Alcohol sensitivity in healthy adults aged 65–80 who drink

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a proof-of-concept study enrolling healthy adults aged 65 to 80 who regularly drink. Participants attend two lab sessions in which they complete questionnaires and cognitive and brain activity measures, and receive beverages that may or may not contain a moderate dose of alcohol. If alcohol is given, the amount will approximate what is consumed in 1–2 standard drinks. The study aims to describe variability in alcohol response among older adults and explore links between alcohol sensitivity and cognitive test results. About 75 individuals are planned to participate, conducted at the University of Florida with collaboration from NIAAA.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Alcohol Drinkers who consume alcohol on a regular basis
* No history of significant substance misuse
* at least 12 years of education or GED equivalence Exclusion Criteria
* current Cigarette smoker
* Type 1 Diabetes or uncontrolled Type 2 Diabetes
* Epilepsy
* Neurodegenerative disorder
* Significant psychiatric disorder such as a psychotic disorder, bipolar disorder, current major depression or PTSD

Where it's running

• University of Florida
  Gainesville, Florida, United States Recruiting

Study contacts

• Principal investigator: Sara Jo Nixon, PhD — University of Florida
• Study coordinator: Sara Jo Nixon, PhD
• Email: sjnixon@ufl.edu
• Phone: 352-294-4920

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How age affects germinal center responses after flu and rabies vaccines

  Researchers will test how the immune system responds to flu and rabies vaccines in younger adults (18–40) and older adults (65+).

  Recruiting Phase 4 Washington University School of Medicine · St Louis, Missouri · NCT07914673

• Magnetic field maps with NV sensors for non-invasive heart measurements

  This study tests whether diamond-based NV magnetometers can non-invasively detect and map the heart's magnetic field in healthy adults.

  Recruiting Robert Bosch GmbH · Renningen · NCT07908173

• Methylation analyses using home-based self-sampling in women with and without gynecological disease

  This study tests whether self-collected urine and vaginal samples can reveal DNA methylation markers that distinguish people with gynecological (pre-)cancers from cancer-free controls.

  Recruiting Universiteit Antwerpen · Edegem, Antwerp · NCT07902388

• Omega-3 status in healthy adults: comparing different fish-oil and algae-oil products

  This study tests whether various fish-oil and algae-oil products can raise the Omega-3 Index in healthy adults who don’t eat much fatty fish.

  Recruiting Nordic Naturals · London, Ontario · NCT07900425

• A safe, carefully dosed test of TBD11 in healthy adults

  This phase 1 study tests TBD11 in healthy adults to see if it is safe and tolerable and to understand how it behaves in the body, including how it interacts with other medicines.

  Recruiting Phase 1 Gates Medical Research Institute · Bloemfontein · NCT07883226

• Fosmanogepix in healthy adults: how it may interact with other drugs and heart rhythm

  This study tests whether fosmanogepix (and its active form manogepix) changes how other medicines work in healthy adults.

  Recruiting Phase 1 Basilea Pharmaceutica · Groningen, Netherlands · NCT07881224

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.