Cognitively engaging walking exercise and brain stimulation for older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of combining cognitively engaging walking exercises with non-invasive electrical brain stimulation on cognitive and mobility functions in older adults. Participants will engage in complex walking tasks while receiving either active or sham transcranial direct current stimulation (tDCS) over a period of six weeks. The primary outcomes will assess improvements in executive function and walking abilities through standardized assessments. The trial aims to enroll up to 120 older adults with mild to moderate cognitive decline, conducted at two sites in Florida.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 65+
* Objective executive function decline, based on standardized cognitive assessments.
* Subjective cognitive decline, based on the question: "During the past 12 months, have you experienced confusion or memory loss that is happening more often or getting worse?"
* Ability to walking independently for 6 minutes (use of cane permitted)

Exclusion Criteria:

* Major cognitive disorder that interferes with independence
* Percentile score less than 10th percentile on standardized cognitive assessments
* Medications that are thought to influence tDCS neuroplasticity.
* Contraindications to tDCS or MRI.

Where it's running

• University of Florida
  Gainesville, Florida, United States Recruiting
• Brooks Rehabilitation
  Jacksonville, Florida, United States Recruiting

Study contacts

• Principal investigator: David J Clark, ScD — University of Florida
• Study coordinator: David J Clark, ScD
• Email: davidclark@ufl.edu
• Phone: 352-376-1611

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.