Clinical trial Recruiting at 1 site Interventional Ages 21 and up

Comparing mobile health approaches for quitting smoking in underserved patients

Official title: Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care

Run by University of Florida · NCT05415761 · Data updated 2026-11-12

This study is testing three different ways to help underserved adults quit smoking to see which one works best for them.

Quick facts

Study typeInterventional
Ages21 Years and up
SexAll
Enrollment1332 (estimated)
SponsorUniversity of Florida
Academic / other
Locations1 site (Gainesville, Florida)
StatusRecruiting
StartedMay 15, 2023
Main results expectedJune 30, 2027
Study endsDecember 31, 2027
Registry record updatedJune 12, 2026
Trial IDNCT05415761 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 21 and older who smoke and receive care at participating primary care clinics.

Probably not a fit

Patients with unstable medical or psychiatric illnesses may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of three smoking cessation therapies among underserved adult patients in primary care settings in North Central Florida. Participants will be randomly assigned to one of three interventions: the iCanQuit mobile health application, the iCanQuit application combined with Motiv8, or the Florida quit line. The study will assess smoking cessation rates through breath tests at 2, 6, and 12 months, while also measuring quality of life, self-confidence in quitting, and treatment satisfaction. The research aims to understand how these interventions impact motivation and commitment to quitting smoking across different demographics.

Why it matters

Potential benefit: If successful, this study could provide effective smoking cessation tools tailored for underserved populations, improving their health outcomes.

How similar studies have gone: Other studies have shown promise in using mobile health interventions for smoking cessation, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥21 years old
* Referred by the provider via Ask-Advise-Connect
* Receiving care at one of the participating clinics
* Daily access to their own smart phone (the study team will provide assistance to patients without a phone to obtain one through aid programs for low-income patients)
* No household members already enrolled

Exclusion Criteria:

* Unstable medical or psychiatric illness

Where it's running

  • University of Florida
    Gainesville, Florida, United States
    Recruiting

Study contacts

  • Principal investigator: Jesse Dallery, PhD — University of Florida
  • Study coordinator: Jesse Dallery, PhD
  • Email: dallery@ufl.edu
  • Phone: 352-273-2182

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Automating Tobacco Cessation in Primary Care

    This project tests a workflow in primary care to identify smokers and help them access nicotine replacement therapy (NRT) during routine visits.

    Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07735286

  • Text2Quit-Kenya: a mobile message program to help ED patients quit tobacco

    Researchers will test a text message-based smoking-cessation program with Kenyan emergency department patients to see if it helps people quit and learn what works in this setting.

    Recruiting Yale University · Nairobi · NCT07734727

  • Extended tobacco support for people experiencing homelessness

    This program tests whether extending tobacco treatment to 6 months with pharmacist counseling, monthly nicotine replacement deliveries, and phone wellness coaching helps adults experiencing homelessness quit smoking compared with a 3-month package.

    Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07148232

  • Trauma-informed smoking cessation support during pregnancy

    This project will test a trauma-informed smoking cessation program that combines the 4Rs with the 5As to help pregnant women who smoke and have histories of trauma.

    Recruiting University of California, San Francisco · San Francisco, California · NCT07129590

  • Treatment for quitting cigarettes and reducing cannabis use

    This study tests if a medication called varenicline can help adults who smoke cigarettes and use cannabis quit smoking and cut down on cannabis use, with support from counseling and online resources.

    Recruiting Phase 3 Medical University of South Carolina · Charleston, South Carolina · NCT06883162

  • Improving tobacco cessation support for patients in poverty in Utah

    This study is testing new ways to help people living in poverty in Utah quit smoking by using support tools and strategies in their healthcare clinics.

    Recruiting University of Utah · Salt Lake City, Utah · NCT06881069

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.