Sponsor or institution
Clinical trials and research at University of Florida
As of November 12, 2026, Find a Trial lists 153 clinical trials run by University of Florida that are recruiting, at sites in 3 countries (most in United States (151), Haiti (1), Lebanon (1)). By phase: Phase 2 (19), Phase 4 (10), Phase 1/2 (6), Phase 1 (5). There are also 1,249 NIH-funded research projects at this institution, with $632.1 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 153Clinical trials
- 1249NIH research projects
- 3Countries
Newest trials
All recruiting trials (newest 150 of 153)
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Two-Door Doulas: Enhanced vs Standard Medicaid Doula Care in Pregnancy
This trial tests whether an enhanced, earlier, and more frequent doula support program helps pregnant people on Medicaid feel less depression and anxiety after birth compared with the standard Medicaid doula care in Florida.
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Just-in-Time Coping Prompts for College Students
We’re testing whether sending brief coping tips at moments of emotional shift can influence how college students react online, drink, or eat when feelings spike.
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Momentary Coping Prompts and Hair Steroids in College Students
This trial tests whether sending brief coping prompts at moments of emotional volatility helps college students respond to emotions, while collecting hair samples to see if long-term stress hormones relate to those responses.
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VM100: a nutritional supplement to see if it improves quality of life for boys with Duchenne
This Phase 2 study tests VM100, a nutritional drink, in boys aged 8 and up with Duchenne muscular dystrophy to see if it can improve quality of life and reduce fatigue.
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Muscle health before and after lung transplant in adults
This study tests how respiratory and leg muscle health relates to physical function and recovery in adults awaiting and after lung transplantation.
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Acute intermittent hypercapnia-based interventions for upper airway and axial control in Parkinsonism
This randomized pilot study tests whether a single session of acute intermittent hypercapnic hypoxia or hypercapnic normoxia can improve upper airway and axial motor function in adults with Parkinsonism.
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Alcohol sensitivity in healthy adults aged 65–80 who drink
This study tests how older adults who regularly drink respond to a moderate amount of alcohol, to see how their cognition and brain activity may change.
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Iron infusion and MRI to study inflammation in HFpEF
A small early-phase study tests whether an iron infusion affects heart inflammation in people with HFpEF, using MRI measures before and after treatment.
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Bio Leg: Advancing Mobility for people with above-knee amputations
This study tests whether the Bio Leg powered knee improves walking function for people who already use a C-leg after an above-knee amputation.
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Universal immunization to boost immunotherapy response in advanced NSCLC
This study tests whether giving the Pfizer COVID-19 mRNA vaccine in combination with frontline pembrolizumab and chemotherapy helps more patients with stage IV NSCLC respond to treatment.
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IL-8 receptor–modified CAR T cells for brain metastases in adults
This phase 1 study tests whether patient-derived, IL-8 receptor–modified CD70 CAR T cells can be safely given to adults with brain metastases.
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Short-term supraspinatus tendon changes after two shoulder exercise sessions.
This study will test whether two different 15-minute shoulder exercise programs cause short-term tendon changes in adults with and without shoulder pain.
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Project HOPEFUL: 8-week warm-calling program for homebound older adults
This project tests whether 8 weeks of friendly 20–30 minute phone calls from trained helpers can reduce loneliness, suicidal thoughts, and improve social connection and quality of life for homebound older adults who receive aging services.
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Early normobaric hyperoxia for traumatic cervical or thoracic spinal cord injury
This study tests whether giving short, repeated sessions of 100% oxygen to people on ventilators after recent traumatic cervical or thoracic spinal cord injuries helps their recovery.
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Daily cranberry juice to boost stress resilience during multitasking
This will test whether 70 days of daily cranberry juice helps healthy adults aged 30–55 stay calmer and perform better on thinking and motor tasks when multitasking.
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Prefrontal intermittent theta burst stimulation for thinking problems after ICU delirium
This trial will test whether intermittent theta burst brain stimulation can safely improve thinking, memory, and attention in older adults who had delirium during an ICU stay.
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MEG to track brain changes after focused ultrasound for essential tremor
This project uses MEG and MRI to see how high‑intensity focused ultrasound (HiFU) changes brain activity in people aged 50–84 with essential tremor who haven't responded to at least two medications.
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Rehabilitation to protect the diaphragm before mechanical ventilation.
This study will test whether a single session of inspiratory strength training or noninvasive spinal stimulation helps healthy adults keep diaphragm strength before a short period of mechanical ventilation.
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ECHO Diabetes program for Federally Qualified Health Centers
This program will test whether a 6-month tele-education series for primary care teams at Federally Qualified Health Centers helps lower very high HbA1c rates and increases use of diabetes technology in adults with diabetes.
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Patterned deep brain stimulation delivered at home for Parkinson's
This study will test whether three types of patterned deep brain stimulation can be used safely and comfortably at home in people with Parkinson's who already have stable bilateral STN or GPi Boston Scientific DBS systems.
