Studying brain activity in epilepsy using micro-electrodes
Official title: Study of Brain Activity in Candidates for Epilepsy Surgery
Run by Universitaire Ziekenhuizen KU Leuven · NCT05307146 · Data updated 2026-11-12
This study is testing how tiny electrodes implanted in the brain can help researchers understand brain activity in people with epilepsy and identify the areas that trigger seizures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven) |
| Status | Recruiting |
| Started | December 18, 2013 |
| Main results expected | January 1, 2035 |
| Study ends | January 1, 2035 |
| Registry record updated | April 1, 2022 |
| Trial ID | NCT05307146 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have epilepsy and are scheduled for intracranial electrode placement.
✕Probably not a fit
Patients under 18 years of age or those who are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study aims to investigate brain activity in patients with epilepsy by implanting micro-electrodes for high-resolution recordings. The researchers will focus on identifying the epileptogenic network and understanding brain function during specific tasks. By utilizing both macro and micro-electrode arrays, the study seeks to capture neural signals at an unprecedented level of detail, even down to single neurons. The findings may contribute to advancements in brain-machine interface applications and improve our understanding of epilepsy.
Why it matters
Potential benefit: If successful, this study could lead to better-targeted treatments for epilepsy and improved brain-machine interface technologies.
How similar studies have gone: Other studies using similar high-resolution neural recording techniques have shown promise in understanding brain networks, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 yo * Epilepsy patients undergoing intracranial electrode placement. * Able to understand the procedure involved and to consent. Exclusion Criteria: * Age \< 18 yo * Pregnancy
Where it's running
-
UZ Leuven
Leuven, Belgium Recruiting
Study contacts
- Study coordinator: Anaïs Van Hoylandt
- Email: anais.vanhoylandt@uzleuven.be
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.