Examining how different terrains affect foot muscle strength in healthy people and those with plantar fasciitis
Official title: A Randomized Control Trial Studying the Effects of Terrain Variation on Intrinsic Foot Musculature in Healthy Individuals and Individuals With Plantar Fasciitis:
Run by University of Florida · NCT05075005 · Data updated 2026-11-12
This study is testing how walking on different types of surfaces affects foot muscle strength in healthy people and those with plantar fasciitis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Florida Academic / other |
| Locations | 1 site (Gainesville, Florida) |
| Status | Recruiting |
| Started | September 15, 2024 |
| Main results expected | January 20, 2027 |
| Study ends | January 20, 2027 |
| Registry record updated | September 10, 2026 |
| Trial ID | NCT05075005 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals over 18 years old with chronic heel pain due to plantar fasciitis lasting more than 60 days.
✕Probably not a fit
Patients with recent foot or lower leg surgeries, certain neurological conditions, or those who have not experienced chronic heel pain may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of terrain variation on the strength of intrinsic foot muscles in both healthy individuals and those suffering from plantar fasciitis. It aims to understand how modern footwear and a lack of varied terrain may contribute to foot pathologies by examining the relationship between terrain, muscle function, and structural changes in the foot. Participants will be divided into treatment and control cohorts to assess these effects over time.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for plantar fasciitis and enhance overall foot health.
How similar studies have gone: Previous observational studies have indicated that varying terrain may reduce the prevalence of foot pathologies, suggesting that this approach could be promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria for Group A: * Patients presenting to the University of Florida Orthopaedics and Sports Medicine Institute with pain on the plantar medial or central heel for greater than 60 days with the following features * Pain upon palpation, or insidious pain onset * Pain accentuated after long periods of weight bearing activities or after periods of rest * A reduction in pain following light activities (McPoil et al., 2008) * Failure to respond to treatment modalities for 6 months, including plantar fascia and muscle stretching, nonsteroidal anti-inflammatory medication, supportive insoles, and night splints * Age \>18 years Inclusion Criteria for Group B: * Healthy individuals in the general population of Gainesville and surrounding areas * Age \>18 Exclusion Criteria for Group A: * History of lower leg or foot surgery, hindfoot trauma or fracture of the affected limb within the previous year. * Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease, Achilles tendinopathy, metatarsalgia, tarsal tunnel syndrome or heel pad syndrome * Body Mass Index (BMI) \> 35 * Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter * Third trimester pregnancy Exclusion Criteria for Group B: * Any foot or lower limb pathology resulting in discomfort or gait limitation * Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease * BMI \>35 * Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter * Third trimester pregnancy
Where it's running
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UF Health Orthopaedics and Sports Medicine Institute
Gainesville, Florida, United States Recruiting
Study contacts
- Principal investigator: Antony Merendino, DPM — University of Florida
- Study coordinator: Antony Merendino, DPM
- Email: merena@ortho.ufl.edu
- Phone: 352-273-7198
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Extracorporeal Shock Wave Therapy With or Without Kinesio Taping for Plantar Fasciitis
This study tests whether adding kinesio taping to shock wave therapy helps reduce pain and improve foot function in people with plantar fasciitis.
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Transverse Friction Massage vs Instrument-Assisted Soft-Tissue Mobilization for Plantar Fasciitis
This study tests whether transverse friction massage or instrument-assisted soft-tissue mobilization helps people with plantar fasciitis feel better.
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Ice packs vs cold baths with standard exercise for heel pain from plantar fasciitis
This trial tests whether ice packs or cold baths, when added to a standard exercise plan, better reduce pain for adults with plantar fasciitis.
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Do Myofascial Release or Instrument-Assisted Soft Tissue Mobilization Help Pregnant Women with Plantar Fasciitis
This study tests whether two manual therapy techniques, MFR and IASTM, can reduce heel pain and improve foot function in pregnant women with plantar fasciitis.
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Relationship between central sensitization and clinical features in plantar fasciitis
This study tests how brain-sensitivity, pain intensity, and psychological factors relate to ultrasound findings and how patients function with plantar fasciitis.
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Barefoot Walking vs Standardised Conservative Care for Plantar Fasciopathy
This trial tests whether a barefoot walking program can reduce heel pain and improve foot function in adults with plantar fasciopathy compared with a standard stretching and strengthening program.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.