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Managing complications from distal shoe space maintainers
This project will collect routine treatment data to see how often and why soft tissue problems happen in children ages 3–9 who receive distal shoe space maintainers after losing a primary second molar.
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See if three months of visual flicker at 16.67 Hz helps cognition and mood in older adults with or without subjective cognitive concerns
This study tests whether three months of flicker stimulation three times a week can improve thinking, movement, and mood in healthy older adults and those with subjective cognitive decline.
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Eat Right, Screen Right — nutrition and screening guidance to lower colorectal cancer risk
This online program tests whether six tailored lessons help adults learn about nutrition-related risks and screening choices to lower colorectal cancer risk.
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Wearable focal vibration to improve arm and hand function in relapsing-remitting MS
This pilot will try a home-based wearable focal vibration device on arm muscles to see if it improves arm and hand function in adults with relapsing-remitting multiple sclerosis.
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Five-week Telehealth Cognitive Training for Mild Cognitive Impairment
A five-week, at-home, telehealth program tests whether a shorter cognitive training works as well as the original eight-week version for people with mild cognitive impairment.
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Improving Cervical Cancer Prevention for Women with Chronic Conditions
We’re testing PINPOINT, a patient-navigation and self-collection approach, to see if it helps women with obesity or type 2 diabetes who aren’t up-to-date with cervical cancer screening get screened.
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Brain-signal guided DBS programming for Parkinson's
This study will test whether using brain signals recorded from your Percept DBS device (beta power or a broad-band algorithm) can pick stimulation settings that work as well or better than standard clinician programming for people with Parkinson's.
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Interposed Nucleus aDBS for Ataxia in SCA6
A small, single-center study will try a cerebellar adaptive deep brain stimulation approach to help adults with Spinocerebellar Ataxia type 6.
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Digitally delivered obesity prevention for parents in home visiting programs
A digital program for mothers in home visiting is tested to see if it helps prevent obesity in their infants and improve parenting practices.
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Cangrelor dose adjustment using platelet testing for patients awaiting coronary procedures
This trial tests whether adjusting the cangrelor infusion based on platelet-function testing keeps platelet reactivity in the target range for adults with coronary artery disease awaiting coronary procedures.
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POSLUMA PET-CT to improve detection of significant prostate cancer in PIRADS 2/3 lesions
This test will see if POSLUMA (18F-rhPSMA-7.3) PET-CT can better find clinically significant prostate cancer in men with uncertain PIRADS 2 or 3 MRI results who are scheduled for a targeted biopsy.
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Blood and cervical HPV DNA/RNA testing to track treatment response in cervical cancer
This 9-month study will test two blood-based HPV tests (NavDx and Quantivirus) to see if they can track how adults with HPV-related cervical cancer respond to surgery, radiation, and chemotherapy.
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Noninvasive ear stimulation to improve hearing speech in noisy places
This will test whether gentle electrical stimulation of the ear can help people with traumatic brain injury hear speech more clearly in noisy environments.
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Pre-surgery exercise program to improve internal rotation after reverse shoulder replacement
A 6-week pre-surgery exercise program that tries to help people getting a reverse shoulder replacement improve internal rotation by strengthening and mobilizing the shoulder girdle.
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Adding zinc to Botox for cervical dystonia
This will test whether taking daily zinc citrate after a Botox injection helps people with cervical dystonia keep symptom relief longer.
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Living Independently with Functional Training
This six-week hybrid home- and clinic-based task-oriented resistance exercise program tests whether recently discharged older adults with mobility limitations and mild cognitive impairment can improve daily function and mobility.
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Adding a GLP‑1 weight‑loss medicine to a levonorgestrel IUD for obese patients with endometrial precancer or low‑grade cancer
This Phase 2 trial will test whether giving a GLP‑1 weight‑loss medicine together with a levonorgestrel IUD helps obese adults with endometrial intraepithelial neoplasia or grade 1 endometrioid cancer who cannot or do not want a hysterectomy.
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Parathyroid removal to improve mobility in older adults
This project will see if removing an overactive parathyroid gland helps adults aged 60+ with primary hyperparathyroidism regain strength, move better, and be more active.
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Urine extracellular vesicle biomarkers for people with low magnesium
We will test whether tiny particles in urine can reveal the kidney-related causes of low blood magnesium in adults with hypomagnesemia.
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Florida ASCENT Program
This project will test whether combining the MyCarePulse EHR platform with ASCENT patient navigators helps adults with recent cancer diagnoses in Florida improve food security, diet quality, and confidence in healthy eating compared with standard care.
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How deep brain stimulation affects speech and swallowing in Parkinson disease
This study will test whether deep brain stimulation to the subthalamic nucleus (STN) or globus pallidus interna (GPi) changes voice, speech, swallowing, and cough in people with idiopathic Parkinson disease who are approved for first-time DBS surgery.
