Characterizing the biomechanics and morphology of posterior tibial tendon dysfunction
Official title: Biomechanical and Morphological Characterization of the Foot in Patients With Posterior Tibial Tendon Dysfunction.
Run by Universitaire Ziekenhuizen KU Leuven · NCT06260813 · Data updated 2026-11-12
This study is trying to better understand the changes in the foot caused by posterior tibial tendon dysfunction to help doctors make better treatment choices for patients dealing with this painful condition.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven, Vlaams-Brabant) |
| Status | Recruiting |
| Started | August 22, 2022 |
| Main results expected | August 1, 2028 |
| Study ends | August 1, 2028 |
| Registry record updated | July 10, 2026 |
| Trial ID | NCT06260813 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18-675 with varying stages of posterior tibial tendon dysfunction.
✕Probably not a fit
Patients who are younger than 18, unable to walk without aids, or have significant leg length discrepancies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on posterior tibial tendon dysfunction (PTTD), a progressive condition that leads to severe foot deformities and pain. It aims to enhance clinical decision-making by integrating biomechanical and morphological characteristics into the existing classification system for PTTD. The study will utilize various imaging techniques, including radiography, ultrasound, MRI, and CT scans, along with gait analysis to assess the condition across different stages. By understanding these characteristics, the study seeks to improve treatment strategies for affected patients.
Why it matters
Potential benefit: If successful, this study could lead to more effective and personalized treatment options for patients with posterior tibial tendon dysfunction.
How similar studies have gone: While there is existing research on PTTD, this study's focus on integrating biomechanical and morphological assessments is a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Patient groups: * Posterior tibial tendon dysfunction (all clinical stages) * Age 18-675 year * ICF obtained * Control group: * No pain complaints * No pes plano valgus, PTTD or pes cavo varus or other foot and ankle pathology * Age 18-75 year * ICF obtained Exclusion criteria patient and control groups: * Being younger than 18 years * Inability to walk without mobility aids * Inability to walk \< 100 meter * Difference in leg length \> 3cm * Subjects with BMI\>30 kg/m², due to less accurate gait analysis by absence of anatomical landmarks * Subjects unable to perform a gait analysis * Any medical condition possibly affecting normal gait. * Pregnancy: at the start or during the study
Where it's running
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UZ Leuven
Leuven, Vlaams-Brabant, Belgium Recruiting
Study contacts
- Principal investigator: Sander Wuite — Universitaire Ziekenhuizen KU Leuven
- Study coordinator: Sander Wuite
- Email: sander.wuite@uzleuven.be
- Phone: +32 16 33 83 29
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.