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Clinical trials and research at Universitaire Ziekenhuizen KU Leuven
As of November 12, 2026, Find a Trial lists 147 clinical trials run by Universitaire Ziekenhuizen KU Leuven that are recruiting, at sites in 11 countries (most in Belgium (145), Netherlands (6), Germany (3)). 4 were first registered in the last 30 days. By phase: Phase 2 (7), Phase 4 (6), Phase 2/3 (5), Phase 3 (4). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 147Clinical trials
- 4New in 30 days
- 11Countries
Newest trials
All recruiting trials (147)
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Outdoor resistance training for older adults
This trial tests a 6-week outdoor strength program using benches and a smartphone app to see if it’s safe, usable, and appealing for community-dwelling adults aged 65 and older.
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Sarcopenia in Patients After Cardiac Surgery
This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.
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Imaging endometriosis with a special PET tracer in adult women
This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.
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GLP-1 weight‑loss medicine: finding who will benefit most
This study tests whether a GLP-1 drug called semaglutide helps with weight loss by changing eating behavior, to see which people it helps the most.
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AI-guided treatment choices for advanced liver cancer
Researchers are testing an AI tool to help predict which patients with advanced hepatocellular carcinoma will respond to modern systemic therapies.
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Quality of Life and Functional Status in Adults with Spinal Deformity
This study tests how imaging, pain, daily functioning, and psychosocial factors relate to quality of life in adults with spinal deformity across three care paths (conservative care, first corrective surgery, or reoperation).
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Access to Innovative Cancer Treatments for Children and Young People in Belgium
This observational study collects safety and effectiveness data on off‑label and compassionate cancer medicines used in kids and young adults up to age 25 in Belgium.
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Short-chain fats to calm inflammation after a small immune challenge
This study tests whether taking colon-delivered short-chain fatty acids can dampen inflammation and mood/mental performance changes after a controllable immune trigger in healthy adults.
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Blood-based biomarkers for Alzheimer’s disease in primary care
This study tests whether a blood test for ps-tau217 and the ps-tau217/Aβ42 ratio can help primary care patients with cognitive concerns understand their situation.
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Chronic Postoperative Pain after Cardiac Surgery: Incidence and Impact
This survey checks how often people have chronic pain 3 months after cardiac surgery and who it affects most, to see if the rate is lower than 33%.
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Mpox sample collection with SDS-EDTA paper strips in DRC
A study tests whether SDS-EDTA-treated chromatography paper strips can collect mpox samples as well as standard swabs for lab testing in people with suspected mpox in South Kivu, DRC.
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Improving Immunotherapy Use in Liver Cancer
This study tests whether biomarkers can identify hepatocellular carcinoma patients who are more likely to respond to immunotherapy.
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Wideband tympanometry to measure how well speech passes through the middle ear
This trial will see if wideband tympanometry can measure how well speech travels through the middle ear in adults with conductive hearing loss, normal-hearing adults, and cochlear implant recipients.
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FAPI‑74 PET/CT versus FDG PET/CT for inflammation in FUO, IgG4‑RD, and axial spondyloarthritis
This project will test whether [18F]-AlF-FAPI-74 PET/CT finds inflammation more accurately than standard [18F]-FDG PET/CT in people with fever of unknown origin, IgG4‑related disease, or axial spondyloarthritis.
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Can infrared thermography help predict how skin wounds heal after surgery?
This study tests if a harmless infrared camera can spot early signs of wound problems after skin surgery so clinicians can act sooner.
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Ultra-high-resolution PET imaging of aging, neurodegeneration, and psychotic disorders
We will test whether ultra-high-resolution PET and 3T MRI scans can reveal early brain and spinal cord changes in healthy adults and people with Alzheimer's, Parkinson's disease, ALS, PSP, REM sleep behavior disorder, or psychotic disorders.
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5C MEDic Knee System after knee replacement
This study tests the safety and real-world use of the 5C MEDic knee implant in adults undergoing knee replacement and tracks any device-related problems over time.
