Clinical trial Recruiting at 1 site Observational Ages 18 and up

Sarcopenia in Patients After Cardiac Surgery

Official title: Sarcopenia After Cardiac Surgery: An Overlooked Target for Therapeutic Optimization?

Run by Universitaire Ziekenhuizen KU Leuven · NCT07908472 · Data updated 2026-11-12

This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorUniversitaire Ziekenhuizen KU Leuven
Academic / other
Locations1 site (Leuven)
StatusRecruiting
StartedFebruary 5, 2026
Main results expectedJune 2028
Study endsJune 2028
Registry record updatedNovember 2, 2026
Trial IDNCT07908472 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) who have been hospitalized after cardiac surgery, are stable, and are eligible for cardiac rehabilitation after discharge.

Probably not a fit

Patients who do not undergo or complete cardiac rehabilitation or who have conditions making functional testing inappropriate may derive little benefit from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to measure the prevalence of sarcopenia in patients who have recently undergone cardiac surgery and to see if standard post-discharge care is sufficient to improve sarcopenia outcomes. Participants will be assessed for sarcopenia one day before hospital discharge and then again at 4 weeks, 16 weeks, and/or 1 year, depending on baseline status and participation in a cardiac rehabilitation program. The study follows existing guidelines on sarcopenia management and does not involve any experimental intervention. It describes real-world practice and associations between rehabilitation participation and sarcopenia trajectories in this population.

Why it matters

Potential benefit: If successful, the study could clarify whether current post-surgical care supports muscle health and guide improvements in rehabilitation strategies.

How similar studies have gone: There is prior evidence that sarcopenia is common in cardiovascular patients, but this study adds real-world post-surgical data and may be among the first to track longitudinal outcomes without an intervention.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Hospitalized following cardiac surgery (i.e. hospitalization unit 18 and 22)
* Stable with regard to symptoms
* Eligible for cardiac rehabilitation according to current guidelines following hospital discharge
* Voluntary written informed consent of the participant has been obtained
* At least 18 years of age at the time of signing the Informed Consent Form (ICF)

Exclusion Criteria:

* Not eligible for cardiac rehabilitation according to current guidelines
* Unable to perform the physical performance test due to physical or mental issues as up to decision by supervising cardiologist

Where it's running

  • UZ Leuven
    Leuven, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.