  A targeted program to help adults with kidney disease navigate and complete the steps toward kidney transplant by addressing barriers and streamlining evaluation and waitlisting.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11415080

• Cardiovascular and Kidney Protection with SGLT2 Inhibitors after Kidney Transplant

  A study testing whether SGLT2 inhibitors can improve long-term heart and kidney health for adults who have had a kidney transplant.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11404810

• Improve how patients and providers talk about live-donor kidney transplants

  A study will look at how conversations during kidney transplant evaluations influence whether people receive a live-donor transplant.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11401474

• Virtually Supervised Exercise for Kidney Transplant Candidates

  A home-based, online-guided exercise program helps people waiting for a kidney transplant stay stronger and fitter.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11401349

• Virtually supervised exercise program for people waiting for a kidney transplant

  This project offers a home-based, virtually supervised exercise program to help people on the kidney transplant waitlist keep and rebuild muscle and stay more mobile.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11400620

• Impact of disability protections on kidney transplant access for people with developmental disabilities

  A nationwide study checks whether anti-discrimination laws help people with intellectual or developmental disabilities get kidney transplants sooner.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11388653

• Phage therapy to prevent recurrent UTIs in kidney transplant patients

  A small clinical trial will test whether targeted viruses (phages) can lower recurrent urinary infections in women with kidney transplants, using phages that attack E. coli and K. pneumoniae.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11387805

• AI-assisted kidney transplant biopsy interpretation to reduce discards

  A kidney transplant study uses artificial intelligence to help interpret biopsy images so more usable kidneys aren’t discarded.

  NIH research New York University School of Medicine · New York, United States · NIH-11380794

• APOL1 Gene Variants in Kidney Donors and Long-Term Transplant Outcomes

  This grant studies how APOL1 gene variants in kidney donors affect long-term results for people who receive kidney transplants.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11373045

• Genetic factors beyond APOL1 and kidney transplant outcomes

  This project tests whether genetic factors besides APOL1 influence how well kidney transplants last, using data from 2,800 donor-recipient pairs.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11372185

• Helping adults get the support they need to complete the kidney transplant process

  This program builds patient- and caregiver-informed supports to help adults with kidney failure complete the steps needed to get a kidney transplant and fair access to waitlisting.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11370842

• AI tools to improve pre-transplant kidney biopsy readings

  This project will use artificial intelligence to help doctors read donor kidney biopsy images so more usable kidneys reach people on the transplant waitlist.

  NIH research New York University School of Medicine · New York, United States · NIH-11369502

• New strategies to boost regulatory T cells and pause immunosuppressants after kidney transplant

  This grant explores using engineered immune cells to help kidney transplant patients keep a healthy graft without lifelong immunosuppressive drugs.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11365827

• Strategies to boost regulatory dendritic cells and reduce drugs in kidney transplant success

  A research project aims to improve kidney transplant survival by using special immune cells and targeted therapies to reduce or stop the need for long-term medications.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11365819

• Molecular HLA matching to help kidneys last longer after transplant

  This project looks at whether matching donor and recipient HLA at the molecular level helps people who receive deceased-donor kidney transplants keep their new kidneys working longer.

  NIH research New York University School of Medicine · New York, United States · NIH-11361992

• KPoP: Preventing CMV in kidney transplant recipients with D+R- risk

  A kidney transplant study tests a preemptive approach to prevent CMV disease in patients who received a donor organ from a CMV-positive donor and are CMV seronegative.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11337540

• Post-Kidney Transplant Dementia and Alzheimer’s Risk: Predicting Who Might Need Help

  A project uses pre-transplant data from older kidney transplant patients to forecast who might develop dementia or Alzheimer’s after transplantation.

  NIH research New York University School of Medicine · New York, United States · NIH-11337057

• Optimizing Immunosuppression and EBV-Seronegative Kidney Allocation to Reduce PTLD Risk

  This grant explores how adjusting immunosuppression and kidney donor matching by EBV status could lower the risk of EBV-related cancers in kidney transplant patients.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11332890

• Better donor organ checks to improve kidney transplant outcomes

  This project looks for cell and gene markers in donor kidneys and in transplant recipients' blood that predict which deceased-donor transplants will work best.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11332443

• Super-resolution ultrasound to image tiny blood vessels in kidney transplants

  A new ultrasound method will be used to see and measure tiny blood vessels in transplanted kidneys to help people with kidney transplants monitor graft health.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11321170

• Apoptotic donor white cells to help kidney transplant tolerance

  A new approach tests giving a few donor immune cells that are dying off, along with short-term immune drugs, to help kidney transplant patients accept a transplant long-term.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11311943

• COVID-19 vaccine responses in kidney transplant patients taking mycophenolate

  This project looks at how the anti-rejection drug mycophenolate affects COVID-19 vaccine protection in people with kidney transplants.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11283983

• Safety and potential heart-healthy benefits of SGLT2 inhibitors for kidney transplant patients with diabetes

  A multi-site study will gently test whether SGLT2 inhibitors can be safely used in kidney transplant recipients who have type 2 diabetes, to see if it helps both the graft and heart health.

  NIH research Omaha VA Medical Center · Omaha, United States · NIH-11252581

• Investigating immune responses in kidney transplant rejection

  This study is looking at how certain immune cells in your body might affect the success of kidney transplants, especially if you've had previous infections, to help find better treatments that could reduce the need for long-term medication after surgery.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11248001

• Dapagliflozin to protect kidney transplant function and heart health

  This research will test whether dapagliflozin helps adults with a kidney transplant—especially those with type 2 diabetes—keep their new kidney working and reduce heart-related problems.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11238529

• Investigating T cells involved in kidney transplant rejection

  This study is looking at how certain immune cells called CD8+ T cells play a role in kidney transplant rejection, especially in patients who have had past infections, to help find better ways to prevent rejection and improve transplant success.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11232890

• AI-assisted review of donated kidney biopsy images

  Using an AI tool to help pathologists read donor kidney biopsies so more usable deceased-donor kidneys can be transplanted for people on the waitlist.

  NIH research New York University School of Medicine · New York, United States · NIH-11181564

• Virus-based treatment to stop repeated urinary infections after a kidney transplant

  This trial gives phage medicines to women with kidney transplants who keep getting urinary tract infections to try to lower future infections by targeting the bacteria in the gut and bladder.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11173628

• At-home guided exercise program for people awaiting a kidney transplant

  A home-based, video-supervised exercise program to help people waiting for a kidney transplant stay stronger and more mobile.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11167635

• How state laws and ableism affect kidney transplant access for people with intellectual or developmental disabilities

  This project looks at whether state anti-discrimination laws and other patient factors help people with intellectual or developmental disabilities get fair access to kidney transplants.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11146386

• Understanding genes beyond APOL1 that affect kidney transplants

  This research looks at additional genetic differences, besides the APOL1 gene, that might affect how well kidney transplants work, especially for people of African ancestry.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11138741

• APOL1 Gene and Long-Term Kidney Transplant Outcomes

  This project looks at how a gene called APOL1 in kidney donors might affect how well transplanted kidneys work over time for patients.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11137838

Related topics

Quick answers

How many Kidney Transplant clinical trials are recruiting right now?

64, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 32 countries. The most sites are in United States (26 trials), Italy (7 trials), France (6 trials), United Kingdom (5 trials), Canada (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 4: 5, Phase 3: 4, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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