Administrative supplement to advance mapping of nervous system in knee and jaw osteoarthritis
Official title: Administrative Supplement for UF-Pitt REJOIN Team
Funded at University of Florida · NIH-11550511 · Data updated 2026-11-12
A supplemental NIH grant helps UF-Pitt expand advanced 3-D mapping of how nerves relate to chronic knee and jaw osteoarthritis using rat models and human samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 23, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $377,590 |
| NIH project number | 3UC2AR082196-02S1 |
| Project ID | NIH-11550511 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with knee OA or TMJ OA who may contribute tissue samples or participate in related studies.
✕Less likely to help
Direct benefits to patients may be limited during the grant period while the work is basic-science and methodological.
What this research studies
This supplement supports expanding data storage, reagents, sequencing, and tissue preservation so researchers can continue to map nerve pathways in knee and TMJ OA. The project combines animal models with human clinical samples to study how nerves relate to pain. It does so with improved imaging, molecular profiling, and behavior studies to uncover pathology-pain connections. The work builds on the parent REJOIN project without changing its scientific aims or protocols.
Why it matters
Potential benefit: If successful, patients with knee or TMJ OA could see better understanding of pain mechanisms and potentially more targeted therapies.
How similar studies have gone: Prior similar approaches have shown promise in linking nerve changes to pain in OA, but this supplement focuses on operational needs to scale those analyses.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Allen, Kyle D — University of Florida
- Study coordinator: Allen, Kyle D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.