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Altered Joint Mechanics and Biological Response in Osteoarthritic Knees
This study tests how braces or high tibial osteotomy (HTO) affect knee bone and cartilage in people with knee OA who are scheduled for corrective treatment.
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Long-term Aseptic Revision & Advanced Hip Arthroplasty Database (patient registry)
A prospective database is being collected to track complex hip replacements and revisions to see which implants and approaches work best for younger patients and complicated cases.
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Healthy Caucasian knee anatomy and function database
This project will collect high-resolution CT, weightbearing full-leg X-rays (EOS), and ultrasound tests from healthy 20–35 year-old people of European/Caucasian descent to create a large database of knee anatomy and function.
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Stepwise introduction of heat-treated cow's milk to build tolerance after previous treatment didn't work
We will follow children with cow's milk allergy who can drink heated milk but still react to regular milk to see how long it takes them to become fully tolerant.
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Gum recession in adults with and without prior orthodontic treatment
We will test which patient and tooth factors increase the chance of gum recession in adults who have or have not had orthodontic treatment.
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Enhanced recovery pathway for burr-hole drainage in chronic subdural hematoma patients
This project tests whether an enhanced recovery protocol for adults having burr-hole drainage for chronic subdural hematoma can reduce recurrence and complications compared with past patients.
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Flecainide safety in people with atrial fibrillation and stable coronary artery disease
This study tests whether flecainide is as safe as standard rhythm-control drugs for adults with atrial fibrillation and stable coronary artery disease.
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Collecting colonoscopy images of large colorectal polyps for AI development
This project will try to collect colonoscopy images and videos of large colorectal polyps from adults undergoing colonoscopy to help build an AI that predicts polyp histology and depth of invasion.
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Measuring Hsp90 levels in the human brain
This trial tests whether a PET tracer called [11C]HSP990 can measure Hsp90 levels in the brains of healthy adults and people with Parkinson's disease, Alzheimer's disease, or ALS.
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CPAP-assisted radiotherapy to lower heart and lung dose after breast-conserving surgery
This tests whether wearing a CPAP breathing device during adjuvant radiotherapy can lower radiation exposure to the heart and lungs for women with early-stage (stage 1–3) breast cancer who had breast‑conserving surgery.
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XEN‑63 Gel Stent versus PRESERFLO MicroShunt for lowering eye pressure in open‑angle glaucoma.
This trial tests whether the PRESERFLO MicroShunt is at least as good as the XEN‑63 Gel Stent at lowering eye pressure over 12 months in adults with open‑angle glaucoma who need surgery.
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Micra AV2 leadless pacemaker to improve AV synchrony in AV block
This study will test whether the Micra AV2 leadless pacemaker improves AV synchrony and is safe for adults with high‑degree AV block who have normal sinus rhythm.
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Personalized discharge letters for low-risk skin cancer patients
Researchers are testing if tailored discharge letters, with or without visual aids, help low-risk skin cancer patients understand their care and follow-up better after a dermatology visit.
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R³ rehabilitation pathway versus usual care after lumbar nerve-root surgery
This program tests whether a structured R³ rehab pathway helps adults aged 18–65 having lumbar nerve-root surgery return to work faster than usual care.
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Using biological materials to repair bone defects around teeth
This study will test whether enamel matrix, hyaluronic acid, platelet‑rich fibrin, or a bone graft can help repair intra‑bony defects around teeth in adults with periodontitis who need minimally invasive gum surgery.
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Digestion and gut function after bariatric surgery
This project will test how digestion — including enzymes, bile acids, pH, and transit time — works in adults with obesity and in people at least one year after Roux‑en‑Y or sleeve gastrectomy by collecting intestinal samples and using a swallowable sensor capsule.
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Lifestyle program to improve outcomes in dichorionic twin pregnancies
This program will test whether a combined nutrition, exercise, and mindfulness plan for people pregnant with dichorionic twins can extend pregnancy and reduce preterm birth.
