Connecting Black and Hispanic adults with cancer to clinical trials using a culturally tailored online portal
Official title: Precision Clinical Trial Recruitment to Promote Cancer Health Equity Across Florida
Run by University of Florida · NCT05655494 · Data updated 2026-11-12
This project tests whether a tailored online portal with virtual community health educators can help Black and Hispanic adults with cancer find and get referred to cancer clinical trials.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | University of Florida Academic / other |
| Locations | 3 sites (Gainesville, Florida and 2 other locations) |
| Status | Recruiting |
| Started | May 20, 2025 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | November 5, 2026 |
| Trial ID | NCT05655494 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Black or Hispanic adults (18–100) with cancer who live in Florida, can read English or Spanish at about an eighth-grade level, have an email or text capability, and agree to be re-contacted.
✕Probably not a fit
People who live outside Florida, cannot read English or Spanish at the required level, lack email/text access, are under 18, or decline re-contact are unlikely to benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Racial and ethnic minority adults are underrepresented in cancer clinical trials, often due to low trust and multilevel access barriers. This pilot uses the ALEX Research Portal to consolidate referral channels and offer two approaches: a stand-alone portal and the portal augmented with virtual community health educator (vCHE) avatars and follow-up video visits. Clinicians, community health educators, patients, and family members can use the portal to find culturally tailored information and create referrals to NCI-supported trials, while investigators track referral and engagement outcomes. The project will be implemented at three Florida sites and focuses on English- or Spanish-speaking Black and Hispanic adults with cancer.
Why it matters
Potential benefit: If successful, the portal could increase culturally relevant information and referrals to cancer clinical trials for Black and Hispanic patients, improving access and representation.
How similar studies have gone: Prior work shows community health educator and digital navigation approaches can improve trust and trial enrollment among underserved populations, but combining a tailored portal with vCHE avatars is a relatively new, less-tested approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * An adult 18 to 100 years of age, * Able to read English or Spanish at least an eighth-grade level, * From a racial/ethnic background historically underrepresented in cancer clinical trials (e.g. Blacks or African Americans and/or Hispanics or Latinos), * Have an email account or the ability to receive texts, * Willingness to be re-contacted, * Be a resident of the state of Florida. Exclusion Criteria: * Unable to read English or Spanish at least at eighth-grade level * Does not have an email account or the ability to receive texts * Unwilling to be re-contacted * Non resident of the state of Florida.
Where it's running
-
Mayo Clinic in Florida
Jacksonville, Florida, United States Recruiting -
University of Florida
Gainesville, Florida, United States Not yet recruiting -
University of Miami
Miami, Florida, United States Not yet recruiting
Study contacts
- Principal investigator: Janice Krieger, PhD — Mayo Clinic
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.