Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Examining how different terrains affect foot muscle strength in healthy people and those with plantar fasciitis

Official title: A Randomized Control Trial Studying the Effects of Terrain Variation on Intrinsic Foot Musculature in Healthy Individuals and Individuals With Plantar Fasciitis:

Run by University of Florida · NCT05075005 · Data updated 2026-11-12

This study is testing how walking on different types of surfaces affects foot muscle strength in healthy people and those with plantar fasciitis.

More Plantar Fasciitis trials

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment60 (estimated)
SponsorUniversity of Florida
Academic / other
Locations1 site (Gainesville, Florida)
StatusRecruiting
StartedSeptember 15, 2024
Main results expectedJanuary 20, 2027
Study endsJanuary 20, 2027
Registry record updatedSeptember 10, 2026
Trial IDNCT05075005 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals over 18 years old with chronic heel pain due to plantar fasciitis lasting more than 60 days.

Probably not a fit

Patients with recent foot or lower leg surgeries, certain neurological conditions, or those who have not experienced chronic heel pain may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of terrain variation on the strength of intrinsic foot muscles in both healthy individuals and those suffering from plantar fasciitis. It aims to understand how modern footwear and a lack of varied terrain may contribute to foot pathologies by examining the relationship between terrain, muscle function, and structural changes in the foot. Participants will be divided into treatment and control cohorts to assess these effects over time.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for plantar fasciitis and enhance overall foot health.

How similar studies have gone: Previous observational studies have indicated that varying terrain may reduce the prevalence of foot pathologies, suggesting that this approach could be promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria for Group A:

* Patients presenting to the University of Florida Orthopaedics and Sports Medicine Institute with pain on the plantar medial or central heel for greater than 60 days with the following features
* Pain upon palpation, or insidious pain onset
* Pain accentuated after long periods of weight bearing activities or after periods of rest
* A reduction in pain following light activities (McPoil et al., 2008)
* Failure to respond to treatment modalities for 6 months, including plantar fascia and muscle stretching, nonsteroidal anti-inflammatory medication, supportive insoles, and night splints
* Age \>18 years

Inclusion Criteria for Group B:

* Healthy individuals in the general population of Gainesville and surrounding areas
* Age \>18

Exclusion Criteria for Group A:

* History of lower leg or foot surgery, hindfoot trauma or fracture of the affected limb within the previous year.
* Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease, Achilles tendinopathy, metatarsalgia, tarsal tunnel syndrome or heel pad syndrome
* Body Mass Index (BMI) \> 35
* Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter
* Third trimester pregnancy

Exclusion Criteria for Group B:

* Any foot or lower limb pathology resulting in discomfort or gait limitation
* Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease
* BMI \>35
* Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter
* Third trimester pregnancy

Where it's running

  • UF Health Orthopaedics and Sports Medicine Institute
    Gainesville, Florida, United States
    Recruiting

Study contacts

  • Principal investigator: Antony Merendino, DPM — University of Florida
  • Study coordinator: Antony Merendino, DPM
  • Email: merena@ortho.ufl.edu
  • Phone: 352-273-7198

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.