Condition

Frailty Syndrome clinical trials and research

• 19Clinical trials
• 14Countries

Newest Frailty Syndrome clinical trials

All recruiting trials (19)

• Urinary incontinence in older adults: how leakage and bladder residuals relate to frailty

  This study tests whether the severity of urinary leakage and leftover urine after voiding are linked to frailty and other geriatric outcomes in older adults visiting a urology clinic.

  Recruiting Karabuk University · Karabük, Merkez · NCT07813702

• Combined inspiratory muscle training with blood flow restriction for frail older adults

  This study tests whether a short program of breathing muscle training with blood flow restriction is feasible and can improve function in frail older adults.

  Recruiting Taipei Medical University · Taipei · NCT07573995

• Multimodal prehabilitation before elective hip or knee replacement for frail older adults

  This program will test whether a tailored multimodal prehabilitation package can help frail adults aged 70 and older who are waiting at least two months for elective hip or knee replacement do better around the time of surgery.

  Recruiting University of Iceland · Reykjavik · NCT07465159

• Conventional Exercise vs Pilates in Prefrail and Frail Older Adults

  This study tests whether Pilates or conventional exercise helps improve frailty status and physical function in people aged 60 and older who are prefrail or frail.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Istanbul · NCT07458048

• Modified Essential Frailty Toolset for older adults having major elective non-cardiac surgery

  This project will test whether a quick frailty checklist (the modified Essential Frailty Toolset) can predict complications and hospital readmissions in people aged 70 and older scheduled for major elective non-cardiac surgery.

  Recruiting University of Iceland · Reykjavik, Hofudborgarsvaedid · NCT07452263

• Quick frailty tests to predict outcomes after elective surgery

  This project will test whether quick frailty tests (PRISMA-7, timed up and go, and clock drawing) can predict postoperative outcomes for people 70 and older having intermediate or major elective surgery.

  Recruiting University of Iceland · Reykjavik, Hofudborgarsvaedid · NCT07367828

• Digital care-coordination support for family caregivers after an emergency-department discharge

  This pilot tests whether the Monka digital app helps family caregivers of adults discharged from the emergency department reduce caregiver burden and improve post-discharge outcomes.

  Recruiting Fondation Hôpital Saint-Joseph · Paris · NCT07348081

• Volunteer-led lifestyle program to help sarcopenia in older adults

  This program tests a digital, volunteer-supported lifestyle plan to improve muscle health and reduce fall risk in older adults with sarcopenia or frailty.

  Recruiting The University of Hong Kong · Hong Kong · NCT07345832

• Physical performance monitoring for adults being evaluated for kidney transplant

  This project tests whether tracking frailty with the Short Physical Performance Battery (SPPB) before, during, and after kidney transplantation helps predict recovery and outcomes for adults being evaluated for transplant.

  Recruiting University Hospital, Martin · Martin · NCT07338929

• A study on frailty and dependence in older adults

  This study is trying to find out more about frailty in older adults to help doctors spot it early and improve ways to prevent it.

  Recruiting Parc de Salut Mar · Barcelona, Catalonia · NCT06965972

• Cognitive Groove dance program for older adults living with frailty

  This project will test whether Cognitive Groove, a community-based dance rehabilitation program, helps community-dwelling older adults with frailty improve movement, strength, mood, and quality of life compared with usual care.

  Recruiting McMaster University · Hamilton, Ontario · NCT06870149

• Improving care for older patients to prevent disability after hospitalization

  This study tests a new approach to help older patients in the hospital stay strong and healthy after they leave by providing extra support during and after their stay.

  Recruiting University of Milano Bicocca · Monza, Lumbardy · NCT06611228

• Nicotinamide Riboside therapy to slow aging-related decline in frail elderly

  This study is testing if taking nicotinamide riboside can help frail older adults maintain their walking speed and overall health over a year.

  Recruiting Phase 2 Haukeland University Hospital · Bergen, Vestland and 1 other locations · NCT06208527

• Assessing older patients for kidney transplantation

  This study looks at how health and mental well-being assessments can help improve kidney transplant outcomes for older patients.

  Recruiting Institute for Clinical and Experimental Medicine · Prague · NCT06104696

• Cultural adaptation of a frailty assessment tool for hip fracture patients in Greece

  This study is testing a new version of a frailty questionnaire to see if it works well for older Greek patients who have had hip fractures, helping doctors better understand their health needs.

  Recruiting University of Thessaly · Larissa · NCT05091645

• Exercise program for kidney transplant recipients

  This study is testing whether a structured exercise program can help older patients waiting for a kidney transplant improve their physical function and walking ability compared to those who just receive regular care.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04954690

• Using modified stent grafts to treat complex aortic aneurysms in frail patients

  This study is testing if specially designed stent grafts can safely help frail patients with complex aortic aneurysms instead of traditional surgery.

  Recruiting University of Southern California · Los Angeles, California · NCT04524247

• Understanding frailty and pre-frailty in older adults

  This study looks at how common frailty and pre-frailty are in older adults and how heart health relates to these conditions to help improve care for them.

  Recruiting The Opole University of Technology · Opole · NCT04518423

• Measuring Movement and Behaviors in Older Adults

  This study is testing new ways to measure how much older adults move and what kinds of activities they do to better understand their physical health.

  Recruiting University of Castilla-La Mancha · Toledo · NCT04173715

Related topics

Quick answers

How many Frailty Syndrome clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in Iceland (3 trials), Turkey (Türkiye) (2 trials), Spain (2 trials), United States (2 trials), Czechia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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