Improve how patients and providers talk about live-donor kidney transplants
Official title: Improving Utilization of Live Donor Kidney Transplant through Effective Patient-Provider Communication
Funded at Temple Univ of the Commonwealth · NIH-11401474 · Data updated 2026-11-12
A study will look at how conversations during kidney transplant evaluations influence whether people receive a live-donor transplant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | June 5, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $595,366 |
| NIH project number | 5R01DK134630-04 |
| Project ID | NIH-11401474 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with chronic kidney disease or end-stage kidney disease who are candidates for kidney transplant and are exploring live-donor options.
✕Less likely to help
Patients who are not considering live-donor transplants or are not evaluating transplant options may see little direct benefit.
What this research studies
This project will mix numbers and real-life experiences to understand which communication behaviors during transplant evaluations help patients pursue live-donor kidney transplants. Researchers will collect data from patients and providers, then analyze how words, attitudes, and interactions relate to getting inquiries, evaluations, and actual transplants. The goal is to design an intervention that improves communication so more patients consider and obtain live-donor options. Results could guide training for clinicians and tools to support patient conversations.
Why it matters
Potential benefit: If successful, the project could lead to more patients receiving live-donor transplants by improving communication in evaluations.
How similar studies have gone: Previous work shows communication patterns influence health decisions, but this study tests specific transplant-evaluation conversations.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Siminoff, Laura a. — Temple Univ of the Commonwealth
- Study coordinator: Siminoff, Laura a.
Related research
Other NIH-funded projects on the same topics.
-
Microbial clues to diagnose and predict infections in kidney transplant patients
A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.
-
Immunological mechanisms behind treatment-resistant kidney transplant rejection
This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.
-
Complement-Bound Exosomes and Kidney Transplant Immunity
This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.
-
Blood vessel signals predicting heart problems after kidney transplant
This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.
-
Understanding how BK virus links infection to kidney transplant rejection
This project looks at how BK polyomavirus reactivation affects kidney transplant patients and aims to use pre-transplant T cell information to tailor immunosuppression and monitoring.
-
Characterization of a LILRB3 SNP cluster and its link to kidney transplant outcomes
A study in kidney transplant recipients looks at genetic factors that may be tied to higher risk of graft failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.