Exercise program for breast cancer survivors
Official title: Indoor Rowing as a Novel Exercise Therapy for Cardiovascular Rehabilitation in Middle-Aged and Older Breast Cancer Survivors Following Chemotherapy
Run by University of Florida · NCT05848141 · Data updated 2026-11-12
This study tests whether a rowing exercise program can help breast cancer survivors improve their heart health after finishing treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 80 Years |
| Sex | Women only |
| Enrollment | 72 (estimated) |
| Sponsor | University of Florida Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy, radiation |
| Locations | 1 site (Gainesville, Florida) |
| Status | Recruiting |
| Started | February 26, 2024 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | August 27, 2026 |
| Trial ID | NCT05848141 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are female breast cancer survivors aged 40 to 80 who have completed their treatment within the last 6 to 24 months.
✕Probably not a fit
Patients currently undergoing treatment for breast cancer or those with advanced lymphedema may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of a novel exercise intervention specifically designed for breast cancer survivors who have completed their treatment. It aims to assess how rowing as a form of cardiovascular rehabilitation can reduce the risk of cardiovascular disease in this population. Participants will engage in structured exercise training to evaluate improvements in their cardiovascular health. The study focuses on women aged 40 to 80 who have been cancer-free for 6 to 24 months after treatment.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce cardiovascular disease risk among breast cancer survivors.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions in cancer survivors, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of primary invasive non-metastatic breast cancer, stages I-III * female based on biological sex * 40 to 80 years of age * completed breast cancer treatment 6 to 24 months prior to study enrollment. Adjuvant endocrine therapy for breast cancer (e.g., ovarian suppression, SERMs, SERDs, AIs), CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed within 6 months prior to study enrollment and during study participation * absence of contraindications to exercise or study participation * study clinician approval Exclusion Criteria: * do not meet inclusion criteria * receiving or scheduled to receive treatment for breast cancer (i.e., chemotherapy, surgery, or radiation) during study participation is not allowed. Adjuvant endocrine therapy, CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed during study participation * lymphedema stage ≥ 2 prior to study enrolment * any relevant cardiovascular diseases (stroke, heart failure, myocardial ischemia during maximal graded exercise test, myocardial infarction, angina pectoris, coronary artery bypass surgery or angioplasty or coronary stent) * current participation in other experimental interventions that may confound interpretation of study findings (e.g., dietary intervention for weight loss) * consistent participation in ≥150 min/week of moderate-intensity rowing exercise training in previous 6 months
Where it's running
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Integrative Cardiovasculal Physiology Laboratory, University of Florida
Gainesville, Florida, United States Recruiting
Study contacts
- Principal investigator: Demetra Christou, PhD — University of Florida
- Study coordinator: Demetra Christou, PhD
- Email: ddchristou@ufl.edu
- Phone: 352-294-1746
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.