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Raising pacemaker heart rate during light exercise to lower left-heart pressures in HFpEF
This test will try whether temporarily increasing the heart rate by adjusting pacemaker settings during light exercise can lower left-heart filling pressures and improve cardiac output in people with HFpEF who already have a DDD pacemaker.
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Free vitamin D and steroid metabolism in endocrine and kidney conditions
This project will measure free (unbound) vitamin D and related steroid hormones in adults — including healthy people, pregnant women, and patients with endocrine or kidney disorders — to see how processing differs between groups.
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Biobank for skin cancer collecting blood, tissue, and clinical data
This project will collect blood, tissue, and clinical information from adults with melanoma or non‑melanoma skin cancer to build a biobank for future research.
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Ex vivo testing of JAK inhibitors and a gene-therapy approach for JAK-STAT related immune disorders
This project will try JAK-inhibitor drugs and a gene-therapy approach on blood samples from adults with JAK-STAT pathway primary immunodeficiencies and healthy controls to see how immune cells and gene expression change.
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Guided breathing to improve stress and heart rate variability in autistic young adults
This study will test two guided breathing exercises to see if they reduce stress and improve heart rate variability in autistic people aged 16–25.
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How spicy compounds affect blood flow in the feet
This research will see if applying cinnamaldehyde, AITC, or capsaicin to the feet of healthy adults changes skin blood flow and whether those responses are consistent across doses, between feet, and across visits.
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Robotic versus laparoscopic colorectal surgery for people with IBD
Adults with IBD who need elective colorectal surgery will be randomly assigned to robotic or conventional laparoscopic surgery to see if robotic surgery reduces complications and improves recovery and quality of life.
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Belgian Amyloidosis Biobank and Patient Registry at UZ Leuven
This project collects and stores blood, tissue samples, and medical data from adults with suspected or confirmed amyloidosis to create a biobank and registry for future research.
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PET/MRI with [18F]AlF-NOTA-octreotide to image inflammation in carotid artery plaque
This will test whether [18F]AlF-OC PET/MRI can measure inflammation in carotid plaques and help predict recurrent stroke or TIA in people who recently had a carotid-territory stroke or high-risk TIA with at least 30% carotid stenosis.
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Photon-counting CT with intracoronary imaging for detailed coronary plaque characterization
This will test whether ultra–high-resolution photon-counting CT can reliably characterize coronary plaque compared with OCT and IVUS in adults with acute or chronic coronary syndrome, including patients with suspected in-stent restenosis or prior PCI for chronic total occlusion.
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Exploring muscle properties in children with spastic cerebral palsy
This study is trying to see how the muscles of children with spastic cerebral palsy are different from those of kids without the condition, using special imaging techniques to look at things like muscle size and fat content.
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Ultrasound-guided aspiration of cystic pelvic lesions
This study is testing if using ultrasound to drain cysts in the pelvis can help premenopausal women feel better compared to traditional surgery.
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Mapping sensory pain patterns in ADPKD
This project will test whether detailed sensory testing and short questionnaires can identify characteristic pain patterns in people aged 12 and older with ADPKD compared with matched healthy volunteers.
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Zolbetuximab with paclitaxel and ramucirumab for CLDN18.2-positive stomach and gastro‑esophageal junction cancer
This treatment tests whether adding zolbetuximab to paclitaxel and ramucirumab helps adults with metastatic gastro‑esophageal adenocarcinoma whose tumors are CLDN18.2‑positive live longer.
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Evaluating ultrasound for diagnosing Dupuytren's disease
This study is testing if ultrasound can help doctors better diagnose Dupuytren's disease in patients by providing more detailed information about their condition.
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Guselkumab and diet for chronic or relapsing pouchitis
This project will test whether the drug guselkumab plus a high-fruit, low ultra-processed-food diet helps adults with chronic or relapsing pouchitis.
