Investigating how hyperthyroidism affects kidney transplant outcomes
Hyperthyroidism in the Immediate Post-kidney Transplantation Period: a Potential Predictive of Worse Outcome of Renal Graft
This study looks at how changes in thyroid function right after a kidney transplant can affect recovery and overall health for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, BO) |
| Trial ID | NCT06794203 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between thyroid function changes in the immediate post-transplant period and the prognosis of kidney transplants. It will assess renal function, medical complications, and patient survival three months after transplantation. The study will also identify risk factors for thyroid disorders that may arise shortly after the transplant. By analyzing clinical and laboratory data, researchers hope to understand how immunosuppressive therapies and surgical stress impact thyroid hormone levels in kidney transplant patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have undergone kidney transplantation at the participating center and have available follow-up data.
Not a fit: Patients who have not undergone kidney transplantation or those without available thyroid function data post-transplant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management of kidney transplant patients by identifying thyroid function as a predictive factor for transplant outcomes.
How similar studies have performed: While the specific association between hyperthyroidism and kidney transplant outcomes is less explored, similar studies have shown that thyroid function can impact various health outcomes, suggesting potential relevance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects transplanted at our Center; * Subjects whose 3-month follow-up is available; * Age ≥18 years; * Availability of clinical and laboratory data regarding thyroid function trends in the immediate post-transplant period (within 30 days after transplantation); * Subjects giving informed consent to participate. Exclusion Criteria: * None.
Where this trial is running
Bologna, BO
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, Bo, Italy (Recruiting)
Study contacts
- Principal investigator: Gaetano La Manna, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Gaetano La Manna, MD
- Email: gaetano.lamanna@unibo.it
- Phone: +39 051 214 4577
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.