Understanding pain processing in fibromyalgia and rheumatoid arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the mechanisms of pain processing in patients with fibromyalgia and rheumatoid arthritis. It focuses on how these conditions may share overlapping pain mechanisms, leading to both nociceptive and nociplastic pain experiences. By analyzing patients who meet specific criteria for these chronic pain syndromes, the study seeks to deepen the understanding of pain mechanisms and their implications for treatment. The study will include participants aged 18-70 who fulfill established diagnostic criteria for fibromyalgia and rheumatoid arthritis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ages 18-70
* Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
* Fulfills the 2010 ACR-EULAR classification criteria for RA
* Healthy volunteers: No significant pain/fatigue/depression/anxiety.

Exclusion Criteria:

* Diabetes
* Cancer
* Advanced liver, kidney or cardiovascular disease
* Neuropathic pain

Where it's running

• University of Florida
  Gainesville, Florida, United States Recruiting

Study contacts

• Principal investigator: Roland Staud, M.D. — University of Florida
• Study coordinator: Roland Staud, M.D.
• Email: staudr@ufl.edu
• Phone: 352-294-8200

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.