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Combining a very low calorie ketogenic diet with naltrexone/bupropion for weight regain after bariatric surgery
This study is testing if a very low calorie ketogenic diet combined with a medication can help people who have regained weight after bariatric surgery lose weight again.
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Long-term brain imaging of synapses in Parkinson's disease
This project will use PET and MRI scans to see if synapse loss spreads from the brainstem to the cortex over time and whether cortical synapse loss is linked to thinking decline in people with Parkinson's disease.
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Investigating the effects of endoscopic skull base surgery on smell
This study tests how endoscopic skull base surgery affects the sense of smell in patients to better understand any smell-related problems that might happen after the surgery.
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Investigating protein needs after gastric bypass surgery
This study tests how much protein adult men need after having gastric bypass surgery to see if their needs are different from those of the general population.
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Budesonide treatment for functional dyspepsia
This study is testing if Budesonide can help people with functional dyspepsia feel better by reducing inflammation in their digestive system.
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Lifestyle program to boost pre-surgery treatment for early triple-negative breast cancer
This will test whether adding cycles of a fasting-mimicking diet plus supervised exercise to standard pre-surgery chemo-immunotherapy helps people with early triple-negative breast cancer respond better, tolerate treatment, and have a better quality of life.
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Neoadjuvant dostarlimab before surgery for resectable stage III pMMR/MSS colon cancer
This will test whether two pre-surgery infusions of the PD-1 drug dostarlimab help people with resectable stage III pMMR/MSS colon cancer.
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Monitoring non-invasive ventilation at home for patients with Duchenne muscular dystrophy
This study is testing whether using video and CO2 monitoring at home can help track how well non-invasive ventilation works for people with Duchenne muscular dystrophy.
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Tool to remove incorrect antibiotic allergy labels in hospitalized adults
This project will test a non-invasive 'AAL-fact-check' that uses a questionnaire, electronic health record review, and contact with primary care to see if hospitalized adults with a beta-lactam allergy label can have that label removed or refined so doctors can choose better antibiotics.
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Muscle, tendon, and nerve changes after botulinum toxin injections for post-stroke spastic equinovarus
This pilot will use 3D ultrasound and instrumented spasticity tests to see how botulinum toxin injections change muscle, tendon, and nerve properties in adults with post-stroke spastic equinovarus.
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Evaluating long-term outcomes of stereotactic radiotherapy for ventricular tachycardia
This study is testing if a special type of radiation treatment can help people with hard-to-treat ventricular tachycardia feel better and stay safe over the long term.
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Effects of nitrogen pollution on pollen allergies in Belgium
This study is testing how nitrogen pollution affects allergy symptoms in people who are sensitive to pollen in Belgium.
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Evaluating the effectiveness of biologics for chronic rhinosinusitis with nasal polyps
This study is testing how well biologic treatments work for adults with chronic rhinosinusitis and nasal polyps to see if they are more effective than standard treatments.
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Using radiotherapy to treat advanced heart failure
This study is testing if a single low dose of radiation therapy can help people with advanced heart failure feel better and improve their heart function.
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Effects of inflammation on stress responses in healthy men
This study is testing how inflammation affects stress responses in healthy men by giving them an injection that causes inflammation and then observing their brain activity during stress tasks.
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Treatment for prostate cancer with limited metastasis
This study is testing whether a new treatment for prostate cancer with a few spreading spots can help patients live longer by comparing radiotherapy to surgery.
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Understanding muscle properties in children with cerebral palsy
This study is trying to understand the tiny details of muscles in children with cerebral palsy to see how they relate to their overall muscle health and treatment results.
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Investigating how ankle-foot orthoses affect muscle activity in children with cerebral palsy
This study is testing how ankle-foot braces can change muscle activity in children with cerebral palsy while they walk to help improve their mobility.
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Assessing portal pressure response to beta-blockers using endoscopic ultrasound
This study is testing if using endoscopic ultrasound to measure portal pressure can help doctors see how well beta-blockers work for people with cirrhosis and high blood pressure in the liver.
