Genomic mapping of nonfalciparum malaria to guide control in Africa
Official title: Emergents International Centers of Excellence for Malaria Research
Funded at University of Florida · NIH-11507593 · Data updated 2026-11-12
A large, multi-institution project aims to map the spread and transmission of nonfalciparum malaria (Po, Pv, Pm) to better understand where these infections come from and how mosquitoes pass them on.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | April 22, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $36,054 |
| NIH project number | 3U19AI181594-03S2 |
| Project ID | NIH-11507593 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals in malaria-endemic regions, particularly in Africa, who may be harboring nonfalciparum infections and could benefit from improved diagnosis and vector-control strategies.
✕Less likely to help
Individuals without malaria exposure or those in settings without access to targeted diagnostic tools and vector-control interventions may see limited direct benefit.
What this research studies
This program project will use genomic epidemiology to identify where nonfalciparum malaria infections live, how easily they move to mosquitoes, and how insecticide resistance in vectors affects transmission. It focuses on Po, Pv, and Pm, which are harder to diagnose with standard field tests, and will apply sensitive detection methods to reveal the true disease burden. Researchers will study mosquito behavior and the impact of insecticides on transmission to develop better prevention strategies. The effort involves collaboration across multiple sites, with data guiding targeted interventions in affected regions.
Why it matters
Potential benefit: Better understanding of nonfalciparum malaria could lead to more accurate diagnosis, tailored control measures, and reduced transmission in areas with high disease burden.
How similar studies have gone: Previous work has improved understanding of Plasmodium falciparum and vivax; this project extends genomic approaches to rarer nonfalciparum infections, which is promising but underexplored.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Dinglasan, Rhoel David Ramos — University of Florida
- Study coordinator: Dinglasan, Rhoel David Ramos
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.