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Switching from clopidogrel to low-dose prasugrel after PCI in people at high bleeding and ischemic risk
We will test whether switching adults who had PCI and are at both high bleeding and ischemic risk from standard-dose clopidogrel to low-dose prasugrel lowers platelet reactivity compared with staying on clopidogrel.
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Great toe strength in people with chemotherapy-induced peripheral neuropathy
This research tests whether a small device called ToeScale can measure great toe strength in adults with CIPN and in matched healthy adults.
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Short low-oxygen breathing sessions to help early breathing recovery after spinal cord injury
This study will test whether two types of brief low-oxygen breathing sessions can improve breathing strength and airway defense in people 2 weeks to 6 months after a spinal cord injury.
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Compassion Strikes Back — support for LVAD patients and their caregivers
This project tests whether brief informational handouts or a short meeting with a psychologist can help adult LVAD patients and their primary family caregivers feel less stressed and improve quality of life during the first two months after hospital discharge.
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Subcutaneous Lasix ONYU for at-home treatment of worsening heart failure
This test will see if giving Lasix through a small subcutaneous device at home relieves fluid overload in adults with worsening heart failure.
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Two-week gratitude journaling for temporomandibular (jaw) pain and overlapping chronic pain.
This study will see if two weeks of gratitude journaling helps adults with TMD and other chronic overlapping pain feel less pain and have less disruption in daily life.
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Restoring foot sensation to improve walking and multitasking
This project will test whether a wearable leg sensory device called Walkasins helps older adults with reduced foot sensation walk more automatically, with steadier gait and less thinking when doing another task.
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How deep brain stimulation affects walking adaptation and freezing in Parkinson's
This test will see if turning deep brain stimulation on helps people with Parkinson's adapt their walking and reduce freezing while walking on a split-belt treadmill off medication.
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Cavity marking technique to improve radiotherapy planning after breast-conserving oncoplastic surgery
This will test a new cavity-marking method to help radiation teams plan treatment more accurately for adults having breast-conserving surgery with oncoplastic reconstruction.
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Blood flow restriction training for shoulder pain
This study is testing if a new training method that restricts blood flow can help people with shoulder pain feel better and improve their strength during physical therapy.
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Tocilizumab-aazg to reduce stroke risk after a ruptured brain aneurysm
This trial will try to see if a single IV dose of tocilizumab-aazg is safe and can help prevent delayed strokes in adults who have had a ruptured brain aneurysm (aneurysmal subarachnoid hemorrhage).
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How weight-loss surgery and vagal nerve stimulation affect thinking and the brain
We will test whether weight-loss surgery and a 30-day at-home vagal nerve stimulation (tVNS) treatment improve thinking and brain function in adults with obesity and diabetes.
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Scalable tobacco-cessation support for cancer survivors and their caregivers
This project will try a tailored tobacco-cessation program plus provider training to help cancer survivors and their caregivers quit using tobacco.
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Exploring the benefits of Parent-Child Interaction Therapy
This study is trying to see if Parent-Child Interaction Therapy can help parents and their young children with behavior issues feel less stressed and improve their emotional well-being.
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Comparing two methods of reducing antiplatelet therapy in heart patients
This study is testing two ways to safely lower blood-thinning medication in heart patients after a procedure to see if one method works just as well as the other.
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Using visual cues to improve balance training
This study is testing if special goggles that change what you see can help young and older adults improve their balance while walking on a balance beam.
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Study on physical and cognitive aging in older Hispanic adults
This study is trying to see how physical activity and thinking skills change over time in older Hispanic adults to understand aging better.
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Listening to calming music for health benefits
This study is testing if listening to calming music can improve health and well-being by looking at how it affects heart rate and stress levels in participants.
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Comparing ticagrelor and prasugrel for heart disease treatment
This study is testing whether ticagrelor or prasugrel is better at preventing bleeding and heart issues in patients with heart disease who have already been on another type of treatment.
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Nighttime-adaptive deep brain stimulation for essential tremor
We will test whether using each patient’s thalamic sleep-related brain signals to automatically turn DBS off at night can reduce side effects while keeping tremor under control in people with essential tremor who already have Medtronic Percept implants.
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Alpha/beta T‑Cell and B‑Cell Depletion plus Zoledronic Acid for Pediatric and Young Adult Solid Tumors
This study will try removing alpha/beta T cells and B cells from donor stem cell grafts and giving zoledronic acid to see if it helps children and young adults (6 months to 25 years) with relapsed or high‑risk solid tumors tolerate allogeneic transplant and reduce relapse.
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Understanding how trauma affects the gut and bone marrow
This study looks at how stress and inflammation after a major trauma affect the gut and bone marrow to see if they contribute to ongoing anemia and recovery issues in trauma survivors.
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Patient and therapist beliefs about spinal manipulation and physical therapy for low back pain
This will see if patients' and their physical therapists' thoughts and beliefs change how much people with chronic low back pain improve from physical therapy that may include spinal manipulation, exercise, and education.
