Clinical trial Recruiting at 1 site Interventional Ages 18 to 24

Momentary Coping Prompts and Hair Steroids in College Students

Official title: REACT Biomarker and Extended-Measures Study: Hair Steroids, Psychosocial Moderators, and Momentary Reactive Behavior in College Students

Run by University of Florida · NCT07782398 · Data updated 2026-11-12

This trial tests whether sending brief coping prompts at moments of emotional volatility helps college students respond to emotions, while collecting hair samples to see if long-term stress hormones relate to those responses.

More Aggression trials

Quick facts

Study typeInterventional
Ages18 Years to 24 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Florida
Academic / other
Locations1 site (Gainesville, Florida)
StatusRecruiting
StartedSeptember 21, 2026
Main results expectedMay 2027
Study endsDecember 2027
Registry record updatedNovember 5, 2026
Trial IDNCT07782398 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are UF students aged 18–24 who own a smartphone, are willing to wear a wrist device, and can complete frequent check-ins for about five weeks (with an optional hair sample sub-study).

Probably not a fit

Participants who do not experience high moment-to-moment emotional variability or do not engage with prompts may see little to no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

REACT is a five-week micro-randomized trial with college students at UF. Participants wear a wrist device and answer multiple smartphone check-ins daily to capture momentary mood changes. In weeks two to five, the app may deliver a coping message at up to six random decision points per day when emotional variability is high, to see if the prompts influence immediate behavior. Randomization assigns prompts with a 50% probability, with safeguards like cooldowns and data quality checks. An optional hair sample subgroup examines cortisol and testosterone to explore links between chronic stress physiology and in-the-moment responses. The study uses personalized baselines and causal analysis to estimate the effect of prompts on proximal outcomes.

Why it matters

Potential benefit: If successful, prompts could inform personalized, just-in-time strategies to help students manage emotions and related behaviors.

How similar studies have gone: Similar just-in-time and micro-randomized approaches have shown potential in momentary interventions for emotion-related behaviors, though this exact setup is novel in its combination with hair biomarkers.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Currently enrolled University of Florida student
* Age 18 to 24 years
* Owns a smartphone used daily
* Willing to wear a wrist-worn device and complete brief check-ins several times daily for approximately five weeks
* For the optional hair biomarker sub-study only: at least approximately 1 cm of hair at the posterior vertex, no scalp wound, rash, or dermatologic treatment at the collection site, and natural hair growth accessible at the collection site

Exclusion Criteria:

* Varsity student-athlete governed by the university athletic association
* Unable to complete study procedures in English

Where it's running

  • University of Florida
    Gainesville, Florida, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.