Studying brain activity in epilepsy using micro-electrodes
Study of Brain Activity in Candidates for Epilepsy Surgery
NA · Universitaire Ziekenhuizen KU Leuven · NCT05307146
This study is testing how tiny electrodes implanted in the brain can help researchers understand brain activity in people with epilepsy and identify the areas that trigger seizures.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Universitaire Ziekenhuizen KU Leuven (other) |
| Locations | 1 site (Leuven) |
| Trial ID | NCT05307146 on ClinicalTrials.gov |
What this trial studies
This interventional study aims to investigate brain activity in patients with epilepsy by implanting micro-electrodes for high-resolution recordings. The researchers will focus on identifying the epileptogenic network and understanding brain function during specific tasks. By utilizing both macro and micro-electrode arrays, the study seeks to capture neural signals at an unprecedented level of detail, even down to single neurons. The findings may contribute to advancements in brain-machine interface applications and improve our understanding of epilepsy.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have epilepsy and are scheduled for intracranial electrode placement.
Not a fit: Patients under 18 years of age or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better-targeted treatments for epilepsy and improved brain-machine interface technologies.
How similar studies have performed: Other studies using similar high-resolution neural recording techniques have shown promise in understanding brain networks, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 yo * Epilepsy patients undergoing intracranial electrode placement. * Able to understand the procedure involved and to consent. Exclusion Criteria: * Age \< 18 yo * Pregnancy
Where this trial is running
Leuven
- UZ Leuven — Leuven, Belgium (RECRUITING)
Study contacts
- Study coordinator: Anaïs Van Hoylandt
- Email: anais.vanhoylandt@uzleuven.be
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Epilepsy