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Comparing antiplatelet therapies after heart procedures
This study is testing whether a new way of managing blood-thinning medications after heart procedures can help people with heart issues avoid problems while also reducing the risk of bleeding.
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Evaluating a new treatment approach for recurrent glioblastoma
This study is testing a new combination treatment for adults with recurrent glioblastoma to see if using Optune GIO®, laser therapy, and a drug called pembrolizumab together can help manage their cancer better.
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Adding polyphenol-rich pulses to your daily diet to improve skin health
This 12-week test will see if adding a daily serving of polyphenol-rich pulses improves skin health in women aged 45–65.
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Improving HPV vaccination rates in rural communities
This study is testing different ways to help parents in rural North Central Florida get their kids aged 9 to 12 vaccinated against HPV to see if it can improve vaccination rates.
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Improving balance and walking in older adults using spinal stimulation
This study is testing if combining spinal stimulation with balance training can help older adults improve their balance and walking to reduce the risk of falls.
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Combining T Cell Therapy and Vaccines with Immune Blockade for Medulloblastoma
This study is testing a new treatment that combines special immune cell therapy and vaccines to see if it can help children and young adults with recurring medulloblastoma feel better.
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Near-infrared sensors and intramuscular glucose checks to detect poor blood flow in a fractured leg
This study tests whether skin NIRS sensors and a muscle glucose measurement can detect reduced perfusion in adults with a tibial fracture and suspected compartment problems.
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Culturally tailored pain management for Black elders
This study is testing a new pain management program designed specifically for Black elders with chronic pain to see if it helps them feel better and manage their pain more effectively.
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Vestibular brain stimulation to improve gait and navigation in older adults with subjective cognitive decline
Researchers will test whether bilaterally stimulating vestibular cortex with tDCS while walking and doing tasks can improve brain network segregation and walking/navigation in older adults who report cognitive decline.
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Using Gemcitabine and Docetaxel to Treat Low Grade Bladder Cancer
This study is testing if giving gemcitabine and docetaxel directly into the bladder can help people with low-grade bladder cancer have fewer recurrences of their disease.
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Nicotine cessation program for women with breast cancer needing reconstruction
This study tests a program to help women with breast cancer quit smoking before their surgery to see if it can improve their recovery and overall health.
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Targeted low-dose ATG with optional verapamil for recent-onset type 1 diabetes
This trial will test whether giving targeted low-dose anti-thymocyte globulin (ATG), followed by or without verapamil, helps people aged 6–35 with recent-onset type 1 diabetes preserve their own insulin production.
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Using genetic testing to improve emergency care
This study is testing if using genetic testing in emergency rooms can help doctors choose better treatments and reduce the number of times patients need to come back.
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Measuring heat from blue versus red dental curing lights during restorations
This trial will see if red dental curing light causes less heat and less post-operative sensitivity than the standard blue light for people receiving restorative dental procedures.
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Using CBD to treat knee osteoarthritis pain
This study is testing if CBD can help relieve knee pain for adults with osteoarthritis who are struggling with moderate to severe discomfort.
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Using focused ultrasound to treat localized prostate cancer
This study tests whether focused ultrasound treatment can help men with localized prostate cancer that has come back after radiation feel better and improve their quality of life compared to traditional treatments.
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Helping ED providers manage non‑traumatic dental pain
This project will test a clinical decision support tool and interviews with full‑time emergency department clinicians to see if they can reduce unnecessary opioid and antibiotic prescriptions and ED revisits for people with non‑traumatic dental pain.
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Evaluating a new method of lymphatic drainage for breast cancer patients
This study is testing if a new way of using lymphatic drainage, guided by a special dye, can help breast cancer patients avoid swelling after surgery.
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Combining exercise and tadalafil for treating Duchenne muscular dystrophy
This study is testing if combining exercise with a medication called tadalafil can help boys with Duchenne muscular dystrophy improve their muscle function and blood flow.
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Using mobile health data to improve recovery after bypass surgery for leg ischemia
This study is testing if using health data from a smartwatch can help older patients recover better and move more easily after bypass surgery for leg problems.
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Improving patient instructions for first-time radiotherapy
This study is testing whether clearer instructions for first-time radiotherapy patients can help them feel more comfortable and involved in their treatment.
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Effects of minocycline on blood pressure in resistant hypertension
This study is testing if the antibiotic minocycline can lower blood pressure in people who have high blood pressure that doesn't respond to usual treatments, and whether the results differ by race.
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Comparing low-dose ticagrelor and clopidogrel in heart patients undergoing procedures
This study is testing if a lower dose of ticagrelor can help heart patients with high platelet activity have fewer complications during and after a procedure compared to clopidogrel.
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Evaluating the effects of different massage techniques on neck pain relief
This study is testing whether different types of massage or cold water can help people with neck pain feel better and if their sensitivity to pain affects how much relief they get.
