Investigating how hyperthyroidism affects kidney transplant outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between thyroid function changes in the immediate post-transplant period and the prognosis of kidney transplants. It will assess renal function, medical complications, and patient survival three months after transplantation. The study will also identify risk factors for thyroid disorders that may arise shortly after the transplant. By analyzing clinical and laboratory data, researchers hope to understand how immunosuppressive therapies and surgical stress impact thyroid hormone levels in kidney transplant patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects transplanted at our Center;
* Subjects whose 3-month follow-up is available;
* Age ≥18 years;
* Availability of clinical and laboratory data regarding thyroid function trends in the immediate post-transplant period (within 30 days after transplantation);
* Subjects giving informed consent to participate.

Exclusion Criteria:

* None.

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Bo, Italy Recruiting

Study contacts

• Principal investigator: Gaetano La Manna, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Gaetano La Manna, MD
• Email: gaetano.lamanna@unibo.it
• Phone: +39 051 214 4577

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• New method for diagnosing acute rejection in kidney transplants

  This study is testing a new way to diagnose acute rejection in kidney transplants by using a special test on urine to help tailor treatments for better recovery.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06801262

• Preventing CMV after receiving a CMV-positive donor kidney using daily antiviral pills or weekly blood monitoring

  This study will test whether taking daily antiviral pills for 200 days or doing weekly blood checks and treating only if the virus appears is better at preventing CMV disease in adults who get a kidney from a CMV-positive donor and are themselves CMV-negative.

  Recruiting at 6 sites Phase 3 University of California, San Francisco · San Francisco, California and 7 other locations · NCT06798909

• ETHY-001 safety and activity in Thyroid Eye Disease (TED)

  This study tests ETHY-001 versus placebo to see if it is safe, tolerable, and shows activity in people with thyroid eye disease.

  Recruiting at 2 sites Phase 1 Ethyreal Bio, Inc. · Orland Park, Illinois and 2 other locations · NCT07885605

• Omnisol-preserved kidneys before transplant (hypothermic machine perfusion)

  This study tests whether using Omnisol during hypothermic machine perfusion before kidney transplant can improve early graft function compared with standard preservation.

  Recruiting Vivalyx GmbH · Rotterdam · NCT07792317

• How Propofol and Sevoflurane Affect miRNA in Living Kidney Donors

  This study tests whether using propofol or sevoflurane during donor nephrectomy changes levels of miRNAs in living kidney donors.

  Recruiting University of Gaziantep · Gaziantep, Sahinbey · NCT07760402

• Can a smart wristband help guide levothyroxine dosing after total thyroidectomy

  This study tests whether nighttime heart rate and rhythm data from a wearable can hint if levothyroxine dose is too high or too low before the usual blood tests.

  Recruiting Yeditepe University Hospital · Istanbul, Kadıköy · NCT07733375

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.