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Rikkunshi-to for primary care dyspepsia
This trial tests whether the herbal medicine rikkunshi-to can relieve symptoms in adults with functional dyspepsia, including postprandial distress syndrome.
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Investigating olfactory dysfunction after COVID-19 infection
This study is trying to understand why some people still have trouble smelling after recovering from COVID-19 by looking at samples from their noses.
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Assessing the effectiveness of teclistamab for multiple myeloma
This study is testing if teclistamab can help people with relapsed or hard-to-treat multiple myeloma who have already tried at least three other treatments.
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Registry for patients with smell and taste disorders
This study is trying to understand how common smell and taste problems are in people from Belgium and Flanders, especially after COVID-19, by having participants take tests and answer questions about their experiences.
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Investigating brain activity and consciousness in patients with severe brain injuries
This study is testing a new way to monitor brain activity in patients with severe brain injuries to see if it can help doctors understand their level of consciousness and improve their treatment.
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Quilting sutures after mastectomy to improve recovery
This study is testing if a special type of stitching after breast surgery can help women recover better and avoid complications compared to regular stitching.
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Effect of heated foods on remission in children with Eosinophilic Esophagitis
This study is testing if giving heated versions of hen's egg and cow's milk can help children with Eosinophilic Esophagitis stay in remission and possibly build tolerance to these foods.
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Introducing heated cow's milk to help children with milk allergies develop tolerance
This study is testing if slowly introducing less heated cow's milk to children with milk allergies can help them develop a tolerance faster and improve their quality of life.
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Bacteriophage therapy for hard-to-treat infections
This study is testing if a new treatment using bacteriophages can help people with tough infections that don’t respond to regular medicines.
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Combining bicalutamide and abemaciclib for advanced androgen receptor-positive triple-negative breast cancer
This study is testing if combining two medications, bicalutamide and abemaciclib, can help people with advanced triple-negative breast cancer feel better after their previous treatments.
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Understanding why some breast cancer patients feel swelling without measurable lymphedema
This study is trying to understand why some breast cancer patients feel swelling in their arms or chest even when tests show they don't have lymphedema, to help improve their care.
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Treatment for early Dupuytren's disease using vitamin E cream
This study is testing if using vitamin E cream can help people with early Dupuytren's disease stop their fingers from getting worse.
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Using continuous glucose monitoring for women with gestational diabetes
This study is testing whether using a continuous glucose monitor can help women with gestational diabetes manage their blood sugar better during and after pregnancy compared to regular blood sugar checks.
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Home-based exercise program for liver transplant recipients
This study is testing whether different levels of exercise at home can help people who have recently had a liver transplant feel better and improve their health over six months.
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Investigating the biomechanics of femoroacetabular impingement and its effects
This study tests how the way your hip moves affects pain and symptoms in people with femoroacetabular impingement to help improve diagnosis and treatment.
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Temporary artery clipping during robot-assisted myomectomy for fibroids
This study is testing if temporarily clipping certain blood vessels during robot-assisted surgery for fibroids can help reduce bleeding and improve recovery for women undergoing the procedure.
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Characterizing the biomechanics and morphology of posterior tibial tendon dysfunction
This study is trying to better understand the changes in the foot caused by posterior tibial tendon dysfunction to help doctors make better treatment choices for patients dealing with this painful condition.
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Evaluating brain blood flow regulation in infants with congenital heart disease
This study looks at how blood flow to the brain works in infants with congenital heart disease to see if it affects their brain development and helps create better follow-up care for them.
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Evaluating shoulder joint contact patterns in osteoarthritis patients
This study looks at how the shoulder joint works in people with arthritis before and after they have shoulder replacement surgery to see if it can help improve their recovery.
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Investigating the role of micronerves in Dupuytren's disease and their impact on recurrence
This study looks at whether tiny nerve bundles in the hand affect how often Dupuytren's disease comes back after surgery in people with this condition.