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Decision tool for selecting women for bladder surgery
This study is testing a new decision-making tool to help doctors choose which women with bladder cancer can safely have surgery without losing their reproductive organs.
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Managing Low Back Pain for Horticulture Workers
This study is testing two different ways to help nursery and landscape workers manage their low back pain, one with extra personalized support and the other with just self-management videos, to see which works better.
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Training dental teams to improve interactions with young children
This project will test a day-long workshop that teaches dentists and dental staff behavior-management skills to help children ages 2–10 feel less scared and cooperate better during dental visits.
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Using Fluoxetine right after injury to help trauma victims recover better
This study is testing if giving Fluoxetine right after an injury can help trauma victims avoid PTSD and depression while also looking at pain levels and opioid use.
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Breathing treatment for recovery after spinal cord injury
This study is testing if a new breathing treatment can help people with spinal cord injuries recover their breathing and movement better than a standard treatment.
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Pterygopalatine fossa nerve block for headaches after subarachnoid hemorrhage
This study is testing if a special nerve block can help people who have had a brain bleed feel better by reducing their headaches.
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Standardized oral care using human milk for premature infants in the NICU
This study is trying to see if giving regular oral care using human milk can help very low birth weight babies in the NICU stay healthier and avoid complications.
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Investigating brain stimulation effects on memory in older adults with mild cognitive impairment
This study is testing if a type of brain stimulation can help improve memory in older adults with mild cognitive impairment compared to those without memory issues.
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Virtual physical therapy support for runners recovering from injuries
This study tests whether adding virtual physical therapy sessions to regular home exercises can help runners aged 18 to 65 recover better from chronic lower body injuries.
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Using light therapy to relieve pain from jaw disorders
This study is testing whether light therapy can help relieve pain for people suffering from jaw disorders like temporomandibular disorders (TMD).
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Using Transcranial Pulse Stimulation to Enhance Brain Function
This study is testing if a new brain stimulation technique can improve thinking and memory in older adults, including those with mild dementia.
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Understanding immune function in type 1 diabetes
This study looks at how certain genes linked to type 1 diabetes affect the immune system and its role in causing the disease.
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Exercise program for breast cancer survivors
This study tests whether a rowing exercise program can help breast cancer survivors improve their heart health after finishing treatment.
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Cognitively engaging walking exercise and brain stimulation for older adults
This study is testing if combining brain stimulation with fun walking exercises can help older adults with mild to moderate cognitive decline improve their thinking and walking skills.
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Using kava to help people quit smoking and manage stress and sleep issues
This study is testing if taking kava can help people who smoke quit smoking while also reducing stress and improving sleep.
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Depleting specific immune cells in stem cell transplants for blood cancers
This study is testing if removing certain immune cells during stem cell transplants can help children and young adults with blood cancers have better outcomes and fewer complications.
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Comparing two surgical methods for treating distal femur fractures
This study is testing which of two surgical methods works better for helping older patients recover from specific knee fractures after they've had knee replacement surgery.
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Breathing and attention training for managing fibromyalgia pain
This study is testing whether breathing and attention training can help people with fibromyalgia manage their pain better.
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Using oxytocin to reduce pain and opioid abuse in older adults
This study is testing if giving oxytocin with oxycodone can help older adults feel less pain and reduce the risk of misusing the opioid.
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Using mobile video to help young heart transplant patients take their medications
This study tests whether using mobile videos can help young heart transplant patients remember to take their medications regularly.
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Walking exercise to reduce fatigue in older breast cancer survivors
This study is testing whether two types of walking exercises can help older women who have survived breast cancer feel less tired.
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Using AI to personalize drug dosing for liver cancer treatment
This study is testing whether using artificial intelligence to personalize drug doses can help people with liver cancer get better treatment with fewer side effects.
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Investigating how exercise affects brain and movement in dystonia patients
This study is testing if a structured exercise program can improve movement and brain function in people with focal cervical dystonia who haven't had much success with other treatments.
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Connecting Black and Hispanic adults with cancer to clinical trials using a culturally tailored online portal
This project tests whether a tailored online portal with virtual community health educators can help Black and Hispanic adults with cancer find and get referred to cancer clinical trials.
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Phone-based support for quitting smoking in Lebanon
This study is testing different ways to help people in Lebanon quit smoking, including phone support and nicotine patches, to see which method works best.
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Understanding blood changes after severe trauma
This study looks at how severe injuries affect blood and bone marrow in trauma patients to see if it changes their immune response compared to patients having planned hip surgeries.
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Using transcutaneous vagal nerve stimulation to improve therapy for OCD
This study is testing if adding a new treatment called transcutaneous vagal nerve stimulation to therapy can help adults with obsessive-compulsive disorder feel better.
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Improving nighttime healthcare access for children in Haiti
This study is testing a new telemedicine service called MotoMeds to see if it can help children in Haiti get better nighttime healthcare for their illnesses.
