Living Independently with Functional Training
Living Independence Through Functional Training (LIFT): Feasibility of Hybrid Task-Oriented Resistance Exercise Following Home Health Discharge
This six-week hybrid home- and clinic-based task-oriented resistance exercise program tests whether recently discharged older adults with mobility limitations and mild cognitive impairment can improve daily function and mobility.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 65 Years to 90 Years |
| Sex | All |
| Sponsor | University of Florida Academic / other |
| Locations | 2 sites (Gainesville, Florida and 1 other locations) |
| Trial ID | NCT07125378 on ClinicalTrials.gov |
What this trial studies
This Phase 1/2 interventional program delivers a six-week hybrid task-oriented resistance exercise regimen to older adults recently discharged from home health care. Participants perform task-specific strength exercises at home with remote support, occasional in-person sessions, and continuous activity monitoring via a wearable tracker. Eligibility targets community-dwelling adults aged 65–90 with mobility limitations and cognitive decline (Mini MoCA <12), who have a nearby care partner and live within the study area. The trial measures feasibility, safety, adherence, and changes in mobility and activities of daily living.
Who should consider this trial
Good fit: Community-dwelling adults aged 65–90 recently discharged from home health care who use a mobility aid or have slowed/unsteady gait, show cognitive decline on Mini MoCA, have a nearby care partner, and live within the study area with wireless connectivity.
Not a fit: Patients who cannot stand or walk even with an aid, have severe vision/hearing or communication impairments, reside in or plan to move to assisted living/long-term care, or plan to receive skilled rehabilitation are unlikely to benefit.
Why it matters
Potential benefit: If successful, participants could gain better mobility and greater independence in daily activities, potentially reducing future care needs.
How similar studies have performed: Prior home-based and task-oriented resistance programs have shown improvements in mobility and daily function in older adults, though evidence is more limited for people with concurrent cognitive impairment.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * between the ages of 65 and 90 years * community-dwelling * live within a 50-mile radius of the study site with wireless connectivity in the area * mobility limitations as indicated by self-reported of using a mobility aid or having unsteady gait or walking slower than before * cognitive decline as indicated by a score \< 12 on Mini MoCA Version 2.1 * a care partner or adult family member living in the home or nearby * willing to wear an activity tracker during the study period Exclusion Criteria: * plan to receive skilled rehabilitation services * plan to move away outside the study area in two months * reside in an assisted living or long-term care facility or plan to relocate to such a facility in the next three months * severe vision or hearing loss that impedes activity performance or communication * unable to stand or walk even with a mobility aid * unable to follow a one-step command or carry on a conversation over the phone * unable to commit to the six-week exercise program * contradictions to resistance exercise, such as the end-stage heart failure * a terminal disease or on hospice care * a neurological condition affecting motor skills * not able to provide consent.
Where this trial is running
Gainesville, Florida and 1 other locations
- College of Public Health and Health Professions, University of Florida — Gainesville, Florida, United States (Recruiting)
- University of Florida — Gainesville, Florida, United States (Not_yet_recruiting)
Study contacts
- Principal investigator: Chiung-ju Liu Associate Professor, phD — University of Florida
- Study coordinator: Chiung-ju Liu Associate Professor, PhD
- Email: c.liu1@phhp.ufl.edu
- Phone: 352-273-6496
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.