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Understanding Basal Cell Function in Chronic Rhinosinusitis with Nasal Polyps
This study is trying to understand how certain cells in the nose work differently in people with chronic sinus issues and nasal polyps compared to healthy individuals.
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Comparing imaging techniques for diagnosing Parkinson's disease and related conditions
This study is testing two different imaging techniques to see which one better helps doctors tell apart Parkinson's disease, multiple system atrophy, dementia with Lewy bodies, and Alzheimer's disease in patients and healthy volunteers.
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Adding tongue scraping to initial periodontal therapy to reduce bad breath
This will see if adding daily tongue scraping to standard initial periodontal treatment reduces bad breath in adults with generalized periodontitis.
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Nutritional supplements for muscle growth in children with spastic cerebral palsy
This study is trying out a 10-week nutritional supplement plan with leucine to see if it helps children with spastic cerebral palsy grow stronger muscles.
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Revitalizing traumatized immature permanent teeth
This study is testing how well revitalization treatments work for young permanent teeth that have been injured, with or without infection, to see if they can heal and develop properly over three years.
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Study on how medicines affect breastfeeding and infant exposure through human milk
This study is trying to see how different medicines affect breast milk and how much of those medicines babies might get when breastfeeding.
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Investigating imaging techniques for diagnosing non-convulsive status epilepticus
This study is testing three different imaging techniques to see which one best helps doctors diagnose non-convulsive status epilepticus in patients.
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Optimizing Rituximab Tapering Strategies for Rheumatoid Arthritis
This study is testing two different ways to reduce the dose of rituximab in people with rheumatoid arthritis to see which method helps them feel better and manage their condition more effectively.
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Optimizing ECT for difficult-to-treat depression
This study is testing whether sticking with one type of electroconvulsive therapy or switching to another can help people with tough-to-treat depression recover faster and with less impact on their thinking.
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Using abemaciclib and letrozole for treating rare estrogen receptor-positive ovarian cancer
This study is testing if the combination of two drugs, abemaciclib and letrozole, can help people with rare types of estrogen receptor-positive ovarian cancer that haven't responded to previous treatment.
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Evaluating the DOMINO Diet App for Irritable Bowel Syndrome
This study is testing if using the DOMINO diet app can help people with Irritable Bowel Syndrome manage their symptoms by following a low FODMAP diet.
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Comparing immediate and delayed surgery for ACL injuries
This study tests whether having surgery right away or waiting to see if it's needed later is better for people with ACL injuries.
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Impact of Radiotherapy on Neurocognition in Brain Tumor Patients
This study is testing how radiotherapy affects thinking and memory in adults with brain tumors over time to see if certain treatments lead to cognitive decline.
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Registry of overweight and obese adults with type 1 diabetes
This study is creating a registry of overweight and obese adults with type 1 diabetes to see how their weight affects their diabetes management and health outcomes.
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Testing blood samples for esophageal cancer treatment
This study is testing if blood tests can help track the progress of esophageal cancer treatment in patients who have had surgery.
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Effects of rifaximin on gut bacteria and emotional responses
This study is testing if the antibiotic rifaximin can change gut bacteria and affect how healthy men respond to stress and fear.
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Using semaglutide to prevent type 2 diabetes in women with past gestational diabetes
This study is testing if the medication semaglutide can help women who had gestational diabetes lower their chances of developing type 2 diabetes after giving birth.
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Comparing two PET imaging techniques in Huntington Disease
This study is testing two different PET imaging techniques to see which one better shows changes in the brain of people with Huntington Disease and how those changes relate to movement problems.
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Treatment for recurrent prostate cancer with metastases
This study is testing whether combining hormone therapy with targeted radiation or surgery can help men with recurrent prostate cancer live longer without their cancer spreading.
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Observational study on extreme hypofractionation for localized prostate cancer
This study tests a new type of radiation treatment for men with localized prostate cancer to see if giving higher doses in fewer sessions can work better and be safer than the usual methods.