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Training older adults to improve trust-related decision making
This study is testing whether training older adults with neurofeedback can help them make better trust-related decisions, especially those dealing with neurodegenerative diseases like Alzheimer's.
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Comparing mobile health approaches for quitting smoking in underserved patients
This study is testing three different ways to help underserved adults quit smoking to see which one works best for them.
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Improving cervical cancer screening for underserved women
This study is testing if personalized cervical cancer screening options and support can help underserved women get the screenings they need.
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Breathing exercises before joint surgery
This study is testing if breathing exercises before joint surgery can help patients breathe better after their operation and avoid complications.
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Investigating gut microbiome changes in sepsis and trauma survivors
This study is trying to see how changes in gut bacteria affect recovery in people who survived sepsis or severe trauma, including those with traumatic brain injuries.
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Media-focused parenting program to prevent teen substance use
This program tests whether a web-based T.E.C.H. Parenting course helps parents of middle-schoolers reduce their children's exposure to substance-use portrayals in media and lower their risk of starting substance use.
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Identifying patients at risk of heart attack during elective PCI
This study is testing a new scoring system to see if it can help identify patients with stable heart disease who are at risk of having a heart attack during a specific heart procedure called PCI.
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Engineered donor graft for pediatric blood cancer treatment
This study is testing a new type of donor graft called Orca-Q to see if it can help children with blood cancers do better after a stem cell transplant.
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Understanding pain processing in fibromyalgia and rheumatoid arthritis
This study is trying to understand how people with fibromyalgia and rheumatoid arthritis experience pain in similar ways to help improve treatment options.
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Reducing chemotherapy and radiation for certain throat cancers
This study is testing a lighter treatment plan for certain throat cancers to see if it can work just as well as stronger chemotherapy and radiation while causing fewer side effects.
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Reducing alcohol use among people living with HIV using mobile health tools
This study is testing if using mobile health tools can help people living with HIV cut down on their alcohol use.
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Using AI and sensors to monitor critically ill patients in the ICU
This study is testing whether using AI and sensors can help doctors better monitor and understand the health of critically ill patients in the ICU.
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Investigating immune responses in surgical sepsis patients
This study is trying to understand how certain immune cells behave in patients with surgical sepsis to see if it affects their recovery and risk of infections later on.
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Cognitive and gut health interventions for alcohol users with HIV
This study tests two different approaches to help people with HIV who drink alcohol by using a device to stimulate the nervous system and a probiotic to improve gut health and brain function.
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Examining how different terrains affect foot muscle strength in healthy people and those with plantar fasciitis
This study is testing how walking on different types of surfaces affects foot muscle strength in healthy people and those with plantar fasciitis.
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Using Epidiferphane to Reduce Side Effects of Taxane Chemotherapy in Breast Cancer Patients
This study is testing if a new drug called Epidiferphane can help breast cancer patients feel better by reducing the side effects of their chemotherapy treatment.
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Combining Atezolizumab and Tivozanib for Treating Certain Cancer Types
This study is testing a new combination of two cancer drugs, Atezolizumab and Tivozanib, to see if they can help people with tough-to-treat cancers like bile duct, gallbladder, breast, and neuroendocrine tumors.
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Precision medicine and cell therapy for children with brain and neuroblastoma cancers
This study is testing a new treatment that combines targeted therapy with immune cell therapy to see if it helps children with tough brain cancers like DIPG and neuroblastoma.
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RNA-lipid particle vaccines for treating newly diagnosed brain tumors in children and adults
This study is testing a new type of vaccine made from RNA to see if it can safely help adults and children with newly diagnosed brain tumors feel better after their treatment.
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Low-dose pioglitazone for treating liver disease in diabetes patients
This study is testing if a low dose of pioglitazone can improve liver health in people with type 2 diabetes and a specific liver condition called NASH.
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Alcohol and sexual health education for young men
This study is testing whether different types of education on alcohol and sexual health can help young men stay safe from alcohol-related problems and STIs while they use a preventive HIV medication.
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Evaluating the effects of oxytocin on pain relief and opioid use
This study is testing if oxytocin can make oxycodone work better for pain relief and help reduce the chances of misuse for people who need pain management.
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New approach to control severe essential tremor using advanced brain stimulation
This study is testing a new brain stimulation device to see if it can better control severe tremors in people who haven't found relief with standard treatments.
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Using a device to reduce reflux in lung transplant patients
This study is testing whether the Reflux Band™ device can help lung transplant patients manage their acid reflux symptoms better.
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Non-invasive nerve stimulation to improve sleep in PTSD and TBI patients
This study is testing two types of nerve stimulation to see if they can help veterans with PTSD and mild brain injuries sleep better.
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Evaluating the clinical utility of Endoscopic Submucosal Dissection
This study looks at how helpful Endoscopic Submucosal Dissection is for patients who are already scheduled to have the procedure as part of their regular medical care.
