Sarcopenia in Patients After Cardiac Surgery
Official title: Sarcopenia After Cardiac Surgery: An Overlooked Target for Therapeutic Optimization?
Run by Universitaire Ziekenhuizen KU Leuven · NCT07908472 · Data updated 2026-11-12
This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven) |
| Status | Recruiting |
| Started | February 5, 2026 |
| Main results expected | June 2028 |
| Study ends | June 2028 |
| Registry record updated | November 2, 2026 |
| Trial ID | NCT07908472 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who have been hospitalized after cardiac surgery, are stable, and are eligible for cardiac rehabilitation after discharge.
✕Probably not a fit
Patients who do not undergo or complete cardiac rehabilitation or who have conditions making functional testing inappropriate may derive little benefit from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to measure the prevalence of sarcopenia in patients who have recently undergone cardiac surgery and to see if standard post-discharge care is sufficient to improve sarcopenia outcomes. Participants will be assessed for sarcopenia one day before hospital discharge and then again at 4 weeks, 16 weeks, and/or 1 year, depending on baseline status and participation in a cardiac rehabilitation program. The study follows existing guidelines on sarcopenia management and does not involve any experimental intervention. It describes real-world practice and associations between rehabilitation participation and sarcopenia trajectories in this population.
Why it matters
Potential benefit: If successful, the study could clarify whether current post-surgical care supports muscle health and guide improvements in rehabilitation strategies.
How similar studies have gone: There is prior evidence that sarcopenia is common in cardiovascular patients, but this study adds real-world post-surgical data and may be among the first to track longitudinal outcomes without an intervention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Hospitalized following cardiac surgery (i.e. hospitalization unit 18 and 22) * Stable with regard to symptoms * Eligible for cardiac rehabilitation according to current guidelines following hospital discharge * Voluntary written informed consent of the participant has been obtained * At least 18 years of age at the time of signing the Informed Consent Form (ICF) Exclusion Criteria: * Not eligible for cardiac rehabilitation according to current guidelines * Unable to perform the physical performance test due to physical or mental issues as up to decision by supervising cardiologist
Where it's running
-
UZ Leuven
Leuven, Belgium Recruiting
Study contacts
- Study coordinator: Véronique Cornelissen
- Email: veronique.cornelissen@kuleuven.be
- Phone: +3216329152
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.