Post-Kidney Transplant Dementia and Alzheimer’s Risk: Predicting Who Might Need Help
Official title: Post-Kidney Transplant Dementia and Alzheimer's Disease Prediction Leveraging the Pre-Transplant Evaluation Data
Funded at New York University School of Medicine · NIH-11337057 · Data updated 2026-11-12
A project uses pre-transplant data from older kidney transplant patients to forecast who might develop dementia or Alzheimer’s after transplantation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 2, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $1,423,551 |
| NIH project number | 1R01AG099916-01 |
| Project ID | NIH-11337057 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older adults awaiting or undergoing kidney transplantation who have pre-transplant data available.
✕Less likely to help
Patients whose data do not reveal risk signals or who do not experience post-transplant cognitive changes may see limited direct benefit.
What this research studies
This research looks at people who have had kidney transplants and are aged well into older adulthood. It aims to build models that use information available before transplant to predict future cognitive decline and dementia risk. The study combines traditional factors with new types of data to identify high-risk patients so they can receive early cognitive support and tailored care after transplant. If successful, clinicians could use these predictions to guide monitoring, caregiver training, and treatment plans.
Why it matters
Potential benefit: It could help clinicians identify high-risk patients early and tailor post-transplant care to reduce dementia risk.
How similar studies have gone: Previous models in general older adults have limited accuracy for kidney transplant patients; this study seeks to improve prediction in this specific population.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Mcadams Demarco, Mara a. — New York University School of Medicine
- Study coordinator: Mcadams Demarco, Mara a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.