Effects of nitrogen pollution on pollen allergies in Belgium
Official title: Impacts of Nitrogen Deposition in the Natural Environment on Pollen Allergy in Belgium
Run by Universitaire Ziekenhuizen KU Leuven · NCT06714149 · Data updated 2026-11-12
This study is testing how nitrogen pollution affects allergy symptoms in people who are sensitive to pollen in Belgium.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven, Vlaams-Brabant) |
| Status | Recruiting |
| Started | June 29, 2022 |
| Main results expected | February 2025 |
| Study ends | April 2025 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT06714149 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with a positive skin prick test for grass and/or birch pollen.
✕Probably not a fit
Patients who have undergone desensitization therapy in the last two years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how nitrogen enrichment in the environment affects allergy symptoms in individuals sensitized to pollen. It involves analyzing allergen-specific IgE reactivity in pollen-allergic patients and comparing their responses to various pollen samples. The study will assess basophil degranulation thresholds and the qualitative and quantitative reactivity to different pollen fragments. Additionally, it aims to correlate allergy symptoms with the reactivity to these pollen samples.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of pollen allergies in relation to environmental factors.
How similar studies have gone: While studies on environmental impacts on allergies exist, this specific focus on nitrogen deposition and its direct effects on pollen allergy is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Positive skin prick test for grass and/or birch pollen Exclusion Criteria: * Desensitization therapy during the last two years
Where it's running
-
University Hospitals Leuven
Leuven, Vlaams-Brabant, Belgium Recruiting
Study contacts
- Study coordinator: Rik Schrijvers, MD, PhD
- Email: rik.schrijvers@uzleuven.be
- Phone: +3216342985
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.