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Studying brain activity in epilepsy using micro-electrodes
This study is testing how tiny electrodes implanted in the brain can help researchers understand brain activity in people with epilepsy and identify the areas that trigger seizures.
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Impact of Lymphoedema and Urinary Issues After Cancer Surgery
This study looks at how common swelling in the legs and urinary problems are after cancer surgery to see if certain tests can help catch these issues early and improve life for patients.
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Examining muscle growth in infants and young children with spastic cerebral palsy
This study looks at how muscle growth changes in infants and young children with spastic cerebral palsy to see if these changes can help improve their treatment and outcomes.
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Comparing two methods of biological therapy to prevent Crohn's disease recurrence after surgery
This study is testing whether a new way of giving biological therapy during endoscopy can help prevent Crohn's disease from coming back after surgery, compared to the usual method, for people who have had their intestines operated on.
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Investigating the heart health of young competitive endurance athletes
This study looks at how training and genetics affect the heart health of young athletes aged 14-23 who compete in endurance sports to see what long-term impacts intense training might have.
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Long-term follow-up of patients with recent onset psoriasis
This study is tracking people who have had psoriasis for less than three years to see how the disease changes over time and to find clues that might predict more serious problems later on.
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Impact of Bariatric Surgery on Pregnancy and Glucose Levels
This study is testing how pregnancy and blood sugar levels are affected in women who have had weight loss surgery compared to those who haven't, to see if it helps with pregnancy outcomes.
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Reconstructive lymphatic surgery for treating lymphoedema
This study tests if adding reconstructive lymphatic surgery to regular treatment can help people with lymphoedema in their arms or legs feel better and improve their quality of life.
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Evaluating quality of life and functional outcomes in sarcoma patients after limb salvage surgery
This study looks at how limb salvage surgery affects the quality of life and daily functioning of people aged 18 to 95 who have had surgery for bone or soft tissue sarcoma in their legs.
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Long-term follow-up for hip prosthetic joint infections at University Hospitals Leuven
This study looks at patients with hip joint infections after surgery to see how well different treatments work over time.
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Using SBRT to treat spinal metastases from solid tumors
This study is testing if a special type of radiation treatment called SBRT can help people with spinal tumors that are pressing on their spinal cord feel better and improve their quality of life.
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Using a 3D foot model to assess outcomes after ankle and hindfoot surgery
This study is testing a new 3D foot model to see how well ankle and hindfoot surgeries work by looking at how people walk and how pressure is distributed on their feet after the surgery.
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Looking at balance and movement in adults with sagittal spinal misalignment
This project will try using 3D imaging and motion analysis to see how adults aged 45+ with sagittal plane spinal misalignment stand and walk compared with people without deformity.
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3D and motion-informed guidance for choosing scoliosis surgery
This project will try using 3D imaging and movement-based mechanical information to help decide between vertebral body tethering or spinal fusion for adolescents and young adults with idiopathic scoliosis treated at UZ Leuven.
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Surgery vs. conservative treatment for foot drop caused by peroneal nerve entrapment
This study is testing whether surgery or physical therapy works better for people with ongoing foot drop caused by nerve issues.
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Registry for prostate cancer and patient-reported outcomes
This study is testing a new digital tool to help track how men with localized or locally advanced prostate cancer feel and respond to treatment over time.
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Reducing radiation for head and neck cancer treatment
This study is testing if using a special mapping technique can help reduce the amount of radiation needed for patients with head and neck cancer while still effectively treating their disease.
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Measuring balance and trunk strength in adults with spinal deformity
See if new balance tests and trunk-strength measurements can show functional differences between adults with spinal deformity and people without deformity.
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Registry for inguinal and femoral hernia surgical outcomes
This study is trying to see how well surgery for inguinal and femoral hernias works by looking at pain levels and patient satisfaction one year after the operation.
