Evaluating outcomes of kidney transplant patients with thrombotic microangiopathy
Post-transplant Thrombotic Microangiopathy: Evaluation of Outcomes at the Bologna Kidney Transplant Centre
This study looks at how common a condition called post-transplant thrombotic microangiopathy is in kidney transplant patients and how it affects their recovery and overall health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, BO) |
| Trial ID | NCT06759961 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the incidence of post-transplant thrombotic microangiopathy (PT-TMA) among kidney transplant recipients at the Bologna Kidney Transplant Centre. It involves the systematic collection of clinical data from patients diagnosed with PT-TMA, starting from June 1, 2016, and will continue for 10 years following ethical approval. The study will analyze the relationship between PT-TMA and renal transplant outcomes, utilizing both retrospective and prospective data collection methods.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who have received a kidney transplant from various donor types.
Not a fit: Patients who are not kidney transplant recipients or those under 18 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of PT-TMA and improve management strategies for kidney transplant patients.
How similar studies have performed: While there may be studies on thrombotic microangiopathy, this specific evaluation in the context of kidney transplants is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Living kidney transplant recipient, brain death cadaver donor, cardiac death cadaver donor, single kidney transplant, double kidney transplant, combined kidney transplant * Acquisition of Informed Consent to participate in the study and to process personal, special and genetic data Exclusion Criteria: \-
Where this trial is running
Bologna, BO
- IRCCS Sant'Orsola University Hospital - Nephrology, Dialysis and Transplant Unit — Bologna, Bo, Italy (Recruiting)
Study contacts
- Principal investigator: Giorgia Comai, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Marcello Demetri, Biology
- Email: marcello.demetri2@unibo.it
- Phone: 00393349549878
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.