Investigating imaging techniques for diagnosing non-convulsive status epilepticus

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of three imaging techniques—FDG-PET, perfusion MRI, and CT perfusion—in diagnosing possible non-convulsive status epilepticus (NCSE). It will involve 180 patients with NCSE and 20 control subjects, focusing on identifying brain hypermetabolism and hyperperfusion as indicators of the condition. The study will also analyze EEG patterns associated with these imaging findings and assess the management and outcomes of patients based on their imaging results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- The patient has possible non-convulsive status epilepticus with scalp or invasive EEG with ictal-interictal continuum patterns on EEG

Exclusion Criteria:

* The patient has a contra-indication for MRI such as metal implants
* The patient has contrast sensitivity
* The patiensuffers from claustrophobia or cannot tolerate confinement during PET-MRI scanning procedures

Where it's running

• University Hospitals Leuven, department of Neurology
  Leuven, Belgium Recruiting

Study contacts

• Principal investigator: Wim Van Paesschen, MD PhD — UZ Leuven
• Study coordinator: Wim Van Paesschen, MD PhD
• Email: Wim.vanpaesschen@kuleuven.be
• Phone: +3216344332

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.