Interventions to Promote Kidney Transplant Empowerment
Official title: INSPIRE: INterventionS for Promoting kIdney tRansplant Empowerment
Funded at Icahn School of Medicine at Mount Sinai · NIH-11415080 · Data updated 2026-11-12
A targeted program to help adults with kidney disease navigate and complete the steps toward kidney transplant by addressing barriers and streamlining evaluation and waitlisting.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $836,530 |
| NIH project number | 5U01DK137259-04 |
| Project ID | NIH-11415080 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with end-stage kidney disease who are navigating or eligible for kidney transplant evaluation and listing.
✕Less likely to help
Individuals not pursuing transplantation or those not connected to transplant-enabled care pathways may see limited direct benefit.
What this research studies
This project partners with patients, caregivers, clinicians, and dialysis and transplant leaders to develop a multi-level approach that reduces barriers to kidney transplant evaluation and listing. It will use patient interviews and stakeholder input to create practical interventions and evaluation criteria that minimize subjectivity in psychosocial assessments. The team will build on decades of community-engaged research to ensure the interventions fit real-world kidney care settings and improve access to transplantation for eligible adults.
Why it matters
Potential benefit: If successful, patients could experience faster and more equitable access to kidney transplant evaluation and listing, improving treatment options and outcomes.
How similar studies have gone: Past community-engaged research has informed multi-level interventions in health care; this project adapts that approach to kidney transplant pathways.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Chan, Lili — Icahn School of Medicine at Mount Sinai
- Study coordinator: Chan, Lili
Related research
Other NIH-funded projects on the same topics.
-
Microbial clues to diagnose and predict infections in kidney transplant patients
A patient-focused project will look for microbial biomarkers in stool, blood, and urine to help doctors predict and diagnose infections in people who have had a kidney transplant.
-
Immunological mechanisms behind treatment-resistant kidney transplant rejection
This grant explores why certain kidney transplant rejections don’t respond to standard treatments and what immune cells in the graft are driving that resistance.
-
Complement-Bound Exosomes and Kidney Transplant Immunity
This project studies how kidney transplant injury and rejection happen after surgery and whether blocking certain immune pathways during organ preservation could improve transplant outcomes.
-
Blood vessel signals predicting heart problems after kidney transplant
This project studies blood markers and tissue patterns after kidney transplants to identify which patients are at highest risk of cardiovascular problems.
-
Understanding how BK virus links infection to kidney transplant rejection
This project looks at how BK polyomavirus reactivation affects kidney transplant patients and aims to use pre-transplant T cell information to tailor immunosuppression and monitoring.
-
Characterization of a LILRB3 SNP cluster and its link to kidney transplant outcomes
A study in kidney transplant recipients looks at genetic factors that may be tied to higher risk of graft failure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.