Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating bone density and vascular calcifications after kidney transplant

Official title: Evolution of Bone Density, Bone Micro-architecture and Vascular Calcifications in Patients After Kidney Transplantation

Run by University of Liege · NCT04713774 · Data updated 2026-11-12

This study is looking at how bone and blood vessel health change over time in people who have recently had a kidney transplant to help improve their recovery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of Liege
Academic / other
Drugs / interventionsdenosumab
Locations1 site (Liège)
StatusRecruiting
StartedSeptember 1, 2020
Main results expectedDecember 12, 2025
Study endsDecember 13, 2026
Registry record updatedDecember 18, 2024
Trial IDNCT04713774 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who have received a kidney transplant within the last three months.

Probably not a fit

Patients who have received bisphosphonate treatment or other bone-active medications in the last three months, as well as those undergoing multiple organ transplants, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study assesses bone architecture and vascular calcifications in recent kidney transplant patients using high-resolution peripheral quantitative CT and DEXA scans. It aims to understand the evolution of bone and vascular health over time by analyzing nephrological clinical parameters and biological markers related to mineral metabolism. The study seeks to establish relationships between bone mass, muscle mass, and the presence of vascular calcifications, which are critical for improving patient outcomes post-transplant.

Why it matters

Potential benefit: If successful, this study could lead to better prevention and management of bone and vascular complications in kidney transplant patients.

How similar studies have gone: While the specific approach of this study may be novel, there is existing literature on the complications of bone and vascular health in kidney transplant patients, indicating a need for further exploration.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old
* Recent kidney transplant patients (\<3 months)
* Medical history available
* Biological parameters of the past year available

Exclusion Criteria:

* Treatment with bisphosphonate, RANKL inhibitor or SERM with bone action in the last 3 months before the transplant
* Multiple organ transplant patients

Where it's running

  • Centre Hospitalier Universitaire de Liège
    Liège, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.