Advanced malaria surveillance and diagnostics to curb asymptomatic and non-falciparum malaria
Official title: Area C Pathogenesis and Diagnosis
Funded at University of Florida · NIH-11507595 · Data updated 2026-11-12
A large, multi-site project at the University of Florida aims to improve how we find and treat malaria, especially when people don’t feel sick or have non-falciparum infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | April 22, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $52,720 |
| NIH project number | 3U19AI181594-03S2 |
| Project ID | NIH-11507595 on NIH RePORTER |
Who could benefit from this research
✓Could help
People of all ages in malaria-endemic settings, including children and adults who may carry asymptomatic infections or non-falciparum malaria.
✕Less likely to help
Individuals without exposure to malaria or those who do not participate in surveillance or sampling activities may not directly benefit.
What this research studies
This project uses new diagnostic and translational biology platforms to detect and understand asymptomatic malaria and infections from species other than falciparum. It combines clinical data, entomology, and multiomics approaches to identify parasite reservoirs and inform treatment and policy decisions. The work seeks to translate lab findings into practical tools and strategies that can help reduce malaria transmission and move toward elimination goals. It involves collaboration across clinical sites, field surveillance, and advanced molecular methods to capture a more complete picture of malaria dynamics.
Why it matters
Potential benefit: If successful, patients and communities could benefit from more accurate diagnostics, better-targeted treatments, and policies that reduce malaria transmission.
How similar studies have gone: Previous malaria surveillance efforts have shown promise when integrating molecular diagnostics with field data, but translating multiomics findings into practice is still evolving.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Dinglasan, Rhoel David Ramos — University of Florida
- Study coordinator: Dinglasan, Rhoel David Ramos
Related research
Other NIH-funded projects on the same topics.
-
Mitochondrial pores and muscle loss in cancer cachexia
A small US-based study will explore how changes in mitochondria contribute to muscle wasting in people with cancer cachexia and how this may be slowed.
-
Photobiomodulation for jaw pain from TMD
A clinician-scientist at the University of Florida is testing a light-based therapy to help adults with temporomandibular disorder pain feel better and jaw function improve.
-
How the brain controls swallowing and airway protection
A research team at the University of Florida is studying how brain networks control swallowing to reduce risk of choking and lung infections in people with neuromuscular diseases.
-
Donor-driven 3D organoid platform to study pancreatic cancer drug response
A pilot project to create patient-derived, 3D organoid models of pancreatic cancer to measure how tumors from different people respond to chemotherapy.
-
RAAS inhibitors and pancreatic cancer risk in diverse adults
A Florida-based study will look at whether commonly used blood pressure medicines (RAAS inhibitors) are linked to new cases of pancreatic cancer, especially among Black and Hispanic adults.
-
Pilot project exploring new cancer drugs for pancreatic cancer in African American patients
A small, early-stage project tests new drug-derived compounds to treat pancreatic cancer, focusing on African American patients who are disproportionately affected.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.