Study on physical and cognitive aging in older Hispanic adults
PASOS: Physical and Cognitive Aging Study in Older Adults
University of Florida · NCT06726616
This study is trying to see how physical activity and thinking skills change over time in older Hispanic adults to understand aging better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 55 Years to 85 Years |
| Sex | All |
| Sponsor | University of Florida (other) |
| Locations | 1 site (Jacksonville, Florida) |
| Trial ID | NCT06726616 on ClinicalTrials.gov |
What this trial studies
This observational study aims to recruit and retain older adults, specifically focusing on Hispanic Americans, to assess the feasibility of enrolling them into a longitudinal aging cohort. The study will evaluate differences in physical activity, physical function, and cognitive performance over time, utilizing assessments such as the Montreal Cognitive Assessment (MoCA) to determine eligibility. Participants will undergo initial evaluations and follow-up assessments to generate preliminary data on the associations between physical and cognitive aging trajectories.
Who should consider this trial
Good fit: Ideal candidates for this study are Hispanic and non-Hispanic adults aged 55-85 who are community-dwelling and have no evidence of dementia or mild cognitive impairment.
Not a fit: Patients with severe disabilities, significant sensory loss, or major brain abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify factors that mitigate cognitive decline in older Hispanic adults, potentially leading to improved health outcomes.
How similar studies have performed: Other studies focusing on aging trajectories in diverse populations have shown promise, indicating that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: • Hispanic and non-Hispanic adults age 55-85 years, at least 8th grade education, community dwelling. Additional Inclusion for Hispanic Americans * Self-identify as Hispanic American * Report Spanish as primary language • No evidence of dementia or mild cognitive impairment based on cognitive screening \[i.e., Montreal Cognitive Assessment (MoCA) administered during Visit 1; ≥26 among non-Hispanic White, ≥25 among Hispanics, ≥24 among non-Hispanic Blacks (Milani et al., 2018)\] Exclusion Criteria: * Inability to provide informed consent * Artificial joint or severe disability that would make it impossible or contraindicated performing the isokinetic test * Sensory loss (vision, hearing) or motor deficits that would preclude participation in the experimental tasks or neuropsychological assessment * Previous major strokes or other known significant brain abnormalities or diseases affecting the brain and/or cognition (e.g., Parkinson disease, multiple sclerosis, seizure disorder, brain surgery, moderate TBI, REM Behavior Sleep Disorder, untreated sleep apnea, etc.) * Unstable and uncontrolled medical conditions (metastatic cancer, HIV, moderate-severe kidney disease, uncontrolled diabetes, uncontrolled hypertension, severe cardiac disease, etc.). No current cancer diagnosis. * Current or past history of major psychiatric disturbance including schizophrenia, or active psychosis, bipolar disorder, current major depressive episode, current alcohol or substance abuse or history thereof within the past six months * Use of antipsychotics, sedatives, or other medications with significant anticholinergic properties (due to potential influence on memory) * Use of prescribed 'memory enhancing' medications, such as Aricept or Namenda * Previous participation in a cognitive or physical activity training study within the last 6 months or current involvement in another study involving cognitive, physical or other intervention at the time of enrollment
Where this trial is running
Jacksonville, Florida
- University of Florida, College of Medicine-Jacksonville — Jacksonville, Florida, United States (RECRUITING)
Study contacts
- Study coordinator: Stacey Alvarez-Alvarado, PhD, MS
- Email: salvarezalvarado@ufl.edu
- Phone: 904-244-9937
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Older Adults, Hispanic Americans, Cognitive Aging, Aging, Healthy, Exercise