NIH-funded research NIH-funded research

Pathogenesis and diagnosis of area C malaria in diverse age groups

Official title: Area C Pathogenesis and Diagnosis

Funded at University of Florida · NIH-11507440 · Data updated 2026-11-12

A nationwide program aims to improve malaria detection and understanding of transmission, including asymptomatic cases, to help end malaria in diverse populations.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida
NIH-funded
Lab location1 site (Gainesville, United States)
Project startApril 22, 2024
Project endMarch 31, 2029
Funding year2026
Award (this year)$33,546
NIH project number3U19AI181594-03S1
Project IDNIH-11507440 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals across ages 0-11 and 21+ living in malaria-endemic areas who may participate in diagnostic testing, blood sampling, or surveillance activities.

Less likely to help

Participants not contributing to malaria surveillance or lacking access to study sites may have no direct benefit.

What this research studies

This grant supports a large, collaborative effort at the University of Florida to develop and apply advanced diagnostic and multiomics approaches to malaria. The project focuses on identifying asymptomatic infections and non-falciparum malaria, and on translating findings into better surveillance and control strategies. Researchers will integrate clinical data, entomology, and molecular methods to map transmission and inform treatment and policy decisions. The work is designed to reveal how subclinical infections contribute to ongoing transmission and how new diagnostic platforms can reduce malaria burden.

Why it matters

Potential benefit: If successful, the project could lead to earlier, more accurate malaria detection and more effective interventions to prevent transmission.

How similar studies have gone: Previous malaria surveillance work has shown that integrating molecular methods improves detection of hidden infections and informs control measures.

Where this research is happening

  • University of Florida
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Dinglasan, Rhoel David Ramos — University of Florida
  • Study coordinator: Dinglasan, Rhoel David Ramos

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.