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Using melatonin to protect the brain in newborns with HIE during cooling treatment
This study is testing whether melatonin can help protect the brains of newborns with Hypoxic-Ischemic Encephalopathy during cooling treatment to see if it improves their long-term development.
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Understanding how trauma affects blood stem cells in elderly patients
This study looks at how severe trauma affects blood stem cells in older patients to see if it changes their recovery and risk of infections compared to those who haven't been injured.
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Characterizing cardiac and neuromuscular performance in Friedreich's Ataxia patients
This study is trying to see how Friedreich's Ataxia affects heart and muscle function in patients compared to healthy people, using advanced tests to learn more about the condition.
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Measuring tissue oxygen levels in children with heart failure
This study is testing how oxygen levels in the tissues of children with heart failure compare to healthy kids to see if these levels change with their condition.
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Effects of a Ketogenic Diet on Seizures in Children
This study tests if a ketogenic diet can help children with seizures who don't respond well to regular treatments by looking at how it affects their seizure frequency and medication needs.
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Investigating how lung diseases affect white blood cells in the lungs
This study is trying to see how Alpha-1-antitrypsin deficiency and Cystic Fibrosis affect important white blood cells in the lungs, which could help us understand lung inflammation and disease better.
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Using MRI and biomarkers to monitor muscular dystrophy progression
This study is testing if MRI and other tests can help track how Duchenne and Becker muscular dystrophies change over time in boys and men, and see how these changes relate to their daily activities and treatments.
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Collecting brain tumor tissue samples for future research
This study is collecting leftover brain tumor samples and related information to help researchers find better treatments and cures for brain tumors in the future.
Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.
NIH-funded research (newest 40 of 1249)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Mitochondrial pores and muscle loss in cancer cachexia
A small US-based study will explore how changes in mitochondria contribute to muscle wasting in people with cancer cachexia and how this may be slowed.
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Photobiomodulation for jaw pain from TMD
A clinician-scientist at the University of Florida is testing a light-based therapy to help adults with temporomandibular disorder pain feel better and jaw function improve.
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How the brain controls swallowing and airway protection
A research team at the University of Florida is studying how brain networks control swallowing to reduce risk of choking and lung infections in people with neuromuscular diseases.
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Donor-driven 3D organoid platform to study pancreatic cancer drug response
A pilot project to create patient-derived, 3D organoid models of pancreatic cancer to measure how tumors from different people respond to chemotherapy.
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RAAS inhibitors and pancreatic cancer risk in diverse adults
A Florida-based study will look at whether commonly used blood pressure medicines (RAAS inhibitors) are linked to new cases of pancreatic cancer, especially among Black and Hispanic adults.
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Pilot project exploring new cancer drugs for pancreatic cancer in African American patients
A small, early-stage project tests new drug-derived compounds to treat pancreatic cancer, focusing on African American patients who are disproportionately affected.
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Sex chromosomes and beta-cell function in type 2 diabetes
This NIH grant studies how sex differences at the chromosome level affect insulin-producing pancreatic cells in adults with type 2 diabetes, with the goal of guiding personalized treatments.
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Understanding how aging and Alzheimer’s affect how people make tough choices
This NIH grant studies how aging and Alzheimer’s risk change how people decide between immediate and delayed rewards and risky options, with the goal of helping older adults stay financially and healthwise safer.
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Whole Person Pain Algorithm to personalize chronic pain care
A new, evidence-based model helps explain why chronic low back pain affects people differently and could guide personalized diagnosis and treatment.
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Dysregulation of lipid metabolism and signaling in LAM (a rare lung disease in young women)
This grant looks at how fat-related molecules and their signals may drive lung disease in women with LAM, with the goal of finding better ways to treat it.
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Molecular Guided T Cells to help neurodegeneration
A new T cell therapy approach is explored to slow progression in dementia with Lewy bodies and Parkinson’s disease for patients affected by these disorders.
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Improving after-hours pediatric care with a telemedicine and medicine-delivery tool using smart technology
A pediatric telemedicine and medication delivery service is being improved with smart tools to help kids get quick after-hours care, especially when a clinic is closed.
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Bringing red-light therapy into everyday dental care
A study to see if red-light therapy can safely help people heal after dental procedures when used with standard fillings and restorations.
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Cholinergic signals and thinking in Lewy body dementia
This grant explores how acetylcholine signaling in a specific brain region affects thinking and memory in Lewy body dementia and related conditions.
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Optimizing dolutegravir-based ART for children and teens with HIV
This grant tests better dosing and regimens of dolutegravir for kids and adolescents with HIV to improve health outcomes.
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AI-powered CKD risk predictor and care tool
A cloud-based AI tool will combine medical records, images, and pathology data to predict a patient’s 5-year CKD risk and highlight modifiable factors to guide care.
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ReMARk: Targeting rural HPV cancer prevention gaps
A rural-focused initiative will map cancer risk in small neighborhoods to find where HPV prevention efforts like vaccines and screening are most needed.
