Condition

Kidney Failure clinical trials and research

• 17Clinical trials
• 7NIH research projects
• 19Countries

Newest Kidney Failure clinical trials

All recruiting trials (17)

• Omnisol-preserved kidneys before transplant (hypothermic machine perfusion)

  This study tests whether using Omnisol during hypothermic machine perfusion before kidney transplant can improve early graft function compared with standard preservation.

  Recruiting Vivalyx GmbH · Rotterdam · NCT07792317

• Kidney and liver blood flow patterns after major trauma

  We will use bedside ultrasound to see whether abnormal kidney and liver blood flow patterns occur in adults admitted to the ICU after major trauma and whether those patterns link to acute kidney injury or the need for mechanical ventilation.

  Recruiting Azienda Usl di Bologna · Bologna · NCT07492511

• Home-based exercise to boost fitness for people waiting for a kidney transplant

  This study tests whether a 12-week, home-based exercise program plus a wearable activity tracker helps adults on the kidney transplant waiting list increase daily activity and improve physical function.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07446296

• CRISPR-edited donor kidney transplant to reduce rejection risk

  This trial will see if donor kidneys edited with CRISPR to turn off key HLA genes can lower rejection in adults with end-stage kidney disease receiving transplants.

  Recruiting Phase 1/2 American Organ Transplant and Cancer Research Institute LLC · Beijing, Changping · NCT07053462

• Effect of Daratumumab on Kidney Diseases Related to Monoclonal Gammopathy

  This study is testing whether daratumumab can help improve kidney function and overall health in people with kidney diseases linked to monoclonal gammopathy.

  Recruiting Phase 2 Helsinki University Central Hospital · Helsinki · NCT06889948

• Examining amino acid loss in patients undergoing kidney treatment

  This study looks at how much amino acid is lost in patients receiving kidney treatment in the ICU compared to those who aren't, to help improve nutrition for people with kidney problems.

  Recruiting Medical University of Vienna · Vienna, State of Vienna · NCT06659835

• Starting peritoneal dialysis gradually with an incremental prescription

  This trial will test whether beginning adults on peritoneal dialysis with a lower, gradually increased dose (incremental PD) works as well as starting full-dose PD for people who are just starting dialysis.

  Recruiting at 10 sites The University of Queensland · Blacktown, New South Wales and 13 other locations · NCT06642597

• High-protein egg white pudding for people on dialysis

  This trial will try whether giving an egg white protein pudding to adults on in-center hemodialysis with low albumin helps their nutrition compared with a standard supplement (Ensure Plus).

  Recruiting at 2 sites Seven Oaks Hospital Chronic Disease Innovation Centre · Winnipeg, Manitoba and 1 other locations · NCT06343727

• Transplantation of Bladders or Kidneys with Bladders from Deceased Donors

  This study is testing if transplanting bladders from deceased donors can help people with severe bladder diseases, including those who need both a kidney and bladder transplant.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT06337942

• Maribavir for CMV in adults with kidney failure after transplantation

  This project will see if maribavir is safe for adults with severe kidney failure (including people on dialysis) who develop CMV after a transplant by reviewing existing medical records.

  Recruiting at 9 sites Takeda · Anderlecht, Brussels Capital and 24 other locations · NCT06243731

• Multifactorial intervention to lower cardiovascular disease risk in type 1 diabetes

  This study is testing whether a combination of treatments can help people with type 1 diabetes who are at high risk for heart problems stay healthier and avoid serious issues like heart attacks and kidney failure.

  Recruiting at 2 sites Phase 3 Steno Diabetes Center Copenhagen · Copenhagen and 1 other locations · NCT06082063

• CAR-T cell therapy to help highly sensitized patients receive kidney transplants

  This study is testing if CAR T cell therapy can help highly sensitized patients who have been waiting for a kidney transplant by reducing their antibodies and making it easier for them to receive a transplant.

  Recruiting at 3 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Boston, Massachusetts and 2 other locations · NCT06056102

• Bone marrow transplant to improve kidney transplant outcomes

  This study is testing if a bone marrow transplant can help kidney transplant patients keep their new kidney healthy without needing as much medication to suppress their immune system.

  Recruiting Phase 1/2 Massachusetts General Hospital · Boston, Massachusetts · NCT05900401

• Incremental dialysis to improve health outcomes for kidney failure patients

  This study is testing if a new way of doing dialysis called incremental dialysis can help kidney failure patients feel better and improve their quality of life compared to the usual method.

  Recruiting at 13 sites The University of Queensland · Concord, New South Wales and 17 other locations · NCT04932148

• Evaluating the Shingrix vaccine in kidney transplant recipients

  This study tests how well the Shingrix vaccine works and its safety for people waiting for a kidney transplant.

  Recruiting at 4 sites Phase 3 University of Colorado, Denver · Aurora, Colorado and 3 other locations · NCT04128189

• Comparison of Custodiol-N and Custodiol solutions for organ preservation in transplantation

  This study is testing if a new organ preservation solution called Custodiol-N works just as well as the standard Custodiol solution for keeping kidneys, livers, and pancreas healthy for transplant.

  Recruiting at 4 sites Phase 3 Dr. F. Köhler Chemie GmbH · Graz and 3 other locations · NCT03627013

• Biobank for kidney transplant donors and recipients

  This study is setting up a collection of samples from kidney transplant donors and recipients to help researchers find ways to improve kidney transplant outcomes in the future.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, BE · NCT01331668

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving Access to Kidney Care for People at Highest Risk of Kidney Failure

  A patient-facing program to help people at high risk of kidney failure get timely nephrology care and options for kidney replacement.

  NIH research Emory University · Atlanta, United States · NIH-11602189

• Improving Access to Nephrology Care for People at Highest Risk of Kidney Failure

  This grant aims to help adults with advanced kidney disease get timely nephrology care and better options for kidney replacement.

  NIH research Emory University · Atlanta, United States · NIH-11415196

• Easier access to kidney care for people at high risk of kidney failure

  This program will use care teams, clinic changes, and patient support to help adults with advanced chronic kidney disease get timely specialist care, permanent dialysis access, and education before they need dialysis or a transplant.

  NIH research Emory University · Atlanta, United States · NIH-11371329

• Investigating the effects of low-dose vitamin D on kidney failure patients

  This study is looking at how small amounts of vitamin D might help people with kidney failure who are on dialysis, especially in keeping their hearts healthy, and it aims to find the safest and most effective way to use vitamin D for managing bone and mineral issues in these patients.

  NIH research University of Washington · Seattle, United States · NIH-11081703

• Improving decision-making for older adults considering kidney transplants

  This study is all about helping older adults who are thinking about getting a kidney transplant by listening to their experiences and those of their families and doctors, so we can make the process easier and more supportive for everyone involved.

  NIH research University of Washington · Seattle, United States · NIH-11018510

• New treatment for chronic kidney disease using a special peptide

  This study is exploring a new pill that could help people with chronic kidney disease by improving kidney function and reducing damage, and it's designed to find out how safe and effective this treatment can be.

  NIH research Fibrotherapeutics, INC. · Charleston, United States · NIH-11005463

• Impact of Hurricane Maria on kidney care and patient outcomes in Puerto Rico

  This study looks at how Hurricane Maria affected people with kidney failure in Puerto Rico by making it harder for them to get the dialysis they need, and it aims to understand how this has impacted their health and care over time, so we can better prepare for future disasters.

  NIH research Brown University · Providence, United States · NIH-10817224

Related topics

Quick answers

How many Kidney Failure clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (5 trials), Italy (2 trials), Australia (2 trials), Belgium (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 1/2: 2, Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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