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Registry for Hirschsprung Disease in Belgium
This study is collecting information about children in Belgium who have had surgery for Hirschsprung disease to see how their bowel habits change over time and to find ways to improve their care.
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Registry of patients visiting the Obesity Clinic
This study is creating a registry of people visiting the Obesity Clinic to gather information that can help improve treatment and care for obesity.
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Evaluating the Nasal Allergen Provocation Test for Allergen Immunotherapy
This study is trying to see how well a nasal allergy test works for people starting treatment for allergic rhinitis and if it can help improve their care over time.
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Post-mortem tissue donation program for breast cancer research
This program is collecting tissue samples from patients with metastatic breast cancer to help researchers learn more about how the cancer develops and why some treatments don’t work.
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Evaluating the effects of cinnamaldehyde and capsaicin on blood flow in patients with chemotherapy-induced peripheral neuropathy
This study tests if applying cinnamaldehyde and capsaicin on the skin can improve blood flow in patients with chemotherapy-induced peripheral neuropathy and healthy volunteers.
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In-depth investigation of the immune response to COVID-19
This study looks at the immune responses of hospitalized COVID-19 patients to see what makes some people get sicker than others.
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Comparing long-term and short-term hormone therapy with radiation for prostate cancer
This study is testing whether long-term or short-term hormone therapy combined with radiation helps men with prostate cancer who have had surgery and are experiencing a return of the disease.
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Comparing surgical techniques for treating endometriomas
This study is testing which of two surgical methods is better at preserving a woman's ability to have children while treating endometriomas.
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Ketogenic diet and ketone ester to reduce arm lymphedema
This trial will test whether a ketogenic diet, with or without ketone ester supplements, can reduce swelling in adults with recent unilateral arm lymphedema after lymph node removal.
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Collecting data for bladder cancer patients
This study is collecting information from bladder cancer patients to help improve future treatments and understand how the disease behaves.
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Genetic testing to improve pregnancy rates in women with repeated implantation failure
This study tests if a genetic test for embryos can help women who have had multiple failed pregnancies get pregnant more easily and have healthier pregnancies.
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Long-term analysis of quality of life in glioma patients
This study is trying to see how living with glioma, a type of brain tumor, affects patients' quality of life over time, using a detailed questionnaire to gather information.
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Investigating the link between influenza and invasive pulmonary aspergillosis
This study looks at how having the flu affects patients with severe pneumonia in the ICU and whether it leads to more serious lung infections.
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Registry for transcatheter valve treatments in heart valve diseases
This study looks at how safe and effective new heart valve treatments are for people with heart valve diseases to help improve their care and quality of life.
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Registry for patients with central sleep apnea in Belgium
This study is collecting information from patients with central sleep apnea in Belgium to see how different factors affect their treatment choices and how well they stick to their treatment plans.
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Identifying genetic factors for pulmonary arterial hypertension in congenital heart defects
This study is trying to find out if certain gene changes in people with congenital heart defects can lead to pulmonary arterial hypertension, to help catch and treat it earlier.
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Comparing two endoscopic techniques for detecting cancer in ulcerative colitis patients
This study is testing if two different endoscopy techniques can better find cancer in people with long-term ulcerative colitis while reducing the need for random biopsies.
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Registering patients undergoing heated chemotherapy for peritoneal cancers
This study is collecting information from patients with certain abdominal cancers who are having surgery followed by heated chemotherapy to see if it helps them live longer and feel better.
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Biobank for kidney transplant donors and recipients
This study is setting up a collection of samples from kidney transplant donors and recipients to help researchers find ways to improve kidney transplant outcomes in the future.
Quick answers
How many clinical trials run by Universitaire Ziekenhuizen KU Leuven are recruiting right now?
147, as of November 12, 2026. 4 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in Belgium (145 trials), Netherlands (6 trials), Germany (3 trials), Australia (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 7, Phase 4: 6, Phase 2/3: 5, Phase 3: 4. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.