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APOE4 and inflammation effects on breathing control health outcomes
This project studies how a common genetic factor (APOE4) and inflammation affect a key form of breathing plasticity that could influence breathing in people with spinal cord injury or ALS.
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Hybrid biomaterial system to boost immunotherapy for rheumatoid arthritis
A new, patient-facing immunotherapy approach uses specialized particles to retrain the immune system to calm RA in adults.
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Administrative supplement to advance mapping of nervous system in knee and jaw osteoarthritis
A supplemental NIH grant helps UF-Pitt expand advanced 3-D mapping of how nerves relate to chronic knee and jaw osteoarthritis using rat models and human samples.
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3D human pancreatic tissue model to study T1D immune interactions
A small, 3D printed tissue platform made from human cells is being developed to better understand how immune cells interact with insulin-producing cells in type 1 diabetes and to test new treatments.
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Phone-based support to help people quit smoking in Lebanon and US clinics
This grant tests scalable, real-world ways to implement proven smoking-cessation help in primary care, especially in Lebanon, to reach more adults who smoke.
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Biobehavioral signatures of repetitive head impacts and aging-related dementia
Aging adults with a history of repetitive head impacts are being studied to understand how these exposures relate to brain changes and Alzheimer’s-related markers.
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Molecular mechanisms of how cell attachments work in tissues
A researcher at the University of Florida is studying how cells stick to each other and to their surroundings to keep tissues healthy, which could help treat diseases that disrupt these connections.
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Gateway Program for Vector-Borne Diseases in the Southeast
A national network led by the University of Florida is renewing funding to strengthen surveillance, training, and coordinated responses to vector-borne diseases across the Southeast and Puerto Rico.
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Predicting and Preventing Chronic Aspiration After Traumatic Cervical Spinal Cord Injury
This project looks at swallowing problems and chronic aspiration in adults with traumatic neck spine injuries to find patterns that could prevent serious lung complications.
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Advanced malaria surveillance and diagnostics to curb asymptomatic and non-falciparum malaria
A large, multi-site project at the University of Florida aims to improve how we find and treat malaria, especially when people don’t feel sick or have non-falciparum infections.
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AI-powered smart traps to monitor malaria-carrying mosquitoes in Africa
A large NIH grant funds the development of AI-driven traps and fast identification tools to help track and control malaria-carrying mosquitoes in sub-Saharan Africa, with potential benefits for children and communities at risk.
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Genomic mapping of nonfalciparum malaria to guide control in Africa
A large, multi-institution project aims to map the spread and transmission of nonfalciparum malaria (Po, Pv, Pm) to better understand where these infections come from and how mosquitoes pass them on.
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Data Management Core supports secure data and statistics for a global infectious disease program
A data management and statistics center helps researchers securely collect, store, and analyze data from a large, international study on emerging infections.
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Emergents International Centers of Excellence for Malaria Research
A multinational malaria research program at the University of Florida aims to coordinate and advance malaria surveillance and research across multiple centers.
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Pathogenesis and diagnosis of area C malaria in diverse age groups
A nationwide program aims to improve malaria detection and understanding of transmission, including asymptomatic cases, to help end malaria in diverse populations.
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Bionomics, Ecology, & Control of Anopheles stephensi using AI-powered traps
A multi-project effort to understand malaria-carrying mosquitoes and test new AI-enabled traps and rapid testing tools to reduce malaria risk in Africa.
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Genomic Mapping of Non-Falciparum Malaria to Inform Control
A multifaceted research effort to map non-falciparum malaria parasites and how they spread, with the aim of informing better prevention in Africa.
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Data Management Core for a global infectious disease research program
A data management and biostatistics core supports a large international research program by organizing data securely and enabling high-quality analyses.
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Emergents International Centers of Excellence for Malaria Research
A multinational malaria research effort will coordinate advanced genomics, vector biology, and data science to improve malaria surveillance and understanding across Africa.
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West-Central Africa ICEMR: Advancing Malaria Understanding and Control
A large international effort will study malaria in West-Central Africa to better understand how malaria spreads and how to control it, with a focus on diverse mosquito species and parasite types.
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West-Central Africa ICEMR: malaria epidemiology through genomics and systems biology
A global malaria project in West-Central Africa will study how mosquitoes and parasites spread malaria, using genomics and systems biology to improve control efforts.
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Probiotic-derived SH3b domains guiding how beneficial bacteria influence our body
This project explores a protein piece from a probiotic bacterium and how it can trigger immune signals and potentially benefit the gut and beyond.
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Reprogramming immune cells to restore ovarian function and fight ovarian tumors
This work aims to turn a type of immune cell into helpers that could restore ovarian function for women with autoimmune ovarian failure and be adjusted to boost immune attack on ovarian tumors.
Quick answers
How many clinical trials run by University of Florida are recruiting right now?
153, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (151 trials), Haiti (1 trial), Lebanon (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 19, Phase 4: 10, Phase 1/2: 6, Phase 1: 5. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.