Doctor counseling plus smartphone apps to support healthy eating and activity after liver or kidney transplant

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

All participants first receive standardized medical counseling on healthy diet and physical activity and are followed for 12 weeks. After that, participants begin using two personalized smartphone apps (Gamebus and Nutrida) to support behavior change at home while continuing follow-up. Each participant serves as their own comparison, with outcomes before and after starting the apps compared within individuals. The primary focus is feasibility and acceptability (retention, daily app use, and completion of weekly tasks), with secondary measures including diet, physical activity, and body measurements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 60 years
* Liver or kidney transplant received at least 6 months and no more than 25 years prior
* BMI between 21 and 29.9
* Signed informed consent
* Having a personal smartphone
* Stable immunosuppressive therapy in the past 3 months

Exclusion Criteria:

* Significant weight change (\>5% of body weight) in the past 3 months
* Combined liver-kidney transplant
* Medical conditions requiring specific diets that may render adherence to the dietary recommendations of the trial unsafe (e.g., chronic kidney disease, inflammatory bowel disease, celiac disease, bariatric surgery, etc.)
* General physical conditions deemed by the investigator to contraindicate safe participation in any of the trial activities (e.g., blindness, vertebral fractures, wheelchair dependence, home oxygen therapy, etc.)
* Adherence to specific dietary regimens for ethical and/or religious reasons that are incompatible with the dietary recommendations of this trial
* Active malignant tumors currently under pharmacological treatment or awaiting surgical treatment (except cutaneous squamous cell carcinomas), or history of malignant tumors within the last 5 years, except for hepatocellular carcinoma
* Psychiatric comorbidities deemed by the investigator to potentially compromise safety and/or adherence, thereby risking biasing the results (e.g., schizophrenia, bipolar disorder, eating disorders, etc.)
* Changes in glucose-lowering or lipid-lowering therapy during the 90 days prior to the enrollment visit
* Active participation in another research or non-research program aimed at lifestyle modification
* Any clinical condition, diagnosed or under diagnostic evaluation, that the investigator considers may compromise safety and/or a priori adherence to the intervention, with a potential risk of altering the study outcomes

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Bo, Italy Recruiting

Study contacts

• Study coordinator: Lucia Brodosi, MD
• Email: lucia.brodosi@aosp.bo.it
• Phone: +39 3285524214

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.