Clinical trial Recruiting at 1 site Observational Ages 40 to 80

Pre-surgery exercise program to improve internal rotation after reverse shoulder replacement

Official title: Does Undergoing a Prehabilitation Protocol Aimed at Optimizing Scapulothoracic Mobility and Strengthening Improve Internal Rotation After Reverse Shoulder Arthroplasty? A Randomized Controlled Trial

Run by University of Florida · NCT07145957 · Data updated 2026-11-12

A 6-week pre-surgery exercise program that tries to help people getting a reverse shoulder replacement improve internal rotation by strengthening and mobilizing the shoulder girdle.

Quick facts

Study typeObservational
Ages40 Years to 80 Years
SexAll
Enrollment64 (estimated)
SponsorUniversity of Florida
Academic / other
Locations1 site (Gainesville, Florida)
StatusRecruiting
StartedNovember 6, 2025
Main results expectedSeptember 1, 2028
Study endsSeptember 1, 2028
Registry record updatedJanuary 14, 2026
Trial IDNCT07145957 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 40–80 undergoing primary reverse shoulder arthroplasty for glenohumeral osteoarthritis or rotator cuff arthropathy who can attend monthly therapy, perform home exercises for six weeks before surgery, and commit to two years of follow-up.

Probably not a fit

Patients with septic shoulder, fracture or tumor pathology, revision procedures, planned intraoperative tendon transfers, significant hand/wrist/elbow limitations, or those unable to attend prehab sessions or long-term follow-up are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 40–80 scheduled for primary reverse total shoulder arthroplasty for glenohumeral osteoarthritis or rotator cuff arthropathy are randomized to either a targeted 6-week prehabilitation program or usual care. The prehabilitation emphasizes scapulothoracic mobility and internal rotation strengthening delivered with monthly therapy visits plus home exercises. Outcomes include internal rotation range of motion, strength, patient-reported function for activities of daily living that require internal rotation, and at least two years of postoperative monitoring. The trial excludes revision cases, fractures, tumor pathology, planned tendon transfers, and patients unable to complete the prehab or follow-up requirements.

Why it matters

Potential benefit: If successful, patients could have better internal rotation and improved ability to perform daily tasks after reverse shoulder replacement.

How similar studies have gone: Most prior efforts to improve internal rotation after reverse arthroplasty focused on surgical or implant changes, and prehabilitation targeting scapulothoracic mechanics is relatively novel with limited direct evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: • Patients aged 40-80

* Undergoing primary RSA for glenohumeral osteoarthritis or rotator cuff arthropathy
* Must be able to read and speak English
* Willing and able to attend a monthly therapy session and perform exercises at home for a minimum of 6 weeks before surgery
* Willing and able to participate in postoperative monitoring for a minimum of 2 years

Exclusion Criteria:

* Patients under the age of 40 and over the age of 80.
* Diagnosis of septic shoulder, fracture, or fracture sequelae, or tumor pathology of the ipsilateral shoulder
* Pre-existing hand, wrist, or elbow pathology that limits elbow flexion or extension, or forearm pronation or supination
* Planned to undergo synchronous procedure of the involved extremity (e.g., synchronous RSA and carpal tunnel release)
* Tendon transfer (e.g., Latissimus dorsi transfer) performed intraoperatively
* Patients without access to phone or email communication for at least 2 years after treatment
* Revision shoulder arthroplasty

Where it's running

  • University of Florida Department of Orthopaedics and Rehabilitation
    